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Domain assignment for A0A2K6MR51 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  A0A2K6MR51
Domain Number 1 Region: 375-565
Classification Level Classification E-value
Superfamily CAPPD, an extracellular domain of amyloid beta A4 protein 8.89e-83
Family CAPPD, an extracellular domain of amyloid beta A4 protein 0.0000000055
Further Details:      
 
Domain Number 2 Region: 29-123
Classification Level Classification E-value
Superfamily A heparin-binding domain 1.57e-44
Family A heparin-binding domain 0.00000102
Further Details:      
 
Domain Number 3 Region: 124-188
Classification Level Classification E-value
Superfamily Amyloid beta a4 protein copper binding domain (domain 2) 2.62e-29
Family Amyloid beta a4 protein copper binding domain (domain 2) 0.00001
Further Details:      
 
Domain Number 4 Region: 286-344
Classification Level Classification E-value
Superfamily BPTI-like 6.67e-21
Family Small Kunitz-type inhibitors & BPTI-like toxins 0.0000814
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score

Protein sequence

External link(s) A0A2K6MR51
Sequence length 752
Comment (tr|A0A2K6MR51|A0A2K6MR51_RHIBE) Amyloid beta precursor protein {ECO:0000313|Ensembl:ENSRBIP00000038212} KW=Complete proteome OX=61621 OS=Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti). GN=APP OC=Catarrhini; Cercopithecidae; Colobinae; Rhinopithecus.
Sequence
MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTK
TCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVG
EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR
GVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEE
EADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPC
RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVMSQSLRKTTREPLTQD
PVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQA
KNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITAL
QAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYER
MNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTET
KTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEFRHD
SGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEV
DAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Download sequence
Identical sequences A0A2I3MNJ9 A0A2K6MR51 A0A2K6QWN0
XP_010381739.1.97406 XP_017711956.1.44346

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