SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.

  Home > Genomes > Erinaceus europaeus 76 > ENSEEUP00000011877

Domain assignment for ENSEEUP00000011877 from Erinaceus europaeus 76

Domain architecture

Domain assignment details

(show help)
Strong hits

Sequence:  ENSEEUP00000011877
Domain Number 1 Region: 5225-5346
Classification Level Classification E-value
Superfamily PH domain-like 1.42e-32
Family Pleckstrin-homology domain (PH domain) 0.00069
Further Details:      
 
Domain Number 2 Region: 4985-5213
Classification Level Classification E-value
Superfamily DBL homology domain (DH-domain) 1.44e-29
Family DBL homology domain (DH-domain) 0.00034
Further Details:      
 
Domain Number 3 Region: 222-320,3859-3954
Classification Level Classification E-value
Superfamily Fibronectin type III 1.57e-29
Family Fibronectin type III 0.0007
Further Details:      
 
Domain Number 4 Region: 4463-4555
Classification Level Classification E-value
Superfamily Immunoglobulin 2.67e-23
Family I set domains 0.006
Further Details:      
 
Domain Number 5 Region: 5350-5448
Classification Level Classification E-value
Superfamily Immunoglobulin 8.08e-22
Family I set domains 0.0037
Further Details:      
 
Domain Number 6 Region: 1768-1861
Classification Level Classification E-value
Superfamily Immunoglobulin 7.16e-19
Family I set domains 0.011
Further Details:      
 
Domain Number 7 Region: 4239-4332
Classification Level Classification E-value
Superfamily Immunoglobulin 4.8e-18
Family I set domains 0.0047
Further Details:      
 
Domain Number 8 Region: 2249-2342
Classification Level Classification E-value
Superfamily Immunoglobulin 5.08e-18
Family I set domains 0.018
Further Details:      
 
Domain Number 9 Region: 3145-3232
Classification Level Classification E-value
Superfamily Immunoglobulin 6.57e-18
Family I set domains 0.046
Further Details:      
 
Domain Number 10 Region: 4599-4694
Classification Level Classification E-value
Superfamily Immunoglobulin 8.06e-18
Family I set domains 0.0041
Further Details:      
 
Domain Number 11 Region: 858-954
Classification Level Classification E-value
Superfamily Immunoglobulin 1.13e-17
Family I set domains 0.011
Further Details:      
 
Domain Number 12 Region: 766-863
Classification Level Classification E-value
Superfamily Immunoglobulin 1.44e-17
Family I set domains 0.013
Further Details:      
 
Domain Number 13 Region: 2435-2520
Classification Level Classification E-value
Superfamily Immunoglobulin 2.94e-17
Family I set domains 0.0072
Further Details:      
 
Domain Number 14 Region: 1042-1138
Classification Level Classification E-value
Superfamily Immunoglobulin 8.71e-17
Family I set domains 0.011
Further Details:      
 
Domain Number 15 Region: 2071-2164
Classification Level Classification E-value
Superfamily Immunoglobulin 2.09e-16
Family I set domains 0.012
Further Details:      
 
Domain Number 16 Region: 2875-2968
Classification Level Classification E-value
Superfamily Immunoglobulin 2.24e-16
Family I set domains 0.07
Further Details:      
 
Domain Number 17 Region: 3057-3146
Classification Level Classification E-value
Superfamily Immunoglobulin 3.25e-16
Family I set domains 0.035
Further Details:      
 
Domain Number 18 Region: 1134-1230
Classification Level Classification E-value
Superfamily Immunoglobulin 3.67e-16
Family I set domains 0.01
Further Details:      
 
Domain Number 19 Region: 3227-3320
Classification Level Classification E-value
Superfamily Immunoglobulin 5.36e-16
Family I set domains 0.023
Further Details:      
 
Domain Number 20 Region: 1227-1322
Classification Level Classification E-value
Superfamily Immunoglobulin 8.58e-16
Family I set domains 0.012
Further Details:      
 
Domain Number 21 Region: 3316-3410
Classification Level Classification E-value
Superfamily Immunoglobulin 0.00000000000000104
Family I set domains 0.031
Further Details:      
 
Domain Number 22 Region: 692-774
Classification Level Classification E-value
Superfamily Immunoglobulin 0.00000000000000127
Family I set domains 0.0094
Further Details:      
 
Domain Number 23 Region: 951-1047
Classification Level Classification E-value
Superfamily Immunoglobulin 0.00000000000000171
Family I set domains 0.015
Further Details:      
 
Domain Number 24 Region: 3411-3501
Classification Level Classification E-value
Superfamily Immunoglobulin 0.00000000000000196
Family I set domains 0.018
Further Details:      
 
Domain Number 25 Region: 5439-5521
Classification Level Classification E-value
Superfamily Immunoglobulin 0.00000000000000244
Family I set domains 0.017
Further Details:      
 
Domain Number 26 Region: 1416-1504
Classification Level Classification E-value
Superfamily Immunoglobulin 0.00000000000000296
Family I set domains 0.022
Further Details:      
 
Domain Number 27 Region: 1506-1577
Classification Level Classification E-value
Superfamily Immunoglobulin 0.00000000000000423
Family I set domains 0.055
Further Details:      
 
Domain Number 28 Region: 2794-2882
Classification Level Classification E-value
Superfamily Immunoglobulin 0.0000000000000117
Family V set domains (antibody variable domain-like) 0.059
Further Details:      
 
Domain Number 29 Region: 2619-2708
Classification Level Classification E-value
Superfamily Immunoglobulin 0.0000000000000304
Family I set domains 0.016
Further Details:      
 
Domain Number 30 Region: 33-124
Classification Level Classification E-value
Superfamily Immunoglobulin 0.0000000000000441
Family I set domains 0.011
Further Details:      
 
Domain Number 31 Region: 2698-2773
Classification Level Classification E-value
Superfamily Immunoglobulin 0.0000000000000536
Family I set domains 0.023
Further Details:      
 
Domain Number 32 Region: 4708-4800
Classification Level Classification E-value
Superfamily Immunoglobulin 0.00000000000013
Family I set domains 0.04
Further Details:      
 
Domain Number 33 Region: 2517-2611
Classification Level Classification E-value
Superfamily Immunoglobulin 0.000000000000526
Family I set domains 0.016
Further Details:      
 
Domain Number 34 Region: 2972-3058
Classification Level Classification E-value
Superfamily Immunoglobulin 0.00000000000107
Family I set domains 0.048
Further Details:      
 
Domain Number 35 Region: 3497-3592
Classification Level Classification E-value
Superfamily Immunoglobulin 0.00000000000187
Family I set domains 0.019
Further Details:      
 
Domain Number 36 Region: 2169-2259
Classification Level Classification E-value
Superfamily Immunoglobulin 0.0000000000021
Family I set domains 0.012
Further Details:      
 
Domain Number 37 Region: 3778-3864
Classification Level Classification E-value
Superfamily Immunoglobulin 0.0000000000025
Family I set domains 0.0058
Further Details:      
 
Domain Number 38 Region: 3969-4040
Classification Level Classification E-value
Superfamily Immunoglobulin 0.00000000000272
Family I set domains 0.015
Further Details:      
 
Domain Number 39 Region: 3587-3681
Classification Level Classification E-value
Superfamily Immunoglobulin 0.00000000000869
Family I set domains 0.0071
Further Details:      
 
Domain Number 40 Region: 3684-3773
Classification Level Classification E-value
Superfamily Immunoglobulin 0.0000000000733
Family I set domains 0.02
Further Details:      
 
Domain Number 41 Region: 320-364,429-483
Classification Level Classification E-value
Superfamily Immunoglobulin 0.000000000213
Family I set domains 0.015
Further Details:      
 
Domain Number 42 Region: 1689-1775
Classification Level Classification E-value
Superfamily Immunoglobulin 0.000000000287
Family I set domains 0.01
Further Details:      
 
Domain Number 43 Region: 4939-5002
Classification Level Classification E-value
Superfamily SH3-domain 0.0000000129
Family SH3-domain 0.0038
Further Details:      
 
Domain Number 44 Region: 1358-1416
Classification Level Classification E-value
Superfamily Immunoglobulin 0.0000000155
Family I set domains 0.033
Further Details:      
 
Domain Number 45 Region: 1596-1665
Classification Level Classification E-value
Superfamily Immunoglobulin 0.000000291
Family I set domains 0.018
Further Details:      
 
Weak hits

Sequence:  ENSEEUP00000011877
Domain Number - Region: 2-42
Classification Level Classification E-value
Superfamily Immunoglobulin 0.000999
Family I set domains 0.05
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

(show help)

Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) Protein: ENSEEUP00000011877   Gene: ENSEEUG00000012792   Transcript: ENSEEUT00000013034
Sequence length 5935
Comment pep:known_by_projection genescaffold:HEDGEHOG:GeneScaffold_5948:2554:118562:1 gene:ENSEEUG00000012792 transcript:ENSEEUT00000013034 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence 
NFVLQILFCNQSDRGLYPCTASNLVGPTYSSVLVVVSEPAVPFTKRLQDLEVREKESATF
RCEVAQPATQAAWFKEETRLWASAKYGIEEAGTERRLTVHNISADDDAVYICETTEGSRT
VAELSVQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPRKPPLHAPEGPVVKSRTEGSVTLA
WSPPPRGVTIDGYLVEKRRLGAYAWSRCHEMEWVATTELTVSGVTQEGDFQFRVSAVNSF
GQSPYVEFPGTIHLTPQLAVKTPLKAMEIVEGGEVTFSVDLSLVSVGEWFLDGRALKSSS
MYVIQCDGTRHALTIRRVPASLHGAELKFMANGIESSIKMEVRAAPGLSPKHPTAAREVL
ARLHEEAELLALSDQAAAVTWLKDGRALPPGPKYEVQAVAGRRVLLVWDVVRDDAGLYEC
IIRGNHLAYQLSVQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXPKVVFAKEQQARSEVQAEAGASATLNCQVAQAQTEVTWYKD
GKKLTSSSKVRVEAQGCSRRLVVQQAGKADAGEYSCEAGGQKVSFCLDVKEPKVVFAKEQ
QASSEVQAEAGASVTLRCEVAQAQTEVTWYKDGKKLSSSSRVRVEAQGCSRRLVVQQAGK
ADAGEYSCEAGGQKVSFHLDVKEPKVVFAKEQQARSEVQAEAGASATLSCQVSQAQTEVT
WYKDGKKLSSSSKVRVEAQGCSRRLVVQQAGKADAGEYSCEAGGQKVSFSLDVKETKVLF
ARNQQAHSEVQAEAGASATLSCEVAQTQTEVTWYKDGKKLSSSFQVRVEAQGCSRRLVVQ
QAGKADAGEYSCEAGAQKVSFHLDVTEPKMVFAKEQQAHSEVQAEAGASAILSCEVAQTQ
TEVTWYKDGKKLTSSSRVRVEAQGCSRRLVVQQAGKADAGEYSCEAGGQKVSFHLDVKEA
KVVFAKEQQASSEVQSEAGASATLSCEVAQTQTEVTWYKDGKKLSSSSKVRVEAHGCSRR
LVVQQAGKADAGEYSCEAGGQKVSFCLDVKEAKVVFAKEQQASSEVQSEAGASATLSCEV
AQTQTEVTWYKDGKKLSSSSKVRVEAHGCSRRLVVQQAGKADAGEYSCEAGGQKVSFCLD
VKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAAVTWLKDGMEIRRSKRHETASR
GNKHTLTVHGAQTLDSAIYSCRVGEQGQDFPVQVEEVAAKFSQPLAPVSGELGGTVTLAC
ELSPAQAEVVWRCGSMQLRPGKRFQMVADGPRRLLTVSGLRAEDAGEYVCESREDRTSAQ
LTVSVPREVKFTSGLSAVTAEEGCEATFQCVVSPSDVVVTWFRDGTQLQPSGKFVMSQSG
SSHSLTISDLTLEDAGQIXXXXXXXXXXXXXXXXXAPVLFKKKLEPQTVEELSSVTMEVE
LTRPWPEVKWTRNAAILSSGGNVEIQAENVSHRLILHSVGFTDRGFXXXXXXXXXXXXXX
XXXXRQVRLVRGLQEVEAQEQGTATMEVELSHVDVEGSWIKDGLRLQPGPTCHLAVRGTT
HTLTLSGLQPKDAGLVGFKAEGVHTSARLVVTELPVRFSRPLQDVMVTEKDKMTLECELS
RPNVDVRWLKDGVELRAGKKVGIMAQGACRSLVIYRCELGDQGVYVCDAHDAQSSASVKV
QXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
GTVHRLKLRRTCSTMTGPVHFTIGKSRSTARLVVSDIPVVLTRPLEPKVGREQQSVVLSC
DFKPPPKAVQWYKGDMPLAPSKKYKMNLEGHMAKLRVLRLTSADAGIYRCQAGSAQSSAE
VTVEAREVSVTQPLQDVEATEEGRACFSCELSHEDEEVEWLLNGTPLYNDSFHEISHQGH
RHTLVLKRVRQADAGILQVSSPKITASARLQVKEKPVVFLKALDDVSAEEQGTLALQCEV
SNREARVLWRKDGVELGPSDKYDFLHSAATRGLVVHDLNKDDAGIYTCHVGAEQTQARVS
VHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRPVDFSKPLEDQQVARGEDVTLSCEL
SQSGALVRWLRDGKAIRRSRKYEVLTEGTRAVLIIRAASIKDSGEYTCETEASKSTAHLR
VEEKANRFTEELADLQLEEKGTAVFQCKTEHPTATVIWRKGLLELRASGKYSFSQEGLTL
KLTISALEKVDSDTYTCDIAQARSQARLLVQGQKVLISEDLEDVEVQEGSSATFCCRISP
SDYGPVHWFLDKTPLHTNELNEIEARPGGYHMLTLRQLTLKDSGTVHFEAGDQRASANLQ
VTEKPSIFSRELMDVTVTEGEELTLVCETTAPDSSVSWTKDGKTLRSSVRCRLSHEGSRV
QLVITGATLQDGGXXXXXXXXXXXXXXXXXXXRPVHFREGLKDLEVQEGGAATLRCVLSS
VAPVEWRRGDEVLRAGGKYSLRQEGAVLELVVRDLRPLDSGQYSCCFGDQVTLATLTVKA
QPAEFIGRLRSKEATEGTTATLRCELTKEAPVEWRKGSETLTTKERVILRQDGAVCELQI
SGLTLEDAGEYTCVCGQERTSATLTIRVLTVKFTNTVRKEESTEGSTATLNCELSKEAPV
EWRKGSETLTTNDKVGLRQAGAMCELQIHGLTVEDAGEYLCMCGQERTLAILTIRALPAK
FTKSLRKEEATEGATAMLCCELSKVAPVEWKKGSEILKAGDRISLKHDGTMCELQIHDLA
MEDAGEYSCVCGQERTSATLTIRVLPAKFTRGLKNEETTEGTTVTLHCELSKEAPVEWRK
GSETLTPNDRVSLRQDGTLCELQIHSLTVEDAGEYSCVCGQERTSATLTIRAPQVGFREP
LQSIQAEEGTSAYLRCELWEPSATVVWSKGGLELQADERLEPRRRGTTAELVLRELRRED
SGEYSCACGTQTTSATLSITAAPVRFLRELQAQEVDEGGIARLHCELSREGASVEWRKGS
LQLFPCAKYQMVQEGTLAELLVHDVELEDAGHYTCDTGHTQSTAVLSVQVPRPKFKTELQ
SAEQEAGGVARLQCQLSDSEPGAPVQWLKEGVELHSGPKYEIRRQGATCELLVHRLEAKD
TGEYACMVGSQKTLASIKVKEAEVTIVRGLVDAEVQADGDVEFSCEVSRAGARGVQWRLQ
GLPLQNNEVTEVTMQGDCTHILRLKGVTPEDTGTVSFHVGIHSSSAQLTVQVPEVIILEP
LKDLQLGEGQDAHFQCRLSRTVGQEARWALGGVPLQANEMNDITVEQGVLHSLTLHKVTL
EDAGTVSFQVGSCSSQAQLKITAKNKVVRGLENVEAPEGGEALFECQLAQPEVAVHTWLL
DDEPVRTSDRAEVVYFEDGRRHLLLLKNLQPQDSCQVTFLAGDLVTSAFLTVRGWRLEVL
EPPQDVSVHVGAQARFSCMLSEVVPVGEATWYINGAAVQPDNTDWKVTADGNHHGLLLHS
AQLHHSGEVTFAARDAVVTAQLSVMGLPDPPEDAEVVGRSDRSVTLSWAAPMSDGGGGLC
GYRVEMKAAATGEWQLCHELVPGPECVVDDLAPGETYRFRVAAVSPVGAGEPVHLPQMVK
LAEPLEPKPTPQAPETRQVVVGEDLCLECEVTEAGEVIWLKGTERVQPSGRFQVLCEGRR
QTLVIRGFTAEDQGEYRCSPTQGPAPAAFQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAGPPAAPSVKPQKQPVQPAAVSPSPL
GELSAEDLGDPSMDKAAMKIQAAFKGYKVRKEIKQQEGPVFCRTFGDTEAQVGDVLCLEC
VVSSKVDVRACWLKDGMELTDSRHHHIDQLADGTCSLLVTGLGREDAGRYTCQVRSKFGQ
VSHSAQVAVSGTESEAESSSGGERDDTFHRAARRLHRLFRTKGPAEVSDEEIFLSADEGP
AEPEGPSNWSTYREDEHSVCIHFEALAEAQQAAARFQEMFGTLGIQVETRLSEQGPRGVE
VHIGKVALAQGAPPAPSPLSTEAAPVFLTELKNQEVLDGYPVSFDCVVTGQPVPSVRWFK
DGRVLEEDDHYMISDDQQGGHQLIITAVVPADMGVYRCLAENSVGVSSTKAELRVDLTST
DYDTAADATETSSYFSAQGYLSSREQEGTESTSEEGQLPQVVEELKDLEVAPGTLLAKFQ
LKVKGYPVPRLYWFKDGQPLTASEHIRMTDRKTLHSLEVLSVTREDAGQYSAYISNSVGA
AYSSARLLVRGPNDPEDRLAADVQQHLVPPRILERFTSKKVKKGSSITFSVKVEGCPAPT
VHWLREEAGRGVLWIGRDTPGYTVASSAQQHSLVLLDVGPQHRGTYTCITNAAGQALCSA
LHISGXXXXXXXXXEVKAALISSFLQGAQAVSAQMVVGSAGLADLAVQRKGEAPTMEETR
GHLSLAEVGTEEFLQRLTSQITEMVSAKITQAKLQVPGGDSDEESKTPSASPRHGRSRPS
SSIQESSSESEDGDSRGEIFDIYVVTADYLPLGAEPDAITLREGQYVEVLDSAHPLRWLV
RTKPTKSSPSRQGWVSPAYLDRRLKLSPEWGPTEAPEFPREAVSEDEYKTRLSSTIKELL
SSEQAFVDKLQFLESHHMQHLDHSAHVPSAVASQRDVIFRNVKDISHFHSSFLQELQGCD
TDDDVAMCFIKNQAAFEKYLEFLVGRVQAESVVVSTAVQEFYKKYTEEVLSADPSQPPPP
PLQHFLEQPVERVQQYQALLKELIRNKARNRQACAMLEQAYAVVSALPRRAEDRLHVSLM
ENYPGTLEALGEPIRQGHFIVWEGAPGARMPWKGHHRHVFLFRNHLVVCKPKRDSRTDTF
SYVFRNMMKLSSIDLNEQVEGDDRAFEVWHEREDSVRKYLLQARTATTKNSWVKEIRGIQ
QRLALPIWRAPDFEEELADCTAELGETVKLACRVTGTPTPVVSWYKDGKPVEVDPHHIFI
EDPDGSCALILDNLTGADSGQYMCFAASAAGNASTLGKILVQVPPYFVNKVRALPFVEGE
DAQVTCSFEGAPYPQIRWYKDGSLLTPGGKYRTLSEPRSGVLVLEIRAACAEDLGHYECE
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTEQETRVPKKTVIIEETITTVV
KSPRGRRPSPSKSPARSPSRLPASPPRPSPLGSEPRYPQGAGQPCRPEAEPGRRPPVPML
YITEAEARTPAQPRGTGPHPKWVEVEETIEVRVKKAGLGSTAPAGEVPGSPTGLLFTLPG
GTSGGDPNTNNSNNKLLAQEPRAGDRAKVTTDEPLVFHVDVARAAPAITSLDCEEETLLE
EEEEPQDAEGLWGRDPKILTHNGRAMTLADLDDYVPQAGETFGCLRPGHGPSNDPPCEVA
VLQREIREPTVGQPVLLNVGHPAGFFGHSARPQGASPSGPQVRGPVGVSFSVREARVGAT
AAWKPSFCTHIQRSMDSGQSSFKTEVSTQTLGFGTLGETVTLHIHPDEDGAKQRW
Download sequence
Identical sequences ENSEEUP00000011877 ENSEEUP00000011877

Jump to [ Top of page · Domain architecture · Domain assignment details · Most Informative Gene Ontologies ]
Please cite: Gough, J., Karplus, K., Hughey, R. and Chothia, C. (2001). "Assignment of Homology to Genome Sequences using a Library of Hidden Markov Models that Represent all Proteins of Known Structure." J. Mol. Biol., 313(4), 903-919.

Please send feedback, comments or questions to superfamily@cs.bris.ac.uk or use the feedback form.

© Copyright 2013 The SUPERFAMILY authors and Julian Gough.