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Domain assignment for ENSP00000442812 from Homo sapiens 69_37

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSP00000442812
Domain Number 1 Region: 349-543
Classification Level Classification E-value
Superfamily GTPase activation domain, GAP 8.83e-58
Family BCR-homology GTPase activation domain (BH-domain) 0.00000000418
Further Details:      
 
Domain Number 2 Region: 99-234
Classification Level Classification E-value
Superfamily SH2 domain 8.08e-27
Family SH2 domain 0.0000000867
Further Details:      
 
Domain Number 3 Region: 279-343
Classification Level Classification E-value
Superfamily Cysteine-rich domain 6.88e-18
Family Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) 0.0000369
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) Protein: ENSP00000442812   Gene: ENSG00000106069   Transcript: ENST00000546235
Sequence length 543
Comment pep:known chromosome:GRCh37:7:29237357:29552603:1 gene:ENSG00000106069 transcript:ENST00000546235 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MTQTHRAKSASSCPNLLVPETWPHQVSASHAGRSKQPQGGILKINEEHRRGAIQDLLASP
GFTFGKRVVFDSHCLKRQHTFADGLHSSCTSNAEEYQPPIWKSYLYQLQQEAPRPKRIIC
PREVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNY
RLFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREK
VSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGP
HWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKA
HNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDI
NIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRY
LMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENED
VLF
Download sequence
Identical sequences ENSP00000444063 ENSP00000442812

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