The results are sorted from lowest E-value to highest E-value. Strong classifications have a low E-value. Weak classifications have an E-value greater than 0.0001. Weak hits are shown in gray. Weak hits are not shown on the domain architecture.
The family level classification is conditional on the domain being a member of the specified superfamily. There is a possibility that the selected domain is a member of a sub-family for which no structure has yet been solved.
| Sequence: |
FBpp0083348 |
| Domain Number 1 |
Region: 752-1078 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Protein kinase-like (PK-like) |
1.53e-88 |
| Family |
Phoshoinositide 3-kinase (PI3K), catalytic domain |
0.000000124 |
| Further Details: |
|
| |
| Domain Number 2 |
Region: 532-722 |
| Classification Level |
Classification |
E-value |
| Superfamily |
ARM repeat |
6.24e-53 |
| Family |
Phoshoinositide 3-kinase (PI3K) helical domain |
0.000046 |
| Further Details: |
|
| |
| Domain Number 3 |
Region: 345-511 |
| Classification Level |
Classification |
E-value |
| Superfamily |
C2 domain (Calcium/lipid-binding domain, CaLB) |
1.08e-44 |
| Family |
PLC-like (P variant) |
0.0057 |
| Further Details: |
|
| |
| Domain Number 4 |
Region: 136-305 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Ubiquitin-like |
2.7e-35 |
| Family |
Ras-binding domain, RBD |
0.0026 |
| Further Details: |
|
| |
The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by 
(show help)
Information Content (IC) is an information theoretic score measured in bits of how informative it is to assign a given ontological term to a domain archtecture. The higher the score the more informative it is to talk about the term given the domain architecture.
H-score (hypergeometric score) indicates the strength of assigning an ontological term to this domain architecture. Assignments with higher scores are of a better quality. Details for the methodology be found on the dcGO website.
| Cellular Component |
IC (bits) |
H-Score |
| Biological Process |
IC (bits) |
H-Score |
| Molecular Function |
IC (bits) |
H-Score |
| External link(s) |
Protein: FBpp0083348 Gene: FBgn0015279 Transcript: FBtr0083940 |
| Sequence length |
1088 |
| Comment |
type=protein; loc=3R:complement(16455469..16455597,16455661..16455780,16455849..16456019,16456079..16456385,16456442..16457029,16457231..16457437,16457500..16459244); ID=FBpp0083348; name=Pi3K92E-PA; parent=FBgn0015279,FBtr0083940; dbxref=FlyBase:FBpp0083348,FlyBase_Annotation_IDs:CG4141-PA,GB_protein:AAF55792.1,REFSEQ:NP_650902,GB_protein:AAF55792,FlyMine:FBpp0083348,modMine:FBpp0083348; MD5=3af9bc06a7c1bc81aaa07d01cd7141db; length=1088; release=r5.30; species=Dmel; |
| Sequence |
MNMMDNRALAYVAHQPKYETPPEEAEPPCMRFSVNLWKNEMLNWVDLICLLPNGFLLELR
VNPANTIQVIKVEMVNQAKQMPLGYVIKEACEYQVYGISTFNIEPYTDETKRLSEVQPYF
GILSLGERTDTTSFSSDYELTKMVNGMIGTTFDHNRTHGSPEIDDFRLYMTQTCDNIELE
RSAYTWQQRLLYEHPLRLANSTKMPELIRERHPTRTFLIVVKNENDQSTFTLSVNEQDTP
FSLTESTLQKMNRSQMKMNDRTSDYILKVSGRDEYLLGDYPLIQFLYIQEMLSDSAVPNV
VLQSVYRLESYINHHNEQAMVTKRPLPKKRTVHLHKSISSLWDMGNYFQLTLHSISNVNF
DKTRALKVGVHVCLYHGDKKLCAQRSTDSPNGNFDTFLFNDLVMDFDIQMRNLPRMTRLC
IVIFEVTKMSRSKKSSNNKDIALKDVPYNKNPLAWVNTTIFDHKDILRTGRHTLYTWTYA
DDIQSVEVFHPLGTIEPNPRKEECALVDLTFLSSGTGTVRYPSEEVVLQYAADREQVNRL
QRQLAGPEKPIKELKELMANYTGLDKIYEMVDQDRNAIWERRNDILRELPEELSILLHCV
YWKERDDVADMWYLLKQWPLISIERSLELLDYAYPDPAVRRFAIRCLHFLKDEDLLLYLL
QLVQAIKHESYLESDLVVFLLERALRNQRIGHYFFWHLRSEMQTPSMQTRFGLLLEVYLK
GCKHHVAPLRKQLHVLEKLKQGSLIAKKGSKEKVKTMLQDFLRDQRNSAVFQNIQNPLNP
SFRCSGVTPDRCKVMDSKMRPLWVVFENADVNASDVHIIFKNGDDLRQDMLTLQMLRVMD
QLWKRDGMDFRMNIYNCISMEKSLGMIEVVRHAETIANIQKEKGMFSATSPFKKGSLLSW
LKEHNKPADKLNKAINEFTLSCAGYCVATYVLGVADRHSDNIMVKRNGQLFHIDFGHILG
HFKEKLGVRRERVPFVLTHDFVYVINKGFNDRESKEFCHFQELCERAFLVLRKHGCLILS
LFSMMISTGLPELSSEKDLDYLRETLVLDYTEEKAREHFRAKFSEALANSWKTSLNWASH
NFSKNNKQ
|
| Download sequence |
 |
| Identical sequences |
P91634
FBpp0083348 FBpp0083349 FBpp0083348 FBpp0083349 NP_001262770.1.81976 NP_650902.1.81976 NP_732536.1.81976 7227.FBpp0083348 FBpp0083348 |
