The results are sorted from lowest E-value to highest E-value. Strong classifications have a low E-value. Weak classifications have an E-value greater than 0.0001. Weak hits are shown in gray. Weak hits are not shown on the domain architecture.
The family level classification is conditional on the domain being a member of the specified superfamily. There is a possibility that the selected domain is a member of a sub-family for which no structure has yet been solved.
Sequence: |
FBpp0111729 |
Domain Number 1 |
Region: 419-640 |
Classification Level |
Classification |
E-value |
Superfamily |
DBL homology domain (DH-domain) |
6.41e-54 |
Family |
DBL homology domain (DH-domain) |
0.00017 |
Further Details: |
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Domain Number 2 |
Region: 116-234 |
Classification Level |
Classification |
E-value |
Superfamily |
BRCT domain |
1.4e-20 |
Family |
DNA topoisomerase II binding protein 1, TopBP1 |
0.054 |
Further Details: |
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Domain Number 3 |
Region: 253-337 |
Classification Level |
Classification |
E-value |
Superfamily |
BRCT domain |
0.000000000000119 |
Family |
DNA topoisomerase II binding protein 1, TopBP1 |
0.032 |
Further Details: |
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Domain Number 4 |
Region: 632-749 |
Classification Level |
Classification |
E-value |
Superfamily |
PH domain-like |
0.00000516 |
Family |
Pleckstrin-homology domain (PH domain) |
0.03 |
Further Details: |
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The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by 
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Information Content (IC) is an information theoretic score measured in bits of how informative it is to assign a given ontological term to a domain archtecture. The higher the score the more informative it is to talk about the term given the domain architecture.
H-score (hypergeometric score) indicates the strength of assigning an ontological term to this domain architecture. Assignments with higher scores are of a better quality. Details for the methodology be found on the dcGO website.
Biological Process |
IC (bits) |
H-Score |
Molecular Function |
IC (bits) |
H-Score |
Cellular Component |
IC (bits) |
H-Score |
External link(s) |
Protein: FBpp0111729 Gene: FBgn0003041 Transcript: FBtr0112817 |
Sequence length |
900 |
Comment |
type=protein; loc=3L:complement(7889824..7889952,7890012..7890161,7890222..7890332,7890398..7891339,7891403..7891753,7891823..7891954,7894715..7894964,7895059..7895165,7895240..7895375,7900222..7900438,7902261..7902438); ID=FBpp0111729; name=pbl-PE; parent=FBgn0003041,FBtr0112817; dbxref=FlyBase:FBpp0111729,FlyBase_Annotation_IDs:CG8114-PE,REFSEQ:NP_001097540,GB_protein:ABW08489,FlyMine:FBpp0111729,modMine:FBpp0111729; MD5=13d7b8c17e15c78b2846d83b4c266e09; length=900; release=r5.30; species=Dmel; |
Sequence |
MLHLPLVQFNFGNHLGKKSNKVVTVQRQSASYFTYAADEEVKQAKLRQAALCQVYEDFTE
MSITTLPTRICLVGGVGQDADTLQAAESFGLPIVTSDTGLDILGESSDWRTFYVLDDFEG
ASFEAIHKQKECILGPPALKYAAEMKQTLGQNSRPIYNYAMRGVVTCFTGIRKKDELTKL
VNLIHSMGGCIKKDLNTKTTHLICNHSGGEKYQYAKTFRLTVVRPAWVFAAWADRNSLEF
DATQENFTKTHRLKAFEGQKICFFGFPVEEHQHMVDVLLENGGVCAELDDPECSHVVVDE
HTTLTKPEPKNNHTHILKSDWFWYTIQNGYANEMDYLFGDYLDSITNTPNTDRRDSLPIS
FNKRKRKRFSQRIQLEGTPLGSGKRRSSVSDAGLLSVSNSLFDCTTSPDKLESDKLLHAE
PEASDATPAKKSMRFNHFMDFYTTESNYVGILDTILNLFKNKLEELAETNDPLLNKSEIK
TIFGNFLPIHEVHQSMLEHLRKLHANWREDCLIGDIIIQHRDELIKAYPPYVNFFEQMKE
QLQYCDREYPRFHAFLKINQTKPECGRQGLQDLMIRPVQRLPSISLLLNDILKHTTSGNA
DHGRLEEALKAIKQVTLHINEDKRRTESRMAIFDIFNDIEGCPAHLVSSNRSFILKCEVN
ELSDSLSGRGDSLVLYLFSDSIELCKRRSKGFNTAKSPSTAKTHKHLKLISLNTIRLVID
ISDSPRAFGLLLRGDKEKLYTFTISDEETDKSVYVKKLCNQIAAHTCRTDADKLLICRTS
QELEVDISDVNVSTLSKAFKLAAKTRLKVGRAFSFNKTPNKLKRAVSTMMTSPFGSTNSL
TPASQLAQMRLASCTNINEVDDEDCASMRSSSPSTQSEMLVVPPLSVQPTRKNKAVVGRI
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Download sequence |
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Identical sequences |
A8JNN0
FBpp0111729 NP_001097540.1.81976 FBpp0111729 |