The results are sorted from lowest E-value to highest E-value. Strong classifications have a low E-value. Weak classifications have an E-value greater than 0.0001. Weak hits are shown in gray. Weak hits are not shown on the domain architecture.
The family level classification is conditional on the domain being a member of the specified superfamily. There is a possibility that the selected domain is a member of a sub-family for which no structure has yet been solved.
Sequence: |
FBpp0074075 |
Domain Number 1 |
Region: 186-301 |
Classification Level |
Classification |
E-value |
Superfamily |
eIF-2-alpha, C-terminal domain |
1.57e-36 |
Family |
eIF-2-alpha, C-terminal domain |
0.0000166 |
Further Details: |
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Domain Number 2 |
Region: 89-181 |
Classification Level |
Classification |
E-value |
Superfamily |
eIF2alpha middle domain-like |
2.09e-32 |
Family |
eIF2alpha middle domain-like |
0.0000885 |
Further Details: |
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Domain Number 3 |
Region: 11-91 |
Classification Level |
Classification |
E-value |
Superfamily |
Nucleic acid-binding proteins |
4.86e-18 |
Family |
Cold shock DNA-binding domain-like |
0.0000399 |
Further Details: |
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The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by 
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Information Content (IC) is an information theoretic score measured in bits of how informative it is to assign a given ontological term to a domain archtecture. The higher the score the more informative it is to talk about the term given the domain architecture.
H-score (hypergeometric score) indicates the strength of assigning an ontological term to this domain architecture. Assignments with higher scores are of a better quality. Details for the methodology be found on the dcGO website.
Cellular Component |
IC (bits) |
H-Score |
Molecular Function |
IC (bits) |
H-Score |
Biological Process |
IC (bits) |
H-Score |
External link(s) |
Protein: FBpp0074075 Gene: FBgn0261609 Transcript: FBtr0074300 |
Sequence length |
341 |
Comment |
type=protein; loc=X:complement(16339588..16339918,16340218..16340912); ID=FBpp0074075; name=eIF-2alpha-PA; parent=FBgn0261609,FBtr0074300; dbxref=FlyBase:FBpp0074075,FlyBase_Annotation_IDs:CG9946-PA,GB_protein:AAF48615.1,REFSEQ:NP_573130,GB_protein:AAF48615,FlyMine:FBpp0074075,modMine:FBpp0074075; MD5=e3f0b632583d5204c5d718cb0d2136ca; length=341; release=r5.30; species=Dmel; |
Sequence |
MALTSRFYNERYPEIEDVVMVNVLSIAEMGAYVHLLEYNNIEGMILLSELSRRRIRSINK
LIRVGKTEPVVVIRVDKEKGYIDLSKRRVSPEDVEKCTERFAKAKAINSLLRHVADILGF
EGNEKLEDLYQKTAWHFEKKYNNKTVAYDIFKQSVTDPTVFDECNLEPETKEVLLSNIKR
KLVSPTVKIRADIECSCYGYEGIDAVKASLTKGLELSTEELPIRINLIAPPLYVMTTSTT
KKTDGLKALEVAIEHIRAKTSEYDGEFKVIMAPKLVTAIDEADLARRLERAEAENAQVAG
DDDEEDGADQEGMQFDPEKEFNHKGSGAGRANEEDEEEEED
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Download sequence |
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Identical sequences |
P41374 X2JFR6
FBpp0074075 NP_001285329.1.81976 NP_573130.1.81976 7293233___KOG2916 7227.FBpp0074075 FBpp0074075 FBpp0074075 |