The results are sorted from lowest E-value to highest E-value. Strong classifications have a low E-value. Weak classifications have an E-value greater than 0.0001. Weak hits are shown in gray. Weak hits are not shown on the domain architecture.
The family level classification is conditional on the domain being a member of the specified superfamily. There is a possibility that the selected domain is a member of a sub-family for which no structure has yet been solved.
| Sequence: |
FBpp0227212 |
| Domain Number 1 |
Region: 277-422,842-1061,1124-1166 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Ras GEF |
6.15e-109 |
| Family |
Ras GEF |
0.00038 |
| Further Details: |
|
| |
| Domain Number 2 |
Region: 403-488 |
| Classification Level |
Classification |
E-value |
| Superfamily |
PDZ domain-like |
3.94e-17 |
| Family |
PDZ domain |
0.0065 |
| Further Details: |
|
| |
| Domain Number 3 |
Region: 106-231 |
| Classification Level |
Classification |
E-value |
| Superfamily |
cAMP-binding domain-like |
0.00000000000359 |
| Family |
cAMP-binding domain |
0.0018 |
| Further Details: |
|
| |
| Domain Number 4 |
Region: 751-834 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Ubiquitin-like |
0.000000496 |
| Family |
Ras-binding domain, RBD |
0.016 |
| Further Details: |
|
| |
The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by 
(show help)
Information Content (IC) is an information theoretic score measured in bits of how informative it is to assign a given ontological term to a domain archtecture. The higher the score the more informative it is to talk about the term given the domain architecture.
H-score (hypergeometric score) indicates the strength of assigning an ontological term to this domain architecture. Assignments with higher scores are of a better quality. Details for the methodology be found on the dcGO website.
| Biological Process |
IC (bits) |
H-Score |
| Molecular Function |
IC (bits) |
H-Score |
| Cellular Component |
IC (bits) |
H-Score |
| External link(s) |
Protein: FBpp0227212 Gene: FBgn0200031 Transcript: FBtr0228720 |
| Sequence length |
1593 |
| Comment |
type=protein; loc=scaffold_12963:complement(2806053..2806120,2806617..2807144,2807543..2807692,2808071..2811827,2811940..2812188,2812278..2812307); ID=FBpp0227212; name=Dvir\GJ12795-PA; parent=FBgn0200031,FBtr0228720; dbxref=FlyBase:FBpp0227212,FlyBase_Annotation_IDs:GJ12795-PA,GB_protein:EDW63492,REFSEQ:XP_002051337,FlyMine:FBpp0227212; MD5=61a3f44f1c93690b3fd58063e745e4ac; length=1593; release=r1.2; species=Dvir; |
| Sequence |
MDPYHHIRHHYPPTSTAGSTVVGSGTTGSINRPELHQKCNRGSHSSDTSSAYSGSDTMAS
VYGSSLEAEEIDLSGLVESVVDSDEEDLAESMDSLNVRDAVRDCLEKDPSERSEDDVEIL
LEFTQGLKAFTNITLAVRRALCSVMVFAVVDKAGTVVMSDGEELDSWSVLINGAVEIEHA
NGTREELQMGDSFGILPTMDKLYHRGVMRTKCDDCQFVCITQTDYYRIQHQGEENTRRHE
DEQGRIVMVTELRSIGGSGAESATTTGSGSAATAHLNTKRGHVVIRGTPERLLQQLVEEN
SMTDPTYVEDFLLTHRIFIHNPQEVTRKLLHWFDLEQLDSHKTQELRDRVTRVVLLWVNN
HFTDFEADHEMMEFLEIFEAGLESKKLLSQLRLLHIACAAKARMRSCILTRSSRDEPLNF
QIIGGYELRGVAAATGNASVGIYISHVEPGSKAQDVGLKRGDQIHEVNGQSLDHVTSKRA
LELLTGTTHLSIQVKSNLLGFKEIMQALEHGSGSSSAGGGISSTGSGNGSFKSLRSPRRI
CANDIAKLHGRSDSTTEELTNRAHMVRLSSVDMLLDQPDCAPPQTPPVSAGSGNMASNFM
QQLLQSVNSNSAKKCSAEDSKPGGFMTLAPKRRLQKALAKMNLLNKQQQPHVGGSLNDSS
DTLLNEPQSKAKLSAASSGSSSCHSTNGVCTTSGRLYQSQSNPDLSSLNYDNSGEPSATL
QVNYLQAHLHRPSAASTLTSSSMLPPDYPEHVLKVYKSDQTCKYVLIYKETTAHEVVMLT
LQEFGIHDPSSNFSLCEVSVGEGGMVKQRRLPDQLQNLAERISFAARYYLKLNDSTEPLV
PDELALELVRESGVHFLQLNAYELAIQLTLQDFANFRQIESTEYIDELFELQSKYGVPML
SKFSELVNREMFWVVSEICAEHNIVRRMKIVKQFIKIARHCKECRNFNSMFAIISGLGHG
AVSRLRLTWEKLPSKYQRLFNDLQDLMDPSRNMSKYRQLVSAELLAQHPIIPFYPIVKKD
LTFIHLGNDTRVDGLINFEKLRMLSKEVRLLTHMCSSPYDLLAILELKGQTPSNALFSLN
QMSASQSNAAAGTVIAANAGQATIKRRKKSTAAPNPKKMFEEAQMVRRVKAYLNSLKILS
DEDLLHRLSLECEPPHGSTYSGSISHGNSSHRSAGSGSIGGTGGSGGGTGTGSINAGGDQ
LSIYSHTSSSSAPNSSLSLRKRHPSSPTLSTTSSTSSTSDHQRQRQQLHNNGPKFGTASP
QAVKKMLSLSESSKIRPHQPFVPRHSSALPGVIPPLHHLHAAHGFSTPAVSGGGVVAAAA
VSAGVANAQCTPSPSPCAHRRLASGGNILPTRAIHERSHSDTPAPPPPLPSVDLSLESSS
VTTFRDLPLRKSVTSGSVSSCDSGHGSYAQQQQPHHQQHHLTYQQQQQQQQQQQQQQQIA
HNEPSPPVYTAADCRLLQQISNNAVTRNLNSPCQSTSTPPSTPTPPPPTLQQQQQQQQQQ
LAPPPPPTAACIQPPQLPAPPAPYLHMRSHQQLQQIQQQLAMPPPPPPVYTSSLYNHHHS
NATSRHLNHMHGGPPNFMDSTKCTICPMPPMNQ
|
| Download sequence |
 |
| Identical sequences |
B4LQV8
7244.FBpp0227212 FBpp0227212 XP_002051337.1.90633 |
