The results are sorted from lowest E-value to highest E-value. Strong classifications have a low E-value. Weak classifications have an E-value greater than 0.0001. Weak hits are shown in gray. Weak hits are not shown on the domain architecture.
The family level classification is conditional on the domain being a member of the specified superfamily. There is a possibility that the selected domain is a member of a sub-family for which no structure has yet been solved.
| Sequence: |
ENSP00000421148 |
| Domain Number 1 |
Region: 913-1088 |
| Classification Level |
Classification |
E-value |
| Superfamily |
GTPase activation domain, GAP |
3.34e-37 |
| Family |
BCR-homology GTPase activation domain (BH-domain) |
0.00052 |
| Further Details: |
|
| |
| Domain Number 2 |
Region: 490-606 |
| Classification Level |
Classification |
E-value |
| Superfamily |
ArfGap/RecO-like zinc finger |
4.71e-32 |
| Family |
Pyk2-associated protein beta ARF-GAP domain |
0.0018 |
| Further Details: |
|
| |
| Domain Number 3 |
Region: 284-380 |
| Classification Level |
Classification |
E-value |
| Superfamily |
PH domain-like |
3.29e-24 |
| Family |
Pleckstrin-homology domain (PH domain) |
0.00045 |
| Further Details: |
|
| |
| Domain Number 4 |
Region: 1174-1321 |
| Classification Level |
Classification |
E-value |
| Superfamily |
PH domain-like |
2.02e-18 |
| Family |
Pleckstrin-homology domain (PH domain) |
0.042 |
| Further Details: |
|
| |
| Domain Number 5 |
Region: 8-64 |
| Classification Level |
Classification |
E-value |
| Superfamily |
SAM/Pointed domain |
0.000000000000412 |
| Family |
SAM (sterile alpha motif) domain |
0.0043 |
| Further Details: |
|
| |
| Domain Number 6 |
Region: 605-783 |
| Classification Level |
Classification |
E-value |
| Superfamily |
PH domain-like |
0.00000000000168 |
| Family |
Pleckstrin-homology domain (PH domain) |
0.023 |
| Further Details: |
|
| |
| Domain Number 7 |
Region: 391-500 |
| Classification Level |
Classification |
E-value |
| Superfamily |
PH domain-like |
0.0000000000176 |
| Family |
Pleckstrin-homology domain (PH domain) |
0.022 |
| Further Details: |
|
| |
| Domain Number 8 |
Region: 798-906 |
| Classification Level |
Classification |
E-value |
| Superfamily |
PH domain-like |
0.00000011 |
| Family |
Pleckstrin-homology domain (PH domain) |
0.024 |
| Further Details: |
|
| |
| Domain Number 9 |
Region: 1131-1194 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Ubiquitin-like |
0.00000313 |
| Family |
Ras-binding domain, RBD |
0.062 |
| Further Details: |
|
| |
The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by 
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Information Content (IC) is an information theoretic score measured in bits of how informative it is to assign a given ontological term to a domain archtecture. The higher the score the more informative it is to talk about the term given the domain architecture.
H-score (hypergeometric score) indicates the strength of assigning an ontological term to this domain architecture. Assignments with higher scores are of a better quality. Details for the methodology be found on the dcGO website.
| Cellular Component |
IC (bits) |
H-Score |
| Biological Process |
IC (bits) |
H-Score |
| Molecular Function |
IC (bits) |
H-Score |
