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Domain assignment for U6E8V8 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  U6E8V8
Domain Number 1 Region: 1-456
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 1.83e-134
Family Clostridium neurotoxins, catalytic domain 0.00000211
Further Details:      
 
Domain Number 2 Region: 459-783
Classification Level Classification E-value
Superfamily Clostridium neurotoxins, "coiled-coil" domain 2.09e-111
Family Clostridium neurotoxins, "coiled-coil" domain 0.000000176
Further Details:      
 
Domain Number 3 Region: 782-952
Classification Level Classification E-value
Superfamily Concanavalin A-like lectins/glucanases 7.92e-38
Family Clostridium neurotoxins, the second last domain 0.0000143
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) U6E8V8
Sequence length 958
Comment (tr|U6E8V8|U6E8V8_CLOBO) Botulinum neurotoxin type C/D {ECO:0000313|EMBL:CDF47113.1} OX=1491 OS=Clostridium botulinum. GN=botC OC=Clostridium.
Sequence
LKEIIKLFKRINSREIGEELIYRLATDIPFPGNNNTPINTFDFDVDFNSVDVKTRQGNNW
VKTGSINPSVIITGPRENIIDPETSTFKLTNNTFAAQEGFGALSIISISPRFMLTYSNAT
NNVGEGRFSKSEFCMDPILILMHELNHAMHNLYGIAIPNDQRISSVTSNIFYSQYKVKLE
YAEIYAFGGPTIDLIPKSARKYFEEKALDYYRSIAKRLNSITTANPSSFNKYIGEYKQKL
IRKYRFVVESSGEVAVDRNKFAELYKELTQIFTEFNYAKIYNVQNRKIYLSNVYTPVTAN
ILDDNVYDIQNGFNIPKSNLNVLFMGQNLSRNPALRKVNPENMLYLFTKFCHKAIDGRSL
YNKTLDCRELLVKNTDLPFIGDISDIKTDIFLSKDINEETEVIDYPDNVSVDQVILSKNT
SEHGQLDLLYPIIEGESQVLPGENQVFYDNRTQNVDYLNSYYYLESQKLSDNVEDFTFTT
SIEEALDNSGKVYTYFPKLADKVNTGVQGGLFLMWANDVVEDFTTNILRKDTLDKISDVS
AIIPYIGPALNISNSVRRGNFTEAFAVTGVTILLEAFQEFTIPALGAFVIYSKVQERNEI
IKTIDNCLEQRIKRWKDSYEWMIGTWLSRITTQFNNISYQMYDSLNYQADAIKDKIDLEY
KKYSGSDKENIKSQVENLKNSLDIKISEAMNNINKFIRECSVTYLFKNMLPKVIDELNKF
DLKTKTELINLIDSHNIILVGEVDRLKAKVNESFENTIPFNIFSYTNNSLLKDIINEYFN
SINDSKILSLQNKKNALVDTSGYNAEVRLEGDVQVNTIYTNDFKLSSSGDKIIVNLNNNI
LYSAIYENSSVSFWIKISKDLTNSHNEYTIINSIKQNSGWKLCIRNGNIEWILQDINRKY
KSLIFDYSESLSHTGYTNKWFFVTITNNIMGYMKLYINGELKQSERIEDLNEVKLDKT
Download sequence
Identical sequences U6E8V8

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