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Domain assignment for A0A0E3RY30 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  A0A0E3RY30
Domain Number 1 Region: 8-133,249-405
Classification Level Classification E-value
Superfamily Substrate-binding domain of HMG-CoA reductase 3.14e-89
Family Substrate-binding domain of HMG-CoA reductase 0.00000205
Further Details:      
 
Domain Number 2 Region: 137-251
Classification Level Classification E-value
Superfamily NAD-binding domain of HMG-CoA reductase 3.4e-42
Family NAD-binding domain of HMG-CoA reductase 0.00017
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score

Protein sequence

External link(s) A0A0E3RY30
Sequence length 418
Comment (tr|A0A0E3RY30|A0A0E3RY30_METMZ) 3-hydroxy-3-methylglutaryl coenzyme A reductase {ECO:0000256|RuleBase:RU361219} KW=Complete proteome OX=1434113 OS=Methanosarcina mazei C16. GN=MSMAC_0968 OC=Methanosarcinaceae; Methanosarcina.
Sequence
MFTEAYELTEEEKLLLQKVLDGDIAFRKIEEFADPLTAVKIRRLAIQEYGKLEFEHIQNF
SLDVESVTKRNIENMIGAVQIPLGVAGLLKVNGEYAAGEYYIPLATTEGALVASVNRGCS
VITRSGGANVRVFEDEMTRAPVFKLESLERARKFYDWVKSPETFEQMKQAAEKTTRFGKL
LSVKPFVTGTYIYLRFSYDTKDAMGMNMVTIATDAVMHLIEDEFGAHPVTLSGNMCTDKK
PASISAILGRGKTVVAEVTIPQEIVKETLKCTPESMFEVNYSKNLLGSARAGAMGFNAHA
ANIIAAVYLACGQDAAHVVEGSTAITSMELTKYEEIHCSVTLPALPVGTVGGGTGLGTQR
DCLNILGVAGAGDTPGINSRKFAEIVASAVLAGEISLIGAQAAGHLARAHAQLGRGKF
Download sequence
Identical sequences A0A0E3LS00 A0A0E3PUE2 A0A0E3RR28 A0A0E3RY30 A0A0F8IEH1 M1PUC9
WP_015411028.1.12270 WP_015411028.1.13133 WP_015411028.1.13782 WP_015411028.1.14209 WP_015411028.1.14583 WP_015411028.1.14776 WP_015411028.1.15587 WP_015411028.1.16483 WP_015411028.1.16878 WP_015411028.1.18729 WP_015411028.1.18783 WP_015411028.1.21267 WP_015411028.1.21501 WP_015411028.1.2157 WP_015411028.1.21918 WP_015411028.1.24179 WP_015411028.1.29103 WP_015411028.1.29761 WP_015411028.1.32345 WP_015411028.1.33522 WP_015411028.1.40449 WP_015411028.1.41322 WP_015411028.1.43564 WP_015411028.1.43834 WP_015411028.1.44090 WP_015411028.1.4739 WP_015411028.1.4970 WP_015411028.1.53089 WP_015411028.1.53770 WP_015411028.1.57580 WP_015411028.1.58691 WP_015411028.1.61041 WP_015411028.1.62876 WP_015411028.1.63409 WP_015411028.1.64722 WP_015411028.1.65224 WP_015411028.1.66913 WP_015411028.1.7135 WP_015411028.1.7314 WP_015411028.1.73216 WP_015411028.1.74065 WP_015411028.1.75484 WP_015411028.1.75785 WP_015411028.1.7642 WP_015411028.1.76508 WP_015411028.1.8229 WP_015411028.1.82623 WP_015411028.1.82674 WP_015411028.1.83034 WP_015411028.1.8430 WP_015411028.1.9066 WP_015411028.1.90871 WP_015411028.1.91617 WP_015411028.1.94933 WP_015411028.1.95514 gi|452208949|ref|YP_007489063.1|

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