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Domain assignment for E9QP44 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  E9QP44
Domain Number 1 Region: 1123-1298
Classification Level Classification E-value
Superfamily GTPase activation domain, GAP 1.86e-41
Family BCR-homology GTPase activation domain (BH-domain) 0.00058
Further Details:      
 
Domain Number 2 Region: 684-799
Classification Level Classification E-value
Superfamily ArfGap/RecO-like zinc finger 9.68e-36
Family Pyk2-associated protein beta ARF-GAP domain 0.0015
Further Details:      
 
Domain Number 3 Region: 445-571
Classification Level Classification E-value
Superfamily PH domain-like 2.33e-23
Family Pleckstrin-homology domain (PH domain) 0.0000166
Further Details:      
 
Domain Number 4 Region: 917-1037
Classification Level Classification E-value
Superfamily PH domain-like 1.84e-20
Family Pleckstrin-homology domain (PH domain) 0.015
Further Details:      
 
Domain Number 5 Region: 1421-1564
Classification Level Classification E-value
Superfamily PH domain-like 2.83e-20
Family Phosphotyrosine-binding domain (PTB) 0.082
Further Details:      
 
Domain Number 6 Region: 4-75
Classification Level Classification E-value
Superfamily SAM/Pointed domain 2.75e-17
Family SAM (sterile alpha motif) domain 0.0000631
Further Details:      
 
Domain Number 7 Region: 584-683
Classification Level Classification E-value
Superfamily PH domain-like 8.05e-16
Family Pleckstrin-homology domain (PH domain) 0.034
Further Details:      
 
Domain Number 8 Region: 1014-1114
Classification Level Classification E-value
Superfamily PH domain-like 0.0000000295
Family Pleckstrin-homology domain (PH domain) 0.016
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) E9QP44
Sequence length 1703
Comment (tr|E9QP44|E9QP44_MOUSE) Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 {ECO:0000313|Ensembl:ENSMUSP00000075924} KW=Complete proteome; Reference proteome OX=10090 OS=Mus musculus (Mouse). GN=Arap2 OC=Muroidea; Muridae; Murinae; Mus; Mus.
Sequence
MSSVSEVNADIRDFLMSINLEQYLLHFREFGFYTVRDCTSINDSVLHQIGISPTGHRRRI
LKQLQMIFSKMQDFPIYANVHKAKNGSTTKEQQHSDPSSSTHTGIECSDSITVHRPGPAP
SEMVTTSTLSEGNCQSPKSHDKLCLSSHDLLCPEEELHQNVDSSKDSLFGGVNVKIDPLI
TKRAVEYTAGEEHTEKGNLTSEDSSKALSTNTECLPSGDCPTSGTHSGNGTNGVLESFPP
TPFFQFQGEMVVNELYVPSSPVHGPMRSRSKLVSRPSRSFLLRHRPVPEIPGSTKSIPGS
YFRDRRSNTTSAGKSLTLKNSNEDNSTSIFPYGETFLFQRLESSKKRSIKNEFWPHENTV
KEEAATTRNSILTQSSIYDNRKEKVSEDKVEDIWIPREDKNNLAQDSASESEYSTVEECF
QSLRRKNSKASKSRTQKAFYLDPFNRHSYPLSSTSGNTEPSSTISNAISPYACFYGSSAA
KEKCGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNDREMYSKGIIPLTAISTVRAQGDNK
FEIVTTQRTFVFRVEKEEERNDWISILLSALKSPSLASQLQAAVAPEKCGYLELRGYKAK
IFTVLRGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRAVKQSFEIITPYRSFSFTAD
SEREKQEWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVICKK
CAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELQVDSP
VEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMCAT
GDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQYDAHFEGGSSQDAAQSSFLCDFLYQT
AAAASRVSSEKKLLEDTNKKWCVLEGGFLSYYENDRCTTPNGTINISEVICLAVHKEDFY
LNTGPIFVFEIYLPSERVFLFGAETSQIQRKWTETIAKRFVPFVAENLTEADYDLIGQLF
YKDCHALDQWRKGWFAMDKSSLCFCLQTQEAQEERMNLRRLQELTISTMVQNGEKVDVLL
LVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLCKNDVPIIVNSCIAFVTQY
GLGCKYIYQKDGDPLHISELLESFKKDARSVKLRAGKHQLEDVTGVLKSFLSDIDDALLT
KELYPYWVSALDTQDEKERTSKYRAFIRSLPGVNRATLAALIEHLYRVQKCSEINHMNAH
NLAMVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDTQV
SQAGDLLIEVFVERKEPDCSIIIRISPVMEAEELTNDILAIKNIIPMKGDIWATFEVIEN
EELERPLHYTENVLEQVLQWSSLAEPGSAYLVVKRFLTIDSIKQCREKSIKEGILKLKEE
PSKILSGNKFQDRCVVLRDGHLFIYKDPKSSKHDKMFPLRAMKFYLGVKKKMKPPTSWGL
TVYSEKHHWHLCCDSLQAQMEWMASIFIAQHENDIWPPAGKERKRSITKNPKIGGLPLIP
IQHERNATQARKNIETARAELERLRLSEKHDPRDFTDSSLKDRASLIAHCLEHKDEKLRN
RARKHRSFNCLEDTEAEGPHGLPKAYKGPKTLKKTEERNSKATLDADPKLPSKVIEELSV
VLQRSRPLHKELPDEQTLQKEVK
Download sequence
Identical sequences E9QP44
NP_848494.2.92730 XP_011239014.1.92730 ENSMUSP00000075924 ENSMUSP00000075924 ENSMUSP00000075924 10090.ENSMUSP00000075924

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