The results are sorted from lowest E-value to highest E-value. Strong classifications have a low E-value. Weak classifications have an E-value greater than 0.0001. Weak hits are shown in gray. Weak hits are not shown on the domain architecture.
The family level classification is conditional on the domain being a member of the specified superfamily. There is a possibility that the selected domain is a member of a sub-family for which no structure has yet been solved.
| Sequence: |
E3E6S5 |
| Domain Number 1 |
Region: 598-777 |
| Classification Level |
Classification |
E-value |
| Superfamily |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase |
2.36e-42 |
| Family |
Histidine kinase |
0.0012 |
| Further Details: |
|
| |
| Domain Number 2 |
Region: 1116-1236 |
| Classification Level |
Classification |
E-value |
| Superfamily |
CheY-like |
7.4e-39 |
| Family |
CheY-related |
0.0064 |
| Further Details: |
|
| |
| Domain Number 3 |
Region: 966-1095 |
| Classification Level |
Classification |
E-value |
| Superfamily |
CheY-like |
3.27e-22 |
| Family |
CheY-related |
0.0063 |
| Further Details: |
|
| |
| Domain Number 4 |
Region: 846-961 |
| Classification Level |
Classification |
E-value |
| Superfamily |
CheY-like |
6.97e-22 |
| Family |
CheY-related |
0.00095 |
| Further Details: |
|
| |
| Domain Number 5 |
Region: 266-430 |
| Classification Level |
Classification |
E-value |
| Superfamily |
GAF domain-like |
3.19e-19 |
| Family |
GAF domain |
0.0081 |
| Further Details: |
|
| |
| Domain Number 6 |
Region: 528-611 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Homodimeric domain of signal transducing histidine kinase |
9.22e-19 |
| Family |
Homodimeric domain of signal transducing histidine kinase |
0.0024 |
| Further Details: |
|
| |
| Sequence: |
E3E6S5 |
| Domain Number - |
Region: 427-531 |
| Classification Level |
Classification |
E-value |
| Superfamily |
P-loop containing nucleoside triphosphate hydrolases |
0.000409 |
| Family |
G proteins |
0.07 |
| Further Details: |
|
| |
The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by 
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Information Content (IC) is an information theoretic score measured in bits of how informative it is to assign a given ontological term to a domain archtecture. The higher the score the more informative it is to talk about the term given the domain architecture.
H-score (hypergeometric score) indicates the strength of assigning an ontological term to this domain architecture. Assignments with higher scores are of a better quality. Details for the methodology be found on the dcGO website.
| Biological Process |
IC (bits) |
H-Score |
| Cellular Component |
IC (bits) |
H-Score |
| Molecular Function |
IC (bits) |
H-Score |
