The results are sorted from lowest E-value to highest E-value. Strong classifications have a low E-value. Weak classifications have an E-value greater than 0.0001. Weak hits are shown in gray. Weak hits are not shown on the domain architecture.
The family level classification is conditional on the domain being a member of the specified superfamily. There is a possibility that the selected domain is a member of a sub-family for which no structure has yet been solved.
| Sequence: |
FBpp0290558 |
| Domain Number 1 |
Region: 2986-3354 |
| Classification Level |
Classification |
E-value |
| Superfamily |
RCC1/BLIP-II |
1.83e-98 |
| Family |
Regulator of chromosome condensation RCC1 |
0.0051 |
| Further Details: |
|
| |
| Domain Number 2 |
Region: 4048-4417 |
| Classification Level |
Classification |
E-value |
| Superfamily |
RCC1/BLIP-II |
6.8e-98 |
| Family |
Regulator of chromosome condensation RCC1 |
0.0039 |
| Further Details: |
|
| |
| Domain Number 3 |
Region: 4549-4876 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Hect, E3 ligase catalytic domain |
2.22e-83 |
| Family |
Hect, E3 ligase catalytic domain |
0.0001 |
| Further Details: |
|
| |
| Domain Number 4 |
Region: 533-899 |
| Classification Level |
Classification |
E-value |
| Superfamily |
RCC1/BLIP-II |
1.13e-66 |
| Family |
Regulator of chromosome condensation RCC1 |
0.011 |
| Further Details: |
|
| |
| Domain Number 5 |
Region: 2624-2700 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Tudor/PWWP/MBT |
1.5e-25 |
| Family |
CPH domain |
0.00079 |
| Further Details: |
|
| |
| Domain Number 6 |
Region: 1922-1989 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Mib/herc2 domain-like |
1.7e-19 |
| Family |
Mib/herc2 domain |
0.00018 |
| Further Details: |
|
| |
| Domain Number 7 |
Region: 2804-2933 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Galactose-binding domain-like |
1.28e-18 |
| Family |
APC10-like |
0.0094 |
| Further Details: |
|
| |
| Domain Number 8 |
Region: 2483-2559 |
| Classification Level |
Classification |
E-value |
| Superfamily |
UBA-like |
0.00000133 |
| Family |
UBA domain |
0.013 |
| Further Details: |
|
| |
| Sequence: |
FBpp0290558 |
| Domain Number - |
Region: 3664-3751 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Spermadhesin, CUB domain |
0.000118 |
| Family |
Spermadhesin, CUB domain |
0.007 |
| Further Details: |
|
| |
| Domain Number - |
Region: 1288-1364 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Cytochrome b5-like heme/steroid binding domain |
0.0336 |
| Family |
Cytochrome b5 |
0.018 |
| Further Details: |
|
| |
The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by 
(show help)
Information Content (IC) is an information theoretic score measured in bits of how informative it is to assign a given ontological term to a domain archtecture. The higher the score the more informative it is to talk about the term given the domain architecture.
H-score (hypergeometric score) indicates the strength of assigning an ontological term to this domain architecture. Assignments with higher scores are of a better quality. Details for the methodology be found on the dcGO website.
| Molecular Function |
IC (bits) |
H-Score |
| Cellular Component |
IC (bits) |
H-Score |
| Biological Process |
IC (bits) |
H-Score |
| External link(s) |
Protein: FBpp0290558 Gene: FBgn0031107 Transcript: FBtr0301344 |
| Sequence length |
4912 |
| Comment |
type=protein; loc=X:join(20265907..20267809,20269150..20269718,20269783..20270331,20270400..20271337,20271408..20271564,20271625..20273387,20273447..20273820,20273891..20281562,20281632..20282115,20282185..20282361,20282429..20282581); ID=FBpp0290558; name=HERC2-PC; parent=FBgn0031107,FBtr0301344; dbxref=REFSEQ:NP_608388,GB_protein:AAF50913,FlyBase:FBpp0290558,FlyBase_Annotation_IDs:CG11734-PC,FlyMine:FBpp0290558,modMine:FBpp0290558; MD5=aeb7dcb8257acff11282c408887e1f9e; length=4912; release=r5.30; species=Dmel; |
| Sequence |
MFNRQASGGAGSSGQGAGSSQTASAAPVSAGVGVGGGGGASGAAAGAGSAAGSGSGSGSG
SAAPPSHSPDLYLRPLPFLDAKWLRADLIASLRNAADGAVLWNHLIQDCELVSSPTAPLL
NARGQLSYLGDDGKHYCGAQQLKCSCCQPEYCGPLSACNCDGCRPLDSDTAIKKLTTQAA
AQQAAHLSQATDMVLSGWLWSQPPSQQARLDCQRSMISELQELALRAAGNCLSAQHLRQQ
LFIYERYFVALKRERERERKSTTSAQAVASVTTANTTIAATTANAAVESQPAEQQAEHGA
LGLARVATHAALNFSFAFLRRAWRSGEDTEMCSELLSEALASLQELPEATLFEAAVVSSL
WLEVMERSIKFLRLVALGDPMGNRCTAPLNDRHTALCLLLELGVQKGTLAATLECVVLLL
LLWEKDRAGNDNRDMPRKTGAPLQRILLRYQKIGATAKGGGIAGGEPAPVASATETFLRF
LSLPKSSAAIVDLRRAAVVIISHLDRMVQPLMPRCLLRGGQATAASSSSAPQQRIYALGW
PSLSKDQQGFSAEPTLSWSGESAGVPTLSCRFQIKQVACCETQMLILSQEGKLYTWRLAK
PEAEPLPMEEVAHDVFISIAGHCEGRHFLAIDSNHNAYSWGTGEDHRLGHGDTHARAVPT
KIAALEQHCVQSVYCGCSYSAAITCGGNLLTWGRGTYARLGHGNSDDRSLPTLVVALSDH
MVVDVALGSGDAHSLALTSEGLVFAWGDGDYGKLGNGNCNGSLQPILVESLPRVQRVFAG
SQFSVALSSEGQLYTWGKATCLGHQLVERSVQGCSVPRLVSSLQHKRIVDVAVSVAHCLA
LSSSGEVFGWGRNDSQQICPASVSSEPLLRTPILVSLPTFPASGIACTSAQSLVWTQSSH
QGVPRRAPFVVDLGEPTFRLLDQLLGMCSSQDNRQTPNQESECIAVACLNLFRLQLLALI
ANGVEPRQVGLASGSRLLCSLKTRILGLAGGSQVLRTIQVAAQQALQDGWSVLLPTAAER
AQTLTSLLPSEPGQASSAGHRFMTDLLVSSLMAEGGLESALQHAIRLESSSCSADCGDGV
HLPLLQLITRLLSNNAALSQTRLSPTLGKQQEKEEEEREQQHQEPSTSPSLSLLHRFQRL
LLSHIHQAQPEEETTGAEALLLQYMHALIPACVATLQKAHELALQCREPGENSFGQMVGH
LGRVLQADISDALLNELLVGLLLLKRDRPQCLGGLRWARLFLPLLRVLDRLNRALGEGEL
RDGDDMGWPGIICRGGPKGGPPPADPETHYVRRADMENLLLDGSRCIILAGYVCDLSGYN
CESETLRSVLDSGLGKDLTAEMSSQVHRTAMEHILEHHKLGKYMVQASTEEKSSAPGPSR
LTHFSSECALAQLLGLVANLMCSGPALQPAELQCRQLDKSSLLSGGLQLLQPSNPFDEEK
GEARSSHSCHSTAGNTPTELPPPLPMQQQLAPGRGKSQLQLRADAFISGLAEARVSEPPV
AAWLALTERYCKAHNLMWHQEFATEHPVQELERLLSAVLIRHQYLGGLVLNALETEVPPP
RQLGEIIRLVHQAKWSVVRTRQQLNRSYKEVCAPILERLRFLLYEVRPAISPQQRGLRRL
PILQRPPRFKMLVRRLLQELRSSRQPAKPEDLLNASIQQEQEKKPQSMPKQELEEQEEEE
TLLRRLNERQIHGEGELDPALMQDIVDFALQDSCDVETARRAMYCQMQRYQLRLAGLQIV
QQLLELHGLLDAAQYSLLNGFLGLHLKSTSSGGGSTGSGSSLHVLGQLNMISAYQKARLL
LAQSRVLDWAVRELRRLVNQEQQGHARGKDSTNLGTYVLLKRLPRARFLLSVFGLLAKEL
GPNELGFLINSGLLGTVLGLLAQTGGEGATGGQVHGELSILYEDSVLKQKSSKAQLSGPD
LAKLMKIGTRIVRGADWKWGDQDGNPPGEGRIISEVGEDGWVRVEWYTGATNSYRMGKEG
QYDLQLADSALNVASPTEPEREDVSGSEASPTSDSHPSKLLRHCAAKLLQILAVGTGLHG
AQLDKDALRGMTSMFRTIIYPKPSMSNISYALGWLNLGFIRAISGDCPRLCLELSTPGWL
SHYLSLLEQPAGNEAGVYRQLHCLRLLQLILAQWGAEEEPRMPALVHQLFATLGRIALHC
PGDASLLPTAEGKARVLLTASHSGSVAEELVALLRRLHTLPSWNPVINSFLAQKLCVAAE
LLAEQSHSTALDSEQVFVLGVLGAMGGHDLRPRVGLHCFHEGSHMVIASFTPKGRCLLAP
GGVGSGVGFVKVQLPAVMPHLDHTVFSLSRLPMNEMLLNAWTVLLYGPAPELRELPSSAD
GRLDLALLRAQQLQMAVLHTNGVLYRHQVALRRILKQRAPGSIYASPDEPDRSDAESQQP
GEQDQQLSSGSGQEPQLLIQCILLRATQASPVKACYSYMDLATAALNCIQSLATQAHQEL
SEGGGVPPNGRALSSPPQPTMVHGVPVYNVARKEQKPSEQVEQKSKWPAAATDAQLIGQI
MEMGFTRRTVELALKQLSLQAEIMPTPEQIVQWILEHPDVCANTIEEDTLPLASSASSHD
PEADSDNECPSSNSTTSSSTSSDTVEGQPMAVSGPAPPVKFESRKDFQTADLYALYVRGL
VRPGMTVRCCRDFEEIKQGDMGTVLIVDTEGLHDLNVQVDWRNHGSTYWVCFVHIELVEA
AQTHHQPRPPPIAVGARVRLRTSSLRYGMLCPLRLGRSQGSSAIGVVSSVRSKQLTVDFP
DQPAWQGHINEVELVASQPTSATLPSLGDSCSQMPPSDLIEDWSRCIRSLTVSSNEAAAK
HLLNGSNQPWQSCSSGPCRHWIRLELHDRILVHSLTLKVSPEDHSHMPSLLEIRVGDCVD
SLKEYTWIPVPAGASRVLLMQQVPTYYPWVEVVVKQCQNNGIQCKIHGIKFVGRRQQPDL
QHILANAQFLASEYSAGVGPGSTAGAGAVSTSHEEAAAAPEQDLPCTVMVWGLNDKEQLG
GLKGSKVKVPTFSQTISRLRPIHIAGGSKSLFIVSQDGKVYACGEGTNGRLGLGVTHNVP
LPHQLPVLRQYVVKKVAVHSGGKHALALTLDGKVFSWGEGEDGKLGHGNRTTLDKPRLVE
ALRAKKIRDVACGSSHSAAISSQGELYTWGLGEYGRLGHGDNTTQLKPKLVTALAGRRVV
QVACGSRDAQTLALTEDGAVFSWGDGDFGKLGRGGSEGSDTPHEIERLSGIGVVQIECGA
QFSLALTRAGEVWTWGKGDYYRLGHGGDQHVRKPQPIGGLRGRRVIHVAVGALHCLAVTD
AGQVYAWGDNDHGQQGSGNTFVNKKPALVIGLDAVFVNRVACGSSHSIAWGLPNASSDEE
KRGPVPFSSTRDPLGGSSLGIYEAETMQTLKQEAKPLNQSSLSESLALETPAARQAALGH
VLRAMSILQARQLIVAALTSHSKVNFKERGAVGGEEDHLIGGPIMGAPLQLAETIAQGGG
EAPADATDAGLQEHSPEAAVDALTGGMSGGANTLPPLSAGPLSAFQSLTGSLSMSGSLSS
SALPQHKHSRMSASAMSVMAATMTQQEEMLSHISHCHGLDDFGGLLGEPEAKSLVELLKL
AVCGRCGPPSTSQTIADTLISLGAGTPAVAAMLLETCITELEDLCTSRHCLGKLPKPVMQ
ESSHPYVDNVNVTGVVRIPGAEMLRLEFDSQCSTEKRNDPLVIMDGTGRVLAMRSGREFA
HWAPEIRVLGDELRWKFSSDSSVNGWGWRFWVHAIMPAATLGESGSDRAVLSQPSMALVM
SLLDSRLAPRQPSVLLRLASALAACSQLGALTTAQRIWSLRKLHAVLLLEQAPRPQDPSL
STLLQPLIPELLRQYEYEEPQVRGGIHLMHSDYFKTLAALACDMQLDAALPATSSSSSSS
AAPGAISSTGDVHKWAWFKRYCIAVRVAQSLIRRTELPRAFCLEVRKKFAEMLPSSSSNS
NANPGCQSPGASMLNSTTSLSSSTVSNVSPPPGITGEQPDLHCHAHQLESTSTLLHEDHT
LFQAPHDAQLLQWLNRRPDDWALSWGGASTIYGWGHNHRGQLGGLEGSRIKTPTPCEALS
LLRPVQLAGGEQSLFAVTPDGKLFATGYGSGGRLGVGGSDSWAIPTLLGSLQHVFVKKVA
VNSGGKHCLALTTEGEVYAWGEGEDGKLGHGNRMSYDRPKLVEHLNGMSVADIACGSAHS
AAITASGHVLTWGKGRYGRLGHGDSEDQLRPKLVEALLGYRAIDIACGSGDAQTLCITDD
DNVWSWGDGDYGKLGRGGSDGCKLPYKIESLAGLGVVKVECGSQFSVALTKSGAVYTWGK
GDFHRLGHGSVDHVRRPKKVAALQGKKIISIATGSLHCVACSDSGEVYTWGDNDEGQLGD
GTVTAIQRPRLVAALQGKHIVKVTCGSAHTLALSTSQLSERLRPLPNPPLEYDLVRDLAP
EALHARLILLHHFSELVCPCLAMLPISGDLSLGALKDVLVYNIKEAAFRKVIQTTMVRDK
QHGPVIELNRIQVKRSRNRCNGLAGIDGMKSVFGQMVQKLPLLTQEALALPHRVWKVKFV
GESVDDCGGGYSESIAEMCDELQNGSVPLLINTPNGRGEAGANRDCFLLDPTLSSVLQMN
MFRFLGVLMGIAVRTGSPLSINLAEPVWRQLTGEVLRPTDLTEVDRDYVAGLLCIRNMDD
DPKLFTALELPFSTSSARGHEVPLSTRYTHISPRNRAEYVRLALGFRLHEFDEQVKAVRD
GMSKVIPVPLLSLFSAAELQAMVCGSPDIPLGLLKSVATYKGFDPSSALVTWFWEVMEEF
TNQERSLFLRFVWGRTRLPRTIADFRGRDFVLQVLEKNPPDHFLPESYTCFFLLKMPRYS
CKAVLLEKLKYAIHFCKSIDTDEYARVAMGEPTEATGSEDNSDLESVASHEG
|
| Download sequence |
 |
| Identical sequences |
Q9VR91
FBpp0290558 NP_608388.2.81976 FBpp0290558 FBpp0290558 |
