The results are sorted from lowest E-value to highest E-value. Strong classifications have a low E-value. Weak classifications have an E-value greater than 0.0001. Weak hits are shown in gray. Weak hits are not shown on the domain architecture.
The family level classification is conditional on the domain being a member of the specified superfamily. There is a possibility that the selected domain is a member of a sub-family for which no structure has yet been solved.
Sequence: |
FBpp0088356 |
Domain Number 1 |
Region: 213-458 |
Classification Level |
Classification |
E-value |
Superfamily |
Metalloproteases ("zincins"), catalytic domain |
4.64e-67 |
Family |
Leukotriene A4 hydrolase catalytic domain |
0.000000157 |
Further Details: |
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Domain Number 2 |
Region: 8-205 |
Classification Level |
Classification |
E-value |
Superfamily |
Leukotriene A4 hydrolase N-terminal domain |
7.06e-47 |
Family |
Leukotriene A4 hydrolase N-terminal domain |
0.0000101 |
Further Details: |
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Domain Number 3 |
Region: 466-612 |
Classification Level |
Classification |
E-value |
Superfamily |
ARM repeat |
2.01e-32 |
Family |
Leukotriene A4 hydrolase C-terminal domain |
0.00051 |
Further Details: |
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The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by 
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Information Content (IC) is an information theoretic score measured in bits of how informative it is to assign a given ontological term to a domain archtecture. The higher the score the more informative it is to talk about the term given the domain architecture.
H-score (hypergeometric score) indicates the strength of assigning an ontological term to this domain architecture. Assignments with higher scores are of a better quality. Details for the methodology be found on the dcGO website.
Molecular Function |
IC (bits) |
H-Score |
Biological Process |
IC (bits) |
H-Score |
Cellular Component |
IC (bits) |
H-Score |
External link(s) |
Protein: FBpp0088356 Gene: FBgn0032721 Transcript: FBtr0089314 |
Sequence length |
613 |
Comment |
type=protein; loc=2L:complement(18855253..18856077,18856143..18856848,18856916..18857064,18857177..18857338); ID=FBpp0088356; name=CG10602-PD; parent=FBgn0032721,FBtr0089314; dbxref=FlyBase:FBpp0088356,FlyBase_Annotation_IDs:CG10602-PD,GB_protein:AAN11017.1,REFSEQ:NP_724140,GB_protein:AAN11017; MD5=87c31d98fb379418d3651328c01d2160; length=613; release=r5.30; species=Dmel; |
Sequence |
MGRLGVVDPSSYSQPDLITTEHSALNWKIDFAATKIQGSVLHRFKVLTANLDKILLDVRD
INVTNATLLAGGSELPINFFISDAVDDIGQKLTLELPSGTAKGSLNVRIDYETSSSASGL
QWLNPTQTLGKEHPYMFSQCQAIHARSVIPCQDTPAVKFTYDATVEHPSELTALMSALID
KKEPGKTLFKQEVPIPAYLVAIAIGKLVSRPLGENSSVWAEEAIVDACAEEFSETATMLK
TATELCGPYVWKQYDLLVMPPSFPFGGMENPCLTFVTPTLLAGDKSLADVVAHEIAHSWT
GNLVTNKNFEHFWLNEGFTVFVESKIVGRMQGAKELDFKMLSNLTDLQECIRTQLNKTPE
LTKLVVDLSNCGPDDAFSSVPYIKGSTFLRYLEDLFGGPTVFEPFLRDYLKKYAYKSIET
KDFQSALYDYFIDTDKKDKLSAVDWDLWLKSEGMPPVIPNFDESLANVTKELASLWSSKS
VAELADSAEIKTTISIHQLIDFLGKLIESKDIVDLNEGKINLLESTYNLKSSKNAEVRFR
LNRLIIRARLIKRLDEILEFANSNFRMKFCRPIYRDLAGWPEAKPAAIRNFVNVKDQMMA
VCSHTIEKDLGLK
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Download sequence |
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Identical sequences |
A4V0U4
FBpp0088356 FBpp0088356 FBpp0088357 FBpp0088358 7298498___KOG1047 NP_724139.1.81976 NP_724140.1.81976 FBpp0088356 FBpp0088357 FBpp0088358 FBpp0300412 |