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Domain assignment for A0A0A0MS70 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  A0A0A0MS70
Domain Number 1 Region: 173-307
Classification Level Classification E-value
Superfamily Toll/Interleukin receptor TIR domain 1.7e-28
Family Toll/Interleukin receptor TIR domain 0.0011
Further Details:      
 
Domain Number 2 Region: 20-135
Classification Level Classification E-value
Superfamily DEATH domain 3.24e-26
Family DEATH domain, DD 0.0034
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score

Protein sequence

External link(s) A0A0A0MS70
Sequence length 309
Comment (tr|A0A0A0MS70|A0A0A0MS70_HUMAN) Myeloid differentiation primary response protein MyD88 {ECO:0000256|PIRNR:PIRNR037756} KW=Complete proteome; Reference proteome OX=9606 OS=Homo sapiens (Human). GN=MYD88 OC=Catarrhini; Hominidae; Homo.
Sequence
MRPDRAEAPGPPAMAAGGPGAGSAAPVSSTSSLPLAALNMRVRRRLSLFLNVRTQVAADW
TALAEEMDFEYLEIRQLETQADPTGRLLDAWQGRPGASVGRLLELLTKLGRDDVLLELGP
SIEEDCQKYILKQQQEEAEKPLQVAAVDSSVPRTAELAGITTLDDPLGHMPERFDAFICY
CPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEKRCRRMVVVVSDDY
LQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPSILRFITVCDYTNPCTKSWFWT
RLAKALSLP
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Identical sequences A0A0A0MS70
NP_002459.2.87134 NP_002459.2.92137 ENSP00000379625 gi|197276654|ref|NP_002459.2| 9606.ENSP00000379625 ENSP00000379625

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