The results are sorted from lowest E-value to highest E-value. Strong classifications have a low E-value. Weak classifications have an E-value greater than 0.0001. Weak hits are shown in gray. Weak hits are not shown on the domain architecture.
The family level classification is conditional on the domain being a member of the specified superfamily. There is a possibility that the selected domain is a member of a sub-family for which no structure has yet been solved.
| Sequence: |
ENSGACP00000002355 |
| Domain Number 1 |
Region: 1118-1340 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Kelch motif |
3.92e-34 |
| Family |
Kelch motif |
0.0038 |
| Further Details: |
|
| |
| Domain Number 2 |
Region: 1035-1105 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Kelch motif |
0.000000772 |
| Family |
Kelch motif |
0.035 |
| Further Details: |
|
| |
| Domain Number 3 |
Region: 607-642 |
| Classification Level |
Classification |
E-value |
| Superfamily |
EGF/Laminin |
0.00000117 |
| Family |
EGF-type module |
0.014 |
| Further Details: |
|
| |
| Domain Number 4 |
Region: 742-791 |
| Classification Level |
Classification |
E-value |
| Superfamily |
EGF/Laminin |
0.00000195 |
| Family |
Laminin-type module |
0.005 |
| Further Details: |
|
| |
| Domain Number 5 |
Region: 831-935 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Spermadhesin, CUB domain |
0.00000329 |
| Family |
Spermadhesin, CUB domain |
0.0049 |
| Further Details: |
|
| |
| Domain Number 6 |
Region: 1731-1781 |
| Classification Level |
Classification |
E-value |
| Superfamily |
EGF/Laminin |
0.0000117 |
| Family |
Laminin-type module |
0.015 |
| Further Details: |
|
| |
| Domain Number 7 |
Region: 1652-1699 |
| Classification Level |
Classification |
E-value |
| Superfamily |
EGF/Laminin |
0.0000542 |
| Family |
EGF-like domain of nidogen-1 |
0.081 |
| Further Details: |
|
| |
The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by 
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Information Content (IC) is an information theoretic score measured in bits of how informative it is to assign a given ontological term to a domain archtecture. The higher the score the more informative it is to talk about the term given the domain architecture.
H-score (hypergeometric score) indicates the strength of assigning an ontological term to this domain architecture. Assignments with higher scores are of a better quality. Details for the methodology be found on the dcGO website.
| Biological Process |
IC (bits) |
H-Score |
| Molecular Function |
IC (bits) |
H-Score |
| Cellular Component |
IC (bits) |
H-Score |
