The results are sorted from lowest E-value to highest E-value. Strong classifications have a low E-value. Weak classifications have an E-value greater than 0.0001. Weak hits are shown in gray. Weak hits are not shown on the domain architecture.
The family level classification is conditional on the domain being a member of the specified superfamily. There is a possibility that the selected domain is a member of a sub-family for which no structure has yet been solved.
| Sequence: |
ENSCAFP00000018218 |
| Domain Number 1 |
Region: 1377-1428,1474-1654 |
| Classification Level |
Classification |
E-value |
| Superfamily |
VPS9 domain |
1.2e-41 |
| Family |
VPS9 domain |
0.0021 |
| Further Details: |
|
| |
| Domain Number 2 |
Region: 12-218 |
| Classification Level |
Classification |
E-value |
| Superfamily |
RCC1/BLIP-II |
1.15e-36 |
| Family |
Regulator of chromosome condensation RCC1 |
0.0047 |
| Further Details: |
|
| |
| Domain Number 3 |
Region: 519-686 |
| Classification Level |
Classification |
E-value |
| Superfamily |
RCC1/BLIP-II |
6.54e-27 |
| Family |
beta-lactamase inhibitor protein-II, BLIP-II |
0.066 |
| Further Details: |
|
| |
| Domain Number 4 |
Region: 1046-1135 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain |
1.29e-23 |
| Family |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain |
0.0099 |
| Further Details: |
|
| |
| Domain Number 5 |
Region: 1140-1248 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain |
2.35e-18 |
| Family |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain |
0.024 |
| Further Details: |
|
| |
| Domain Number 6 |
Region: 926-1012 |
| Classification Level |
Classification |
E-value |
| Superfamily |
PH domain-like |
0.0000000000137 |
| Family |
Pleckstrin-homology domain (PH domain) |
0.024 |
| Further Details: |
|
| |
| Domain Number 7 |
Region: 691-890 |
| Classification Level |
Classification |
E-value |
| Superfamily |
DBL homology domain (DH-domain) |
0.0000000000563 |
| Family |
DBL homology domain (DH-domain) |
0.0064 |
| Further Details: |
|
| |
The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by 
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Information Content (IC) is an information theoretic score measured in bits of how informative it is to assign a given ontological term to a domain archtecture. The higher the score the more informative it is to talk about the term given the domain architecture.
H-score (hypergeometric score) indicates the strength of assigning an ontological term to this domain architecture. Assignments with higher scores are of a better quality. Details for the methodology be found on the dcGO website.
| Biological Process |
IC (bits) |
H-Score |
| Cellular Component |
IC (bits) |
H-Score |
| Molecular Function |
IC (bits) |
H-Score |
