The results are sorted from lowest E-value to highest E-value. Strong classifications have a low E-value. Weak classifications have an E-value greater than 0.0001. Weak hits are shown in gray. Weak hits are not shown on the domain architecture.
The family level classification is conditional on the domain being a member of the specified superfamily. There is a possibility that the selected domain is a member of a sub-family for which no structure has yet been solved.
Sequence: |
FBpp0085148 |
Domain Number 1 |
Region: 518-597,691-896 |
Classification Level |
Classification |
E-value |
Superfamily |
Protein kinase-like (PK-like) |
3.34e-61 |
Family |
Protein kinases, catalytic subunit |
0.00027 |
Further Details: |
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Domain Number 2 |
Region: 7-136 |
Classification Level |
Classification |
E-value |
Superfamily |
UBC-like |
6.87e-30 |
Family |
RWD domain |
0.00021 |
Further Details: |
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Domain Number 3 |
Region: 972-1151,1178-1295 |
Classification Level |
Classification |
E-value |
Superfamily |
Class II aaRS and biotin synthetases |
3.87e-21 |
Family |
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain |
0.0049 |
Further Details: |
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Domain Number 4 |
Region: 305-480 |
Classification Level |
Classification |
E-value |
Superfamily |
Protein kinase-like (PK-like) |
2.74e-16 |
Family |
Protein kinases, catalytic subunit |
0.0059 |
Further Details: |
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The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by 
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Information Content (IC) is an information theoretic score measured in bits of how informative it is to assign a given ontological term to a domain archtecture. The higher the score the more informative it is to talk about the term given the domain architecture.
H-score (hypergeometric score) indicates the strength of assigning an ontological term to this domain architecture. Assignments with higher scores are of a better quality. Details for the methodology be found on the dcGO website.
Biological Process |
IC (bits) |
H-Score |
Cellular Component |
IC (bits) |
H-Score |
Molecular Function |
IC (bits) |
H-Score |
External link(s) |
Protein: FBpp0085148 Gene: FBgn0019990 Transcript: FBtr0085787 |
Sequence length |
1589 |
Comment |
type=protein; loc=3R:join(27221713..27221778,27221845..27222014,27222124..27222629,27222708..27223335,27223389..27223961,27224027..27224203,27224268..27224766,27224825..27225877,27225940..27226910,27226973..27227099); ID=FBpp0085148; name=Gcn2-PA; parent=FBgn0019990,FBtr0085787; dbxref=FlyBase:FBpp0085148,FlyBase_Annotation_IDs:CG1609-PA,GB_protein:AAF57150.1,REFSEQ:NP_477230,GB_protein:AAF57150,FlyMine:FBpp0085148,modMine:FBpp0085148; MD5=83300fb3c7aa4d951a0d50fb10ecadc8; length=1589; release=r5.30; species=Dmel; |
Sequence |
MADEKAKESFRERQAQELEVIKSIFGCDVEDLRPQANPSLWKPTDIRIQLTPLRDSSNGL
ETYVCTKLHVTCPSKYPKLPPKISLEESKGMSDQLLEALRNQLQAQSQELRGEVMIYELA
QTVQAFLLEHNKPPKGSFYDQMLQDKQKRDQELQDIQRQRESLQRQTLIDEVERRKEMFK
TEAKRRGEPRRSMSESNPRHPSSSESSENSSPYYRGHIYPSKCLDHRNTETLYFHKMGRQ
IQRGCCVGHSQRGCIAYTGIDMHCGQLLYITEWNIKYSQLEQPCIGGGKCHWSSESKCMG
SHRVDEVMASIEKQVSSLSQLQHKNLVSYECVLCIKRKEGLLVYLVQDFLLGTSVFSISS
SLGWCMDGARMVARGVLDALVFLHNKGVSHSHLLDTTVFMDNTGNVRVSDFSLVPNLLEL
LSGAGQSSSCGDLPALGALVESLMPTNSYEMRDFVDKCNSDRTLSASELLEHPFLRFYVD
NGQQQVMPLPQQQHPNTVQRTGSAMPYQIPTLALSQSRLRTEFEVLMYLGKGAFGDVLKV
RNILDNREYAIKRIPLPARSRQLYKKMTREVELLSRLNHENVVRYFNSWIESVDDADAAE
MDKLLGGEWSQSQQDLSVKPAKSPQLGPTLEEDEDEEDSSSSMWNGYIPNMEDSDSDGIE
FVDSNGKVAVYDDEEQEDSTRGKTNSPKPLMQVMYIQMEFCEKCTLRTAIDDNLFNDTDR
LWRLFREIAEGLAHIHQQGIIHRDLKPVNIFLDSHDQIKIGDFGLATTSFLALQAHDAAP
APVNQITSAEDGTGTGKVGTTLYVAPELTGNASKSVYNQKVDMYTLGIILFEMCQPPFDT
SMERAQTIMALRNVSINIPDAMLKDPKYEKTVKMLQWLLNHDPAQRPTAEELLISDLVPP
AQLEANELQEMLRHALANPQSKAYKNLVARCLQQESDEVLEHTYHLGSSRAMKSWNSAII
IDDIVSLNPVIEFVKAKVVNLFRKHGAIEVDSPLLSPLSARNSTANANANAVHLMTHSGC
VVVLPCDLRTQFARHVTMNSVNLIRRYCVDRVYREERVFNFHPKQSYDCSFDIIAPTTGS
HLVDAELLSLAFEITSELPRLREKNLAIRMNHTNLLRAILIFCNVPKAQYGALFEGTMDF
IESRISRFQFHSSITGIMEKSRTSAQTLMDMLLANFLLTGSRSTVDDSALKSLMRGKGEA
ASLARGALRELETVVGLAYSLGVKCPIHIWAGLPISFDRASNGGIVWQMTADLKPNRSGH
PSVLAIGERYDSMLHEFQKQAQKFNPAMPARGVLSGAGLTFSLDKLVAAVGVEYAKDCRA
IDVGICVCGTRPPLKDVTYIMRLLWSVGIRCGIVEAASELGDEAQDLARLGALHVILVAE
NGSLRVRSFERERFQERHLTRTELVEFIQKMLRSDGLNGTTVDNFSQLSALGSGDNRSSG
GKERERGENGLSTSASNATIKNNYSQLPNLQVTFLTHDKPTANYKRRLENQVAQQMSSTL
SQFLKKETFVVLVVELPPAVVNAIVGAINPREIRKRETEPEINYVIERFSKYKRYISEIN
EEVVDYLSDAKTPIVALYSISDSYYRVII
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Download sequence |
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Identical sequences |
Q9V9X8
7227.FBpp0085148 FBpp0085148 FBpp0085148 NP_001263141.1.81976 NP_477230.1.81976 FBpp0085148 |