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Domain assignment for F6WH53 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  F6WH53
Domain Number 1 Region: 837-1117
Classification Level Classification E-value
Superfamily Protein kinase-like (PK-like) 5.66e-72
Family Protein kinases, catalytic subunit 0.00000429
Further Details:      
 
Domain Number 2 Region: 521-812
Classification Level Classification E-value
Superfamily Protein kinase-like (PK-like) 5.33e-47
Family Protein kinases, catalytic subunit 0.0000758
Further Details:      
 
Domain Number 3 Region: 369-498
Classification Level Classification E-value
Superfamily SH2 domain 4.98e-19
Family SH2 domain 0.003
Further Details:      
 
Domain Number 4 Region: 277-384
Classification Level Classification E-value
Superfamily PH domain-like 5.16e-16
Family Third domain of FERM 0.015
Further Details:      
 
Domain Number 5 Region: 139-259
Classification Level Classification E-value
Superfamily Second domain of FERM 0.0000000576
Family Second domain of FERM 0.0085
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) F6WH53
Sequence length 1130
Comment (tr|F6WH53|F6WH53_MONDO) Tyrosine-protein kinase {ECO:0000256|PIRNR:PIRNR000636, ECO:0000256|RuleBase:RU362096} KW=Complete proteome; Reference proteome OX=13616 OS=Monodelphis domestica (Gray short-tailed opossum). GN=JAK2 OC=Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis.
Sequence
MACLTMTEMEGSATSSTHQNGDIPGNEDTLKQTEPVLQVYLYHSLGKTEGDYLRFPIGEY
IAEEICIAACKACGITPVYHNMFALMSEAERIWYPPNHVFHVDEATRYNVLYRIRFYFPH
WYCNGSNRTYRYGISRGTETPLLDDFVMSYLFAQWREDFVHGWIKVPVTHETQEECLGMA
VLDIMRIAKENDQTPLAVYNSTSYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQQFSQ
CKATARNLKLKYLINLETLQSAFYSEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSRGK
HKDSETLTEQDLQMYCDFPDIIDVSIKQANQEGSNENRVVTIHKQDGKNLEIEFHSLREA
LSFVSLIDGYYRLIADAHHYLCKEVAPPTVLENIQSNCHGPISMDFATSKLKKAGNQTGL
YVLRRSPKDFNTYFLTFAIERESTTDYKHCLITKNENGEFNLSGTKKNFTNLKDLLNCYQ
METVRSDSIIFQFTKCCPPKPKDKSNLLVFRSNGISDVPTSPTLQRHNNVNQMVFHKIRN
EDLIFNESLGQGTFTKIFKGVRREIGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMS
QLSYKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWAMH
FLEEKSLTHGNVCTKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPE
CIENAKNLSLAADKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTELAN
LINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRNGALGFSYAFEDRDPT
QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEIL
KSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERLDHKKLLQYTSQICK
GMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYA
PESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELL
KNNGRLPRPDGCPDEIYSIMTECWNNNVSLRPAFRDLALRVDQIRDDMGG
Download sequence
Identical sequences F6WH53
ENSMODP00000019196 XP_007499600.1.35504 XP_007499601.1.35504 XP_016279730.1.35504 XP_016279731.1.35504 ENSMODP00000019196

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