The results are sorted from lowest E-value to highest E-value. Strong classifications have a low E-value. Weak classifications have an E-value greater than 0.0001. Weak hits are shown in gray. Weak hits are not shown on the domain architecture.
The family level classification is conditional on the domain being a member of the specified superfamily. There is a possibility that the selected domain is a member of a sub-family for which no structure has yet been solved.
| Sequence: |
ENSDORP00000004406 |
| Domain Number 1 |
Region: 5-135 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Concanavalin A-like lectins/glucanases |
4.19e-18 |
| Family |
Clostridium neurotoxins, the second last domain |
0.034 |
| Further Details: |
|
| |
| Domain Number 2 |
Region: 226-346,411-478 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Metalloproteases ("zincins"), catalytic domain |
0.00000000000000234 |
| Family |
Reprolysin-like |
0.067 |
| Further Details: |
|
| |
| Domain Number 3 |
Region: 358-519 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Metalloproteases ("zincins"), catalytic domain |
0.0000000000265 |
| Family |
Reprolysin-like |
0.085 |
| Further Details: |
|
| |
| Domain Number 4 |
Region: 1207-1279 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Complement control module/SCR domain |
0.00000000306 |
| Family |
Complement control module/SCR domain |
0.003 |
| Further Details: |
|
| |
| Sequence: |
ENSDORP00000004406 |
| Domain Number - |
Region: 1271-1306 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Complement control module/SCR domain |
0.000373 |
| Family |
Complement control module/SCR domain |
0.0079 |
| Further Details: |
|
| |
| Domain Number - |
Region: 1071-1110 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Complement control module/SCR domain |
0.00057 |
| Family |
Complement control module/SCR domain |
0.0075 |
| Further Details: |
|
| |
| Domain Number - |
Region: 1183-1212 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Complement control module/SCR domain |
0.00311 |
| Family |
Complement control module/SCR domain |
0.0081 |
| Further Details: |
|
| |
The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by 
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Information Content (IC) is an information theoretic score measured in bits of how informative it is to assign a given ontological term to a domain archtecture. The higher the score the more informative it is to talk about the term given the domain architecture.
H-score (hypergeometric score) indicates the strength of assigning an ontological term to this domain architecture. Assignments with higher scores are of a better quality. Details for the methodology be found on the dcGO website.
| Cellular Component |
IC (bits) |
H-Score |
| Biological Process |
IC (bits) |
H-Score |
| Molecular Function |
IC (bits) |
H-Score |
