The results are sorted from lowest E-value to highest E-value. Strong classifications have a low E-value. Weak classifications have an E-value greater than 0.0001. Weak hits are shown in gray. Weak hits are not shown on the domain architecture.
The family level classification is conditional on the domain being a member of the specified superfamily. There is a possibility that the selected domain is a member of a sub-family for which no structure has yet been solved.
Sequence: |
FBpp0263970 |
Domain Number 1 |
Region: 224-344 |
Classification Level |
Classification |
E-value |
Superfamily |
SH2 domain |
3.37e-24 |
Family |
SH2 domain |
0.00075 |
Further Details: |
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Domain Number 2 |
Region: 624-793 |
Classification Level |
Classification |
E-value |
Superfamily |
Ras GEF |
6.15e-23 |
Family |
Ras GEF |
0.02 |
Further Details: |
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Domain Number 3 |
Region: 45-101 |
Classification Level |
Classification |
E-value |
Superfamily |
SAM/Pointed domain |
0.0000000107 |
Family |
SAM (sterile alpha motif) domain |
0.0099 |
Further Details: |
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The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by 
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Information Content (IC) is an information theoretic score measured in bits of how informative it is to assign a given ontological term to a domain archtecture. The higher the score the more informative it is to talk about the term given the domain architecture.
H-score (hypergeometric score) indicates the strength of assigning an ontological term to this domain architecture. Assignments with higher scores are of a better quality. Details for the methodology be found on the dcGO website.
Biological Process |
IC (bits) |
H-Score |
Molecular Function |
IC (bits) |
H-Score |
Cellular Component |
IC (bits) |
H-Score |
External link(s) |
Protein: FBpp0263970 Gene: FBgn0236330 Transcript: FBtr0265478 |
Sequence length |
943 |
Comment |
type=protein; loc=2L:join(13181781..13181838,13181900..13182025,13182083..13182235,13182300..13182471,13183395..13183752,13183822..13184814,13184868..13185302,13185526..13185932,13185991..13186120); ID=FBpp0263970; name=Dyak\GE18960-PA; parent=FBgn0236330,FBtr0265478; dbxref=FlyBase:FBpp0263970,FlyBase_Annotation_IDs:GE18960-PA,GB_protein:EDW88857,REFSEQ:XP_002089145,FlyMine:FBpp0263970; MD5=7ed08d9e8f36a6bdda19ecbafb695e9e; length=943; release=r1.3; species=Dyak; |
Sequence |
MGNTQARQLENRNVPNRRSSILWNFRYSNTVRRREDLAVMVHNSRMSISDWLDLLELQQY
EGNLQEFSIVDDVVDITDKELKQCGVRGAHRQRMVNSLLGVRAKRRQSMNLEAMSSRPRE
VPRRKNSCPLVYLGENPQDMAGSGDSGPAVITTKSGKVLKQLTFDETSTIYEELRPRSKC
NSPHWATEDSRMEGYGSSNATTPLATAQPSPGEQQEAIALKKALEWELSLDARELRSHAW
YHGALPRQRAEEIVQREGDFLVRDCASQPDNYVLSCRSKAAVLHFVLNKLVLQPETVYER
VQYQFEEDAFDTVPDLITFYVGSGKPISSASGALIQYPCNRTYPLSFYGHKIVGNQLHTQ
MLAGLRGLSPLNSPMGSNGAVGAGVAGTFRFEPQQQQQQLSPMAGSPASPHCSPPRARRE
VPPPPRLPCKKQQRSQSLTPAQAMLVSNINKLQEQQLHMQELENGNANGVTRFQTIARCN
PTSEQHLESKFTTHSLPRPNTSAAQALRQHAVARISSLARNCSLDSPSDSRPPSPPPKPR
KEPMAAVLAYQASGSDSGNGSGDSALGDACEASVQRGVIIKNPRFMTTSVSNGTLKSFTE
FDVLAAEEELFTMAIEEVKTASKFDFENFVTLLLPSVENKPLDGDALNTFKMMLLETGPK
LLAEHITRIDIALFLEEPSNEEDYYLSCSGLELLTLPHGRVFREDIIERTQCIKLMVAVT
ILTCQTDLDRAQLLSKWIQIAVETKTALGNLFGFCAIMLGLCMQQIQKLDQAWHILRQQY
TDSAFTFEAKLRPTLSIMNEASNPQAPNTTVPHVLLYALLIDRPVMDIINHSNIDDRPAL
YHTCIAPWESKADDFGMTINFQHLDASRGFLKNLELYRKNAKIILEDASPRLDELLADAF
RTEFHVKFLWGSSGATAKAEDRHNKLEKVLTLMADKFCMMAEQ
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Download sequence |
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Identical sequences |
B4NZS3
XP_002089145.1.41174 FBpp0263970 7245.FBpp0263970 |