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Domain assignment for F1PUV5 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  F1PUV5
Domain Number 1 Region: 25-225
Classification Level Classification E-value
Superfamily DBL homology domain (DH-domain) 2.88e-45
Family DBL homology domain (DH-domain) 0.00033
Further Details:      
 
Domain Number 2 Region: 256-450
Classification Level Classification E-value
Superfamily BAR/IMD domain-like 3.66e-37
Family BAR domain 0.012
Further Details:      
 
Domain Number 3 Region: 591-672
Classification Level Classification E-value
Superfamily SH3-domain 9.45e-21
Family SH3-domain 0.00063
Further Details:      
 
Domain Number 4 Region: 495-569
Classification Level Classification E-value
Superfamily SH3-domain 0.000000000000748
Family SH3-domain 0.0006
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) F1PUV5
Sequence length 675
Comment (tr|F1PUV5|F1PUV5_CANLF) Rho guanine nucleotide exchange factor 37 {ECO:0000313|Ensembl:ENSCAFP00000027005} KW=Complete proteome; Reference proteome OX=9615 OS=Canis lupus familiaris (Dog) (Canis familiaris). GN=ARHGEF37 OC=Canis.
Sequence
MAEHGTDEPSSRTGSPDGECQVLEDRSLLHQRLAVRELIDTEVSYLHMLQLCASDIRSRL
QQLPQGDLDVLFSNIDDVIEVNNRFLHDLQETESREEEQVHLIGNLFLKFQEELERVYKV
YCASYDQALLLVEAYRKEPELQREIQGIIETVVPQAGPSGLSFLLVIPLQRITKYPLLLQ
KILENTVPDASAYPVLQRAASALQDVNTNINEYKRRKEVASKYTKVEQLTLRERLARLNT
HTLSKKTTRLSQLLKQEAGLVPKTEDKEFDDLEERFHWVSLCVTEMKNNMAVYLDNLEAF
LRFRPQEYDLDIPGGPVVQYCSLMRELQLQAFPQFKQRLEGLVWQPLCSLAKALAGPQNL
IKKRLDKLLDFERVEEKLLEAGSVTYEEQEARHTYQALNSLLVAELPQLNQLAMHWLGQI
LCTFVGLQRDLAKHVLQRAEGSLAQLPHSHLSEPAFRKLVEDTLGQTGHQLRSFRENLDK
VLPPPATQPLLPGAERQVQALLSRYGPEKLYQVTSNISGAGTLDLTLPRGQIVALLQNKD
TKGNSSRWLVDTGGHRGYVPAGKLELYRVTPSQEEVRGQEWPHKDSRHLTPEPTPAPVSS
VPVVTQVVAVYPFVARSSHEVSLQAGQLVTVLEAQDKKGNPEWSLVEVNGQRGYVPSSFL
ARAPSPAPWGWSLPS
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Identical sequences F1PUV5
ENSCAFP00000027005 XP_005619364.1.84170 XP_005619365.1.84170 XP_546309.3.84170 ENSCAFP00000027005

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