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Domain assignment for F6W7T9 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  F6W7T9
Domain Number 1 Region: 324-512
Classification Level Classification E-value
Superfamily Regulator of G-protein signaling, RGS 4.88e-66
Family Regulator of G-protein signaling, RGS 0.00000723
Further Details:      
 
Domain Number 2 Region: 715-944
Classification Level Classification E-value
Superfamily DBL homology domain (DH-domain) 1.83e-64
Family DBL homology domain (DH-domain) 0.000000000724
Further Details:      
 
Domain Number 3 Region: 948-1080
Classification Level Classification E-value
Superfamily PH domain-like 3.45e-38
Family Pleckstrin-homology domain (PH domain) 0.00000131
Further Details:      
 
Domain Number 4 Region: 23-113
Classification Level Classification E-value
Superfamily PDZ domain-like 1.22e-19
Family PDZ domain 0.01
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) F6W7T9
Sequence length 1085
Comment (tr|F6W7T9|F6W7T9_HORSE) Rho guanine nucleotide exchange factor 12 {ECO:0000313|Ensembl:ENSECAP00000020327} KW=Complete proteome; Reference proteome OX=9796 OS=Equus caballus (Horse). GN=ARHGEF12 OC=Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Sequence
RHGSILNRESPTDKKQKVERSASHDFDPTGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSV
KEMDGAAMRAGVQTGDRIIKVNGTLVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPL
ADSEVEPSVIGHMSPIMTSPHSPGASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKE
QERLQLLQEDYNRTPAQRLLKEIQEAKKHIPQLQEQLSKATGSAQPLGDALTVSEVEADP
GDGLGRIDYSSGDVSRHSSDNADSPKSGLKERIYLEEPEKSEVNQDIDTQSLIGSPSTRI
APHIIGAEDDDFGTEHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLY
SDLYKQTNSKETRRVFLEFHQFFLDRSAHLKVSVPDEISVDLDKRRPELIPEDLHRHYIQ
TMQEKVHPEVQRHLEDFRQKRSMGLTLAESELTKLDAERDKDRVTLEKERACAEQIVAKI
EEVLMTAQAVEEDKSSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDR
EGEEKGKRRGFPSILGPPRRPSRHDNSAICRAMELQKQRHPKHLSTPSSVSPEPQDPAKL
RQSGLASEGADAGYLPANSTGAAVKFAETNYVENHYRVGETPTSGDSLDGTPRTPNTIFD
FPPPPLDQVQEEEWEVERVTEHETPKPFRKFDSIAFGESQSEDEQFENDLETDPPNWQQL
VSREVLLGLKPCEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIF
SNLEDILQLHIGLNEQMKSVRKRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQP
FALEMIKSRQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTE
WPMEREKVKKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSNLKLSEYPNVEELRN
LDLTKRKMIHEGPLVWKVNRDKTIDLYTLLLDDILVLLQKQDDRLVLRCHSKILASTADS
KHTFSPVIKLNTVLVRQVATGEDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRM
AASVK
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Identical sequences F6W7T9
ENSECAP00000020327

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