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Domain assignment for A0A2K5WW63 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  A0A2K5WW63
Domain Number 1 Region: 1123-1298
Classification Level Classification E-value
Superfamily GTPase activation domain, GAP 1.04e-40
Family BCR-homology GTPase activation domain (BH-domain) 0.00059
Further Details:      
 
Domain Number 2 Region: 685-800
Classification Level Classification E-value
Superfamily ArfGap/RecO-like zinc finger 9.94e-36
Family Pyk2-associated protein beta ARF-GAP domain 0.0015
Further Details:      
 
Domain Number 3 Region: 877-1038
Classification Level Classification E-value
Superfamily PH domain-like 3.67e-24
Family Pleckstrin-homology domain (PH domain) 0.016
Further Details:      
 
Domain Number 4 Region: 450-572
Classification Level Classification E-value
Superfamily PH domain-like 4.11e-24
Family Pleckstrin-homology domain (PH domain) 0.0000113
Further Details:      
 
Domain Number 5 Region: 1410-1547
Classification Level Classification E-value
Superfamily PH domain-like 1.92e-19
Family Pleckstrin-homology domain (PH domain) 0.018
Further Details:      
 
Domain Number 6 Region: 5-75
Classification Level Classification E-value
Superfamily SAM/Pointed domain 2.51e-17
Family SAM (sterile alpha motif) domain 0.0000313
Further Details:      
 
Domain Number 7 Region: 586-684
Classification Level Classification E-value
Superfamily PH domain-like 0.00000000000000308
Family Pleckstrin-homology domain (PH domain) 0.016
Further Details:      
 
Domain Number 8 Region: 1015-1109
Classification Level Classification E-value
Superfamily PH domain-like 0.000000222
Family Pleckstrin-homology domain (PH domain) 0.013
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score

Protein sequence

External link(s) A0A2K5WW63
Sequence length 1680
Comment (tr|A0A2K5WW63|A0A2K5WW63_MACFA) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 {ECO:0000313|Ensembl:ENSMFAP00000041461} OX=9541 OS=Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey). GN=ARAP2 OC=Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Sequence
MSSVSEVNVDIKDFLMSINLEQYLLHFHESGFTTVKDCAVINDSLLQKIGISPTGHRRRI
LKQLQIILSKMQDFPIYANVHKTKKNDDPSKDHNVPSSDQNICIELSSSSSVQMPSPPQL
ETVTKKLEDDASVERSQYPQSDNKLSPPKRDFPTAEEPHLNLGSLNNSLFGSENIKIESL
ITKKTMDHTIEEQQTEKVKLISENLNKLPNADSECLSSVGCSTSETNSRNGTNGLLDGSP
PSPFFKFQGEMIVNDLYVPSSPILAPMRSRSKLVSRPSRSFLLRHRPVPEIPGSTKGISG
SYFRERRNVATSTEKSVAWQNSNEENSSSIFPYGETFLFQRLENSKKRSIKNEFLTQEEA
LKGEATTATNSFIIKSSIYDNRKEKISEDKVEDIWIPREDKNNFLIDTASESEYSTVEEC
FQSLRRKNSKASKSRTQKALTLDSVNRHSYPLSSTSGNADSSAVSSQAISPYACFYGASV
KKVKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEKEMYSKGIIPLSAISTVRVQGDN
KFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQSQGIVTPEKCGYLELRGYKA
KIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFTA
ETEKEKQDWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVICK
KCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELHMDS
PVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMCA
TGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDIHSEGVLSQESSQSTFLCDFLYQ
APAAASKLSSEKKLLEETNKKWCVLEGGFLSYYESDKSTTPNGTININEVICLAIHKEDF
YLNTGPIFIFEIYLPSERVFLFGAETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQL
FYKDCHALDQWRKGWFAMDKSSLHFCLQMQEVQGDRMHLRRLQELTISTMVQNGEKLDVL
LLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVTQ
YGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTGVLKSFLSDIDDALL
TKELYPYWISALDAQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMNA
HNLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVSQAGDLLIEVYVERKEPDCSII
IRISPVMEAEELTNDILAIKNIIPTKGDIWATFEVIENEELERPLHYKENVLEQVLRWSS
LAEPGSAYLVVKKFLTADTIKHCSDRSTLGSIKEGILKIKEEPSKILSGNKFQDRYFVLR
DGFLFLYKDVKSSKHDKMFSLSSVKFYRGVKKKMKPPTSWGLTAYSEKHHWHLCCDSSRA
QMEWMTSIFVAQHENDIWPPAGKERKRSITKNPKIGGLPLIPIQHEGNATLARKNIESAR
AELERLRLVEKCDRESVDSSLKERASMVAHCLEHKDDKLRNRTRKHRSFNCLEDTEPEAP
LGQPKGHKGLKTLRKTEDRNSKATLDSDHKLPSRVIEELNVVLQRSRTLPRELQDEQILK
Download sequence
Identical sequences A0A2K5WW63
XP_015305720.1.63531

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