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Domain assignment for E2RPK4 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  E2RPK4
Domain Number 1 Region: 160-367
Classification Level Classification E-value
Superfamily DBL homology domain (DH-domain) 3.4e-57
Family DBL homology domain (DH-domain) 0.00019
Further Details:      
 
Domain Number 2 Region: 350-496
Classification Level Classification E-value
Superfamily PH domain-like 1.62e-32
Family Pleckstrin-homology domain (PH domain) 0.002
Further Details:      
 
Domain Number 3 Region: 461-502,540-596
Classification Level Classification E-value
Superfamily FYVE/PHD zinc finger 5.28e-20
Family FYVE, a phosphatidylinositol-3-phosphate binding domain 0.0059
Further Details:      
 
Domain Number 4 Region: 628-726
Classification Level Classification E-value
Superfamily PH domain-like 1.71e-16
Family Pleckstrin-homology domain (PH domain) 0.0001
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) E2RPK4
Sequence length 746
Comment (tr|E2RPK4|E2RPK4_CANLF) FYVE, RhoGEF and PH domain containing 3 {ECO:0000313|Ensembl:ENSCAFP00000003318} KW=Complete proteome; Reference proteome OX=9615 OS=Canis lupus familiaris (Dog) (Canis familiaris). GN=FGD3 OC=Canis.
Sequence
MESEGTSSTTHAPGAVLGEPDAGPGCASLELPRADPGKLQGLPLGPRAHGKDPDLGSPGT
PTTSGDGPLDLGPSGGPNGGAKLPNRDSGIDSPSCSVVSEQFPCEEGGEASRGPAVLGHL
EAAPEGEAVREAADSNVGEGNGEEPDPKSSPLRAPVDPVKCPKSQKLLHIAQELLHTEET
YVKRLHLLDQVFCAQLVEAGIPSEVTTGIFSNISSIYRFHGHFLLPELQTRITQEWDTNP
RLGDILQKLAPFLKMYGEYVKNFDRAVELVSTWTQRSPLFKDIVQSIQKQDVCGNLTLQH
HMLEPVQRVPRYELLLKDYLKRLPRDAPDWKDAERSLELISTAANHSNAAIRKMEKMHKL
LEVYERLGGEEDIVNPANELIKEGPIQKLSAKSGSAQDRHLFLFNSMILYCVPKLRLMGQ
KFSVREKMDISGLQVQDIVKSNAAHTFIIKGRKRSLELQTRTEEEKKEWIQVIEDTIERH
KQNSQTFKAFSSSFGQDEDPSLPPNPSVVSASPEEPALAASGGGGVAGLESRRGSAKTGR
DKEKLGCRSCGEAFNSITKRKHRCKLCGVVICGKCSEFKAENGRQSRVCRGCFLTQRAVP
ESPSPEVAPEEPKHSTEGPAAVDPQPSLLCGHLQVSDSGAAWSEVWATIPASDPLELVLH
LQEDSQDGWPPRTVPLSGCTVSVLDPAEMPDSRHVWRLQRGQQSLYLSTPSVDLQKRWLE
ALSAAARGDPGLAALSAPSPSSVAWP
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Identical sequences E2RPK4
ENSCAFP00000003318 9615.ENSCAFP00000003318 ENSCAFP00000003318

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