SUPERFAMILY 1.75 HMM library and genome assignments server

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Domain assignment for XP_001899725.1.25112 from NCBI 2017_08 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  XP_001899725.1.25112
Domain Number 1 Region: 3212-3318
Classification Level Classification E-value
Superfamily Cadherin-like 1.07e-28
Family Cadherin 0.00068
Further Details:      
 
Domain Number 2 Region: 1011-1145
Classification Level Classification E-value
Superfamily Cadherin-like 2.28e-25
Family Cadherin 0.0007
Further Details:      
 
Domain Number 3 Region: 2700-2823
Classification Level Classification E-value
Superfamily Cadherin-like 5.57e-25
Family Cadherin 0.001
Further Details:      
 
Domain Number 4 Region: 695-808
Classification Level Classification E-value
Superfamily Cadherin-like 1.33e-24
Family Cadherin 0.0014
Further Details:      
 
Domain Number 5 Region: 3731-3920
Classification Level Classification E-value
Superfamily Concanavalin A-like lectins/glucanases 4.91e-22
Family Laminin G-like module 0.0057
Further Details:      
 
Domain Number 6 Region: 1977-2086
Classification Level Classification E-value
Superfamily Cadherin-like 7.57e-22
Family Cadherin 0.0015
Further Details:      
 
Domain Number 7 Region: 796-915
Classification Level Classification E-value
Superfamily Cadherin-like 4.85e-21
Family Cadherin 0.0029
Further Details:      
 
Domain Number 8 Region: 3113-3217
Classification Level Classification E-value
Superfamily Cadherin-like 8.85e-20
Family Cadherin 0.0015
Further Details:      
 
Domain Number 9 Region: 909-1026
Classification Level Classification E-value
Superfamily Cadherin-like 7.14e-19
Family Cadherin 0.0029
Further Details:      
 
Domain Number 10 Region: 2187-2285
Classification Level Classification E-value
Superfamily Cadherin-like 1.16e-18
Family Cadherin 0.0012
Further Details:      
 
Domain Number 11 Region: 1122-1219
Classification Level Classification E-value
Superfamily Cadherin-like 6.28e-18
Family Cadherin 0.0014
Further Details:      
 
Domain Number 12 Region: 2085-2192
Classification Level Classification E-value
Superfamily Cadherin-like 7e-17
Family Cadherin 0.0019
Further Details:      
 
Domain Number 13 Region: 1436-1567
Classification Level Classification E-value
Superfamily Cadherin-like 2.2e-16
Family Cadherin 0.0049
Further Details:      
 
Domain Number 14 Region: 2492-2597
Classification Level Classification E-value
Superfamily Cadherin-like 4.85e-16
Family Cadherin 0.0038
Further Details:      
 
Domain Number 15 Region: 2399-2503
Classification Level Classification E-value
Superfamily Cadherin-like 0.00000000000000113
Family Cadherin 0.0071
Further Details:      
 
Domain Number 16 Region: 139-227
Classification Level Classification E-value
Superfamily Cadherin-like 0.000000000000005
Family Cadherin 0.0022
Further Details:      
 
Domain Number 17 Region: 3314-3430
Classification Level Classification E-value
Superfamily Cadherin-like 0.00000000000000642
Family Cadherin 0.0028
Further Details:      
 
Domain Number 18 Region: 3010-3120
Classification Level Classification E-value
Superfamily Cadherin-like 0.00000000000000728
Family Cadherin 0.0017
Further Details:      
 
Domain Number 19 Region: 1637-1715,1743-1783
Classification Level Classification E-value
Superfamily Cadherin-like 0.0000000000000286
Family Cadherin 0.0032
Further Details:      
 
Domain Number 20 Region: 461-579
Classification Level Classification E-value
Superfamily Cadherin-like 0.00000000000143
Family Cadherin 0.0078
Further Details:      
 
Domain Number 21 Region: 1771-1898
Classification Level Classification E-value
Superfamily Cadherin-like 0.0000000000214
Family Cadherin 0.0061
Further Details:      
 
Domain Number 22 Region: 373-465
Classification Level Classification E-value
Superfamily Cadherin-like 0.0000000000443
Family Cadherin 0.0076
Further Details:      
 
Domain Number 23 Region: 2603-2705
Classification Level Classification E-value
Superfamily Cadherin-like 0.0000000000585
Family Cadherin 0.0073
Further Details:      
 
Domain Number 24 Region: 1886-1989
Classification Level Classification E-value
Superfamily Cadherin-like 0.000000000443
Family Cadherin 0.0015
Further Details:      
 
Domain Number 25 Region: 592-696
Classification Level Classification E-value
Superfamily Cadherin-like 0.00000000186
Family Cadherin 0.0063
Further Details:      
 
Domain Number 26 Region: 2804-2933
Classification Level Classification E-value
Superfamily Cadherin-like 0.00000000443
Family Cadherin 0.0083
Further Details:      
 
Domain Number 27 Region: 3959-4000
Classification Level Classification E-value
Superfamily EGF/Laminin 0.0000000466
Family EGF-type module 0.0085
Further Details:      
 
Domain Number 28 Region: 2287-2390
Classification Level Classification E-value
Superfamily Cadherin-like 0.000000131
Family Cadherin 0.0045
Further Details:      
 
Domain Number 29 Region: 3992-4032
Classification Level Classification E-value
Superfamily EGF/Laminin 0.000000518
Family EGF-type module 0.018
Further Details:      
 
Domain Number 30 Region: 4034-4075
Classification Level Classification E-value
Superfamily EGF/Laminin 0.000000792
Family EGF-type module 0.021
Further Details:      
 
Domain Number 31 Region: 1245-1319
Classification Level Classification E-value
Superfamily Cadherin-like 0.00005
Family Cadherin 0.0075
Further Details:      
 
Domain Number 32 Region: 3426-3529
Classification Level Classification E-value
Superfamily Cadherin-like 0.0000614
Family Cadherin 0.0067
Further Details:      
 
Weak hits

Sequence:  XP_001899725.1.25112
Domain Number - Region: 1336-1427
Classification Level Classification E-value
Superfamily Cadherin-like 0.00103
Family Cadherin 0.0081
Further Details:      
 
Domain Number - Region: 2921-3023
Classification Level Classification E-value
Superfamily Cadherin-like 0.00271
Family Cadherin 0.014
Further Details:      
 
Domain Number - Region: 31-142
Classification Level Classification E-value
Superfamily Cadherin-like 0.00424
Family Cadherin 0.0064
Further Details:      
 
Domain Number - Region: 1548-1603
Classification Level Classification E-value
Superfamily Cadherin-like 0.065
Family Cadherin 0.0097
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) XP_001899725.1.25112
Sequence length 4483
Comment Cadherin domain containing protein [Brugia malayi]; AA=GCF_000002995.3; RF=representative genome; TAX=6279; STAX=6279; NAME=Brugia malayi; AL=Scaffold; RT=Major
Sequence
MASRRLLLLAPLLFSLVGSSWNYRRKIDTFQFTAPVYNVSLEENARGKDIYAIVNEPIRM
GVPLPSDDAVLKFRIVEGDRQYFKAEVKTVGDFAFLLIRYRNDGILNRELKDRYEFLIKA
SCRRKDATNLETTVMVNLFVRDQNDAGPIFEKDEYRTEVKQNVSPFTTILQVQASDADVA
LNSQIYYSLVEWSLDFMVDPISGAIRNLRLLESGTYELIVLAEDRASRLFRKKAHSDNGN
NLFNHNKAKAVITVEPVERNKRKLSVEVKPISVSLWNVTQTVAIARIEGVAADVVTTLEI
VDGEYAGAFVLKKDSSSANVWLVETISGIWPQADWFIQLKATAVDDFVENLMENISVQLK
GKRLVQYDDNLEVMQIVVNESVPLGYVLTQLKAHVVNGIDGDNEQIRYSISNTDKPFSVD
ENNGYLRVIKWLDYENVSSYRFEVSAKLLDSTLEAKKAVEVIVADSNDHCPTFAVKWTRG
DPIALSRNYPINKVLFKAEALDIDSGANGRIRYELIGETVTIMRIFTVIPDSGEVVLQQK
PPDNESQWKLRIRASDAGWPFPRSSEVLISIYISGTNPPPKTKPSFLRKPQNDHSPVFMK
QTVFVVSADTPPGKVVGRIESHDDDMGYAGLIRFGTFDKFFALEPFTGEVVLLAPLGELL
RNKNKKKQMEYIVEIIACDWGQPVRCTNGTVTFLITEANVYRPXFEKPYYRVHIAEDTTI
GTKFLAVLAQDNDYGDNGQVGYQIIDSQNHFQIDENTGVLQVMTKLDREEVXFHRLTIMA
FDHGHPMKVTFVNVTVVLTDINDNAPLCVEPIRKIIIPEDYPNNALLTCVAAWDPDEGKN
GKVAYTFDTIIETSLTLPFRIQEDTGCIFVNTDEPFDFETINRYNLSVEAMDNGEPMLSS
ICTVLVEFSDVNENLFPPLFDDIAREATVYENVPLWTEVFALKAVDPDSPEMPVKYTVID
GDGISSFIIDSEGILRTSIVLDREACDSYWLTIEACDMNPVPLCSVLHVFVRVLDINDHI
PLSIHPIYFSTIPENSPEDTVITKVEAEDKDDLSDRHDITNIRFKIVSGDPQSFFAIDSK
TGYIVTRGKRRLDRETQKEHVIVVEICDQGHPKLCTTVSVVITITDLNDNLPLFKQTTYN
FNVPADKIGELCRVFAMDIDEGQNARILYNFTEADPRFSIDSDGQIITTDSLKENENYQL
XIKASDMGQPLQTSSPVLVTLNAVRRHTKKTVNGKPKLLNENRWSRLSISDADSIGETIG
LIEAEDPDGDQLWWKITDGNPNNTFAISCDAGELYLAKSLDLIKKNITIVKLKFTVDDGL
DTTEGVVLIEISRKYRPEFDAHYHKILVPKTAPIGTVVHTLKATIEKLNDSISDRGIIFG
IHVVEDIAVTDILLINPSSGEVVIAEPLNNIVTNFFIIVVYARFNQMINYAQLGISLFDE
TKTPPKFVVSEYFTTISTSLPVGTPVLTVRAYDSDHSSIQYSIIEGNEDGHFAINEYSGE
IRTSQLISYNHERTTLIVQASIQKNSSLTDRCSVRINILNDDLGRVNFPQPSYSLTVHES
TPPNTIVYILKTNSVMSIRYSFRDPCPFLSVHPISGVISIKLVTSAASVPHTCIAIARNS
LGTEDFMELKINVVSENQYAPYFSSTVYQGYIYENMPLNSSVLLEDGRQLLVKAIDHDRG
INGLVTYCIVSPLEPYFTIDYISGAILTKREIDFEKVGAFMNVFEELAKINVVDTRTIRQ
MTDVKHWSFYVQASDSAPQVLTSPVPALVEIMVFDMNDEPPSFIQEYYNATLFLPTLKNT
TVCYVTAIDVDTVGILRYAIIASDDSQLFAIEEFTGRIYTSGNSSADYAKSDYEINLVVS
DGLKSDSTVLLVRTENTSETGSTIKFLATNYEAVITENMTSSIMVQLLTVCAISTVNGSL
LYSILNPSSYFIVGVTSGIISWTGTAIDREKMPVVKLIVQARLSNGANERAQSIVTIKVE
DKNDCEPRFIGLPYELTIPRDIKLADKVTNVKAVDADEGFNGAVRYKLKTSTEYFDINEY
DGKIVISRSLEIANFDSVSLEVIAEDQGEPSLSSSAHVVIHIVDRNIPIFGNRYQEAHIL
ESAAPGSLVTNVHAASIVGGRIGYAIKSGNDENRFRIDFDTGMINVHKPLDREKCTFYNL
TVVAIDVTRQGVRAESYVVVNVDDISDTPPHFTQFFYSISVSESAAIGTQLLQIEAIDPD
INDNHISYGITGPNASVLSVDPRSGVISLMKSLDFETMRLFKFKLTASDSMQLTSETDLL
LHVTDANDVAPRFISKTFNSVVESETPINHFITKLDASDEDIMSNLGDGNRFLFSIIDGD
VTLLQINQSTGVVSLLRAVAEDDLNIGKKHFNVSVSDGIFTDFCLLIVKIVRSPSEHQLP
RFERMHYSAAVQENGPIGMTVMTVQAYNGIPPLRYSFNGCHENCSGILNIDETTGKVYTR
NLFDYEAQRIHQFVIMVTDAGDRCAFATLTLSVIDENDNIPQFISSKVEISVPVDSRPGE
SVLMVFAFDYDVDDELEYSIVDSDEIRSKYFTIHPKQGLISVKELLNDLVGEQISLFVRV
TDSADPPHQXETSVILNVSPIVHLPKFSTQHFLFSVSEDVPIGTVVGRLQQDSQLELSDV
FFSLVSMDNLSDFPFSVKQESGQIVVNSVLDYEKTREIRFLVSLHSQRQLNAKAVSLVTV
RITDVNDNKPRFEITSERVVISEDLPIGSSITIIRAVDEDAVGLNSKVQYFLEEGNNSST
FKLDQETGWLSLFKEVDREVIEEYALIVNARDGGGQSTRKKITVVLKDVNDSPPQFSQET
YFIEQYMEDLRVGQDILQLQVHDPDLYPNNVTSLYIMRGNEHGIFGLEMNSLVLHKLPTD
SDSLESHLLILAHDGKYTATAEVVVKLLSNFSQFQCEPREILRNITEDSPTGTIIKMGYQ
KVRKSLRFYLTGSESNLFAVENSGTVVVRDQLSSHISNQVELFLRAESPESLCIQRIIVK
IERTSKGRVTFTQPVFYGMVRENRNATKEEKVFATRLETTIDDLDGIGSVTFKFANNSNQ
YLDLFDIDSETGVIAAISSLDREIKDQYDFSVLAVSTAGNSAEAKVIIDVGDVNDNAPVF
EQNIYHLRIAEDEALGKELLQLKAYGGDDKEIISYQMQASDDVAKYLSIDANSGLLKLAS
VLDFEKLEKFMVSVIATDSGKPPLNSTCEIDVEILDVNDNPPLFMQHIYRAMVLENMQRG
TKVVQVLANDPDSEHFGRVSYSITNDAVGFTIEEDGWITTTEMLDREVKSTYRLIVKAVD
GGTPPLSDSTIVEIEVEDENDNAPVFKHCNMTAVVQESVEPGHVILPIFITDNDKEPNTG
PYRLEIIGDGASLFAFDRNLNLITTKRLPPHAKKEVYLLSVKVSDRDNLSTECPMTLFVK
EESRHAPQSNPLKITLNTLMGEFLGGIVGKIMATDEDSTDMLRYSLADREASANTIWSNH
QHSKIPFSIDSETGDIIGEADLLAGTYRFNVSVTDGKYIAVVPVVIDVISIDQDALDHSV
SVRIHNLLGETFFNKHVKNFMHSLSRFLNVKPQNVRILSVQSTLVRHHLLARQLNNKTTS
EQDLDILFTVSRADSRGYHRPNFIRQRLEDNVAQLSDDIGREIISIITEMCRRDVCANGE
CRDRLYLDDTHNVCYKTDRQSFSAPVHLRTYDCTCRTGYAGKRCDIPVDKCSRDQCTKEE
ICVPMNTDIGFDCICPPGTTGDRCDATVCGRDRRECSQGAEIGVGGDGFFQITVANSVER
RLELTIYFRTTSADAVIMYGAGNSDFHTIEVERRYVQYRWNCGTGPGVVRINQQTVSDGK
WHSLKVSRRSRHAKLVLDGLYEKEGDSPQGSDVVNLYRQDIRLTFGAMVTQSVDDSTFTT
ANDLKPIVTKGMIGCFGLMTKYGSIFRRISVDGYEVSKTKQSLYLYNTRLNCNAIVSAPC
AANPCKNEGTCIPSSEKAYECACPPRYSGSNCEIDLTSCVSRPCPRGVECINLHNDFYCS
CPHGFTGKTCQLRDWDPCLSNPCGHFGSCIRLPHSATFICNCSHGYSGTACKDRITDLIA
DGWPLNAIKIAGLIIVILLLIIFATLIICIYLRIKKSRKSPKVREMEYETNNYNPRVSMS
YEGVSHAGVTPAPPLFPRLHNSNYEKGLPTVQVRPLPIHERISSSSIGGASRSPSLAGSN
RCRIRWIAESGSIRNCGSERCIVSCDEIEPLASNETLRRYGEVIMGDDDEMASCSSSQLQ
LSVADRCRRSSGPRYKTGMKRTRYIRASNEAQTKEDWRKQCEKRINEACDAAAELRGERL
KSSAGINKNVTNDCSLNIKDDDDYMTMQPVHRRVIIQSSESQRRPLLETSDSDGMESADF
SYPDEVKPSQHRKPPPPPAHNIKRKNSKAIVSSSDVPNRVYDEPAIDVGDKKSSKIVKKT
QSTSELAHSLERFEDFGNIDDSDDDRTVNTSTSSNVHQTMAVL
Download sequence
Identical sequences XP_001899725.1.25112

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