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Domain assignment for P07196 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  P07196
Domain Number 1 Region: 318-395
Classification Level Classification E-value
Superfamily Intermediate filament protein, coiled coil region 1.74e-23
Family Intermediate filament protein, coiled coil region 0.0000878
Further Details:      
 
Domain Number 2 Region: 89-122
Classification Level Classification E-value
Superfamily Intermediate filament protein, coiled coil region 0.0000000000204
Family Intermediate filament protein, coiled coil region 0.0011
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score

Protein sequence

External link(s) P07196
Sequence length 543
Comment (sp|P07196|NFL_HUMAN) Neurofilament triplet L protein KW=Complete proteome; Reference proteome OX=9606 OS=Homo sapiens (Human). GN=NEFL; OC=Catarrhini; Hominidae; Homo.
Sequence
MSSFSYEPYYSTSYKRRYVETPRVHISSVRSGYSTARSAYSSYSAPVSSSLSVRRSYSSS
SGSLMPSLENLDLSQVAAISNDLKSIRTQEKAQLQDLNDRFASFIERVHELEQQNKVLEA
ELLVLRQKHSEPSRFRALYEQEIRDLRLAAEDATNEKQALQGEREGLEETLRNLQARYEE
EVLSREDAEGRLMEARKGADEAALARAELEKRIDSLMDEISFLKKVHEEEIAELQAQIQY
AQISVEMDVTKPDLSAALKDIRAQYEKLAAKNMQNAEEWFKSRFTVLTESAAKNTDAVRA
AKDEVSESRRLLKAKTLEIEACRGMNEALEKQLQELEDKQNADISAMQDTINKLENELRT
TKSEMARYLKEYQDLLNVKMALDIEIAAYRKLLEGEETRLSFTSVGSITSGYSQSSQVFG
RSAYGGLQTSSYLMSTRSFPSYYTSHVQEEQIEVEETIEAAKAEEAKDEPPSEGEAEEEE
KDKEEAEEEEAAEEEEAAKEESEEAKEEEEGGEGEEGEETKEAEEEEKKVEGAGEEQAAK
KKD
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Identical sequences A0A2I3SJH8 A0A2J8X4Z4 G3RNG2 P07196 Q5R408
ENSGGOP00000001414 ENSPPYP00000020675 NYSGRC-105990539 ENSPPYP00000020675 NP_006149.2.87134 NP_006149.2.92137 XP_003823612.1.60992 XP_004046845.1.27298 XP_519665.2.37143 gi|105990539|ref|NP_006149.2| ENSGGOP00000017329 9606.ENSP00000221169 ENSP00000482169

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