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Domain assignment for E2R0N1 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  E2R0N1
Domain Number 1 Region: 1180-1341
Classification Level Classification E-value
Superfamily PH domain-like 6.58e-75
Family Pleckstrin-homology domain (PH domain) 0.0000000425
Further Details:      
 
Domain Number 2 Region: 976-1183
Classification Level Classification E-value
Superfamily DBL homology domain (DH-domain) 1.05e-52
Family DBL homology domain (DH-domain) 0.00000000709
Further Details:      
 
Domain Number 3 Region: 459-581
Classification Level Classification E-value
Superfamily PH domain-like 5.9e-18
Family Pleckstrin-homology domain (PH domain) 0.021
Further Details:      
 
Domain Number 4 Region: 784-856
Classification Level Classification E-value
Superfamily PDZ domain-like 0.00000000319
Family PDZ domain 0.028
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) E2R0N1
Sequence length 1531
Comment (tr|E2R0N1|E2R0N1_CANLF) T-cell lymphoma invasion and metastasis 1 {ECO:0000313|Ensembl:ENSCAFP00000013005} KW=Complete proteome; Reference proteome OX=9615 OS=Canis lupus familiaris (Dog) (Canis familiaris). GN=TIAM1 OC=Canis.
Sequence
MGNAESQNVEHEFYGEKHASLGRKHTSRSLRLSHKARRTRHASSGKMIHRNSEVSTRSSS
TPSIPQSLAENGLEPFSQEGTLEDFGSPIWVDRVDMGLRPVSYTDSSVTPSVDSSIVLTA
ASVQSMPDSEESRLYGDDATYLADGGRRQHPYTSNGPTFMETASFKKKRSKSADIWREDS
LEFSLSDLSQEHLTSNEEILGSTEEKDCEEARGMEPRVSPRQLSTCQRANSLGDLYAQKN
SGVTANGGPRSKFAGCCRNLVSDIPDLANHKMPPAAAEESLPYSNYNTLPCRKSHCLSEG
ATNPQISHSNSMQGRRAKTTQDVNAGEGSEFADSGIEGATTDTDLLSRRSNATNSSYSPP
TGRAFVGSDSGSSSTGDAARQGVYENFRRELELSTTNSESLEEAGSAHSDEQSSGTLSSP
GQSDILLTAAQGTVRKAGALAVKNFLVHKKNKKVESATRRKWKHYWVFFSGCTLFFYESD
GRSGIDHNSIPKHAVWVENSIVQSVPEHPKKDFVFCLSNSLGDAFLFQTTSQTELENWIT
AIHSACAAAVARHHHKEDTLRLLKSEIKKLEQKIDMDEKMKKMGEMQLSSVTDSKKKKTI
LDQIFVWEQNLEQFQMDLFRYRCYLASLQGGELPNPKRLLAFASRPTKVAMGRLGIFSVS
SFHALVAARTGETGVRRRTQAMSRSASKRRSRFSSLWGLDTTSKKKQGRPSINQREKEMV
LPSVHQHNPDCDIWVHEYFTPSWFCLPNNQPALTVVRPGDTARDTLELICKLYKEIEICP
KVTQNIQIEKSDTASDNYGFSLSSVEEDGVRRLYVNSVKETGLASKKGLKAGDEILEINN
RAAGTLNSSVLKDFLSQPSLGLLVRTYPEPEGGLELLDCPPHRADGPVDLSESPLAFLSS
NPGHSLCSEQGSSAETAPEETEGPDLESSDETDHSSKSTEQVAAFCRSLHEMNPSDPSPP
PQDATGPQLATMRQLTDADKLRKVICELLETERTYVKDLNCLMERYLKPLQKETFLTQDE
LDVLFGNLTEMVEFQVEFLKTLEDGVRLVPDLEKLEKVDQFKKVLFSLGGSFLYYADRFK
LYSAFCASHTKVPKVLVKAKTDPAFKAFLDAQNPKQQHSATLESYLIKPIQRILKYPLLL
KELFALTDAESEEHYHLDVAIKTMNKVASHINEMQKIHEEFGAVFDQLIAEQTGEKKEVA
DLSMGDLLLHTTVIWPNPPASLGKWKKEPELAAFVFKTAVVLVYKDGSKQKKKLVGSHRL
SIYEDWDPFRFRHMIPTEALQVRALASADAEANAVCEIVHVKSESEGRPERVFHLCCSSP
ESRKDFLKAVHSILRDKHRRQLLKTESLPSSQQYVPFGGKRLCALKGARPAMSRAVSAPS
KSLGRRRRRLARNRFTIDSDAISASSPEKESQQPPGGGDTDRWVEEQFDLAQYEEQDDIK
ETDILSDEDEFCESVRGTAVDTELQEQLQAVSIGQRERGRRALDSHASRMTQLKKQAALS
GINGGLESPGDEVIWVRREDFAPSRKLNTEI
Download sequence
Identical sequences E2R0N1
ENSCAFP00000013005

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