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Domain assignment for F6TG39 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  F6TG39
Domain Number 1 Region: 48-266
Classification Level Classification E-value
Superfamily DBL homology domain (DH-domain) 2.36e-61
Family DBL homology domain (DH-domain) 0.0000156
Further Details:      
 
Domain Number 2 Region: 252-398
Classification Level Classification E-value
Superfamily PH domain-like 4.02e-34
Family Pleckstrin-homology domain (PH domain) 0.0006
Further Details:      
 
Domain Number 3 Region: 513-643
Classification Level Classification E-value
Superfamily "Winged helix" DNA-binding domain 2.78e-31
Family DEP domain 0.0012
Further Details:      
 
Domain Number 4 Region: 415-529
Classification Level Classification E-value
Superfamily "Winged helix" DNA-binding domain 5.39e-28
Family DEP domain 0.0031
Further Details:      
 
Domain Number 5 Region: 623-711
Classification Level Classification E-value
Superfamily PDZ domain-like 0.00000000125
Family PDZ domain 0.035
Further Details:      
 
Domain Number 6 Region: 714-776
Classification Level Classification E-value
Superfamily PDZ domain-like 0.00000000759
Family PDZ domain 0.023
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) F6TG39
Sequence length 1655
Comment (tr|F6TG39|F6TG39_MONDO) Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 {ECO:0000313|Ensembl:ENSMODP00000029097} KW=Complete proteome; Reference proteome OX=13616 OS=Monodelphis domestica (Gray short-tailed opossum). GN=PREX1 OC=Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis.
Sequence
MEPPAGGSSAGPPESLILGPAATPGPGPGPITASAGPAAAAAAAARDSERQLRLRLCVLN
EILGTERDYVGTLRFLQSAFLHRIRQNVADSADKCITEENVKILFSNIEDILEVHKEFLN
ALEFCLQPEPQSQHELGNVFLKFKDKFCVYEEYCSNHEKALRLLMELNKIPAIRAFLLSC
MLLGGRKTTDIPLEGYLLTPIQRICKYPLLLKELAKRTPGKHPDHPAVQSALQAMKTVCT
NINETKRQMEKLEALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFD
NLLVYCKRKSRVTGGKKSAKRTKSINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTV
TNGWKIHNTAKNKWFVCMAKTAEDKQKWLDAIIKEREQRESLKLGMERDAYVMIAEKGEK
LYHMMMSKKVNLIKDRRRKLSTVPKCFLGNEFVAWLIEIGEISKTEEGVNLGQALLENGI
IHHVSDKHQFKNEQVMYRFRYDDGTYKPRSELEDIMSKGVRLYCRLHSLFIPVIKDRDYH
LKTYKSVIPGSKLVDWLLAQGDCQTREEAVALGVGLCNNGFMHHVLEKSEFKDESQYFRF
HADEEMEGTSSKNKLLRNDFKLVENILARSLLILPQEDDYGFDIEEKNKVIVVKSVQRGS
LAEMAGLQVGRKIYSINEDLVFLRPFSEVDAILNQSFCSRRPLRLLVASKAKEIIKVPDH
PETLCFQIRGTSPPYVHAVGRGSEAAAVGLNAGQCILKVNGNNVVNESFVDVLDHFLAYR
SRPQEALGLYQWIYRTHEDAEEARAQQWAPGSYLNGSLDESGGALEGGQDDEDFSLQPMG
PQLPIPEGSPLINLTVENVHLEHGVVYEYVSTAGIKCFVLEKIVEPKGCFALTAKILEAF
AADDSLFVQNCGRLISLSSTVATMPQYEFRNICETKLERITRRIANYQEFAEKLKTRVSP
AFKQASLEPHALCSLDFCPTNCHVNLMEVSYPKNTTSVGRSFSIRFGRKPSLIGLDPEQG
HINPMSYTQHCITTMAAPSWKCLPQEDGEPHERNLMDSTINPQNGGPIQEDRGLSFLLKQ
EDREIQDAYLQLFNKLDVAVKEMKQYVMQINKLLSTITEPTGDGSCEPPSTEEVSPSPLV
SEDSEIDKADHGGIKKVCFKVSEEDQEDSGHDTMSYRDSYSECNSNRDSVLSYTSVRSNS
SYLGSDEMGSGDELPCDMRIPSDKQDKLHGCLEHLFNQVDSINALLKGSVMSKAFEETKH
FPMEHSLQDFKQKEECPIRGRSMIQISIQEDPWNLPNSIKSLVDNIQKYVEDGKNQVLLA
LLKCTDTELQLRRDVIFCQSLVAAICTFSDQLLAALSYRYNNNGEYEESSRDASRKWLEQ
IAATGVLFHYQSLLSPSVKEERAMLEDIRVTLSELDNVTFSFKQLDENFVTNAHVFYHIE
GSRQALKVIFYLDSYHFSKLPTRLENGGSLKLHTVLFTKALENLEGQLQAGGSTTSLLEE
MQQEINAQSLEKVQHYYRRLRTFYLERSNLPTDASATAVKIDQLIRPINAMDELCRLMKS
FVHSKPGTSVPSAGLLPISSELCYRLGACQITMCGTGMQRSTLSVSLEQAAILARSHGLL
PKCIMQATDIMRKQVSLRPQGPGMGHGSHPGIPQI
Download sequence
Identical sequences F6TG39
ENSMODP00000029097 ENSMODP00000029097 XP_007475836.1.35504

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