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Domain assignment for F1PET2 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  F1PET2
Domain Number 1 Region: 370-558
Classification Level Classification E-value
Superfamily Regulator of G-protein signaling, RGS 2.35e-66
Family Regulator of G-protein signaling, RGS 0.00000793
Further Details:      
 
Domain Number 2 Region: 767-996
Classification Level Classification E-value
Superfamily DBL homology domain (DH-domain) 6.54e-64
Family DBL homology domain (DH-domain) 0.0000000008
Further Details:      
 
Domain Number 3 Region: 1000-1130
Classification Level Classification E-value
Superfamily PH domain-like 7.87e-39
Family Pleckstrin-homology domain (PH domain) 0.00000125
Further Details:      
 
Domain Number 4 Region: 69-149
Classification Level Classification E-value
Superfamily PDZ domain-like 7.49e-22
Family PDZ domain 0.01
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) F1PET2
Sequence length 1543
Comment (tr|F1PET2|F1PET2_CANLF) Rho guanine nucleotide exchange factor 12 {ECO:0000313|Ensembl:ENSCAFP00000017590} KW=Complete proteome; Reference proteome OX=9615 OS=Canis lupus familiaris (Dog) (Canis familiaris). GN=ARHGEF12 OC=Canis.
Sequence
MSGTQPTITDRFPLKKPIRHGSILNRESPTDKKQKVERSASHDFDPTDSSSKKTKSSSEE
SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT
LVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPG
ASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQ
EAKKHIPQLQEQLSKATGSAQDGAVVTSSKPVGEPLTASEVEADPGEGIGRLDYCTGDAS
RPGSDSADSPKSALKERICLEENPEKSEVIQDTDTQSLFGSPSPRIAAHIIGAEDDDFGT
EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKQTNSKETRR
VFLEFHQFFLDRSAHLKVSVPDEISVDLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHL
EDFRQKRSMGLTLAESELTKLDAERDKDRVTLEKERACAEQIVAKIEEVLMTAQPVEEDK
SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDREGEEKGKRRGFPSI
LGPPRRPSRHDNSAIGRAMELQKQRHPKHLSTPSSVSPEPQDPAKLRQSALAGEGTEVGY
LPANPMSSVAAGATLSQEGGKENDTGSKQVGETPASGDCIDNTPRTPNTIFDFPPPPLDQ
VQEEEWEVERVTEHGTPKPFRKFDSIAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG
LKPSEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ
LHIGLNEQMKAVRKRNETSVIDQIGEDLLTWFSGPGEDKLKHAAATFCSNQPFALEMIKS
RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPMEREKV
KKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSNLKLSEYPNVEELRNLDLTKRKM
IHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI
KLNTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSAK
PIPLPQSPPCEGDNDEEAAPKLKVEHHSISVPGLQSPDRDLGLESPLISSKPQSHSLGTS
GKSEVDDLFVAERQFAKEQHTDGTLQEAGGSYQITIPDPHLPASEERWALDALRNLGLLK
QLLVQQLGLTEKSAQEDWPHFPRYRTASSGVQTDSGTQNSENSKAYPPGEGQMPFRTGTG
DISTCYSPRTSTESSAPRDSVVLAFQESQASNILVMDHMIMTPEMPPAEPEGSLDESGEH
FFDAREAHSDDNPSEGDGAVKKEEDVNLRISGNYLILDGYEAVQESSTDEEVASSLPPPP
TAGIPAMDCARPQQHSPQHAHSDGAASPFTPEFLVQQRWGAMEDSCFEIQSPPSCADSQS
QIMEYIRKIEADLEHLKKVEESYSILCQRLAGSALTDKHSDKS
Download sequence
Identical sequences F1PET2
ENSCAFP00000017590 ENSCAFP00000017590 XP_005619719.1.84170

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