The results are sorted from lowest E-value to highest E-value. Strong classifications have a low E-value. Weak classifications have an E-value greater than 0.0001. Weak hits are shown in gray. Weak hits are not shown on the domain architecture.
The family level classification is conditional on the domain being a member of the specified superfamily. There is a possibility that the selected domain is a member of a sub-family for which no structure has yet been solved.
| Sequence: |
E2RI87 |
| Domain Number 1 |
Region: 29-227 |
| Classification Level |
Classification |
E-value |
| Superfamily |
p53-like transcription factors |
1.74e-75 |
| Family |
STAT DNA-binding domain |
0.000000479 |
| Further Details: |
|
| |
| Domain Number 2 |
Region: 780-991 |
| Classification Level |
Classification |
E-value |
| Superfamily |
p53-like transcription factors |
2.57e-75 |
| Family |
STAT DNA-binding domain |
0.00000000802 |
| Further Details: |
|
| |
| Domain Number 3 |
Region: 599-780 |
| Classification Level |
Classification |
E-value |
| Superfamily |
STAT |
9.81e-63 |
| Family |
STAT |
0.0000000158 |
| Further Details: |
|
| |
| Domain Number 4 |
Region: 466-586 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Transcription factor STAT-4 N-domain |
8.76e-44 |
| Family |
Transcription factor STAT-4 N-domain |
0.0000193 |
| Further Details: |
|
| |
| Domain Number 5 |
Region: 992-1133 |
| Classification Level |
Classification |
E-value |
| Superfamily |
SH2 domain |
1.06e-42 |
| Family |
SH2 domain |
0.000000141 |
| Further Details: |
|
| |
| Domain Number 6 |
Region: 228-348 |
| Classification Level |
Classification |
E-value |
| Superfamily |
SH2 domain |
6.46e-42 |
| Family |
SH2 domain |
0.00000457 |
| Further Details: |
|
| |
The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by 
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Information Content (IC) is an information theoretic score measured in bits of how informative it is to assign a given ontological term to a domain archtecture. The higher the score the more informative it is to talk about the term given the domain architecture.
H-score (hypergeometric score) indicates the strength of assigning an ontological term to this domain architecture. Assignments with higher scores are of a better quality. Details for the methodology be found on the dcGO website.
| Biological Process |
IC (bits) |
H-Score |
| Molecular Function |
IC (bits) |
H-Score |
| Cellular Component |
IC (bits) |
H-Score |
