The results are sorted from lowest E-value to highest E-value. Strong classifications have a low E-value. Weak classifications have an E-value greater than 0.0001. Weak hits are shown in gray. Weak hits are not shown on the domain architecture.
The family level classification is conditional on the domain being a member of the specified superfamily. There is a possibility that the selected domain is a member of a sub-family for which no structure has yet been solved.
| Sequence: |
TC008291 |
| Domain Number 1 |
Region: 543-722 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Fibronectin type III |
5.11e-33 |
| Family |
Fibronectin type III |
0.0014 |
| Further Details: |
|
| |
| Domain Number 2 |
Region: 156-254 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Immunoglobulin |
7.09e-23 |
| Family |
I set domains |
0.0074 |
| Further Details: |
|
| |
| Domain Number 3 |
Region: 259-356 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Immunoglobulin |
6.67e-20 |
| Family |
I set domains |
0.013 |
| Further Details: |
|
| |
| Domain Number 4 |
Region: 448-540 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Immunoglobulin |
2.41e-16 |
| Family |
I set domains |
0.0085 |
| Further Details: |
|
| |
| Domain Number 5 |
Region: 50-169 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Immunoglobulin |
7.89e-16 |
| Family |
V set domains (antibody variable domain-like) |
0.061 |
| Further Details: |
|
| |
| Domain Number 6 |
Region: 372-455 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Immunoglobulin |
0.000000000000945 |
| Family |
I set domains |
0.02 |
| Further Details: |
|
| |
| Sequence: |
TC008291 |
| Domain Number - |
Region: 1103-1167 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Formin homology 2 domain (FH2 domain) |
0.00549 |
| Family |
Formin homology 2 domain (FH2 domain) |
0.04 |
| Further Details: |
|
| |
The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by 
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Information Content (IC) is an information theoretic score measured in bits of how informative it is to assign a given ontological term to a domain archtecture. The higher the score the more informative it is to talk about the term given the domain architecture.
H-score (hypergeometric score) indicates the strength of assigning an ontological term to this domain architecture. Assignments with higher scores are of a better quality. Details for the methodology be found on the dcGO website.
| Molecular Function |
IC (bits) |
H-Score |
| Biological Process |
IC (bits) |
H-Score |
| Cellular Component |
IC (bits) |
H-Score |
