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Domain assignment for G3TBI9 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  G3TBI9
Domain Number 1 Region: 196-377
Classification Level Classification E-value
Superfamily DBL homology domain (DH-domain) 3.27e-50
Family DBL homology domain (DH-domain) 0.0000119
Further Details:      
 
Domain Number 2 Region: 385-511
Classification Level Classification E-value
Superfamily PH domain-like 1.72e-30
Family Pleckstrin-homology domain (PH domain) 0.00062
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) G3TBI9
Sequence length 619
Comment (tr|G3TBI9|G3TBI9_LOXAF) Rho guanine nucleotide exchange factor 25 {ECO:0000313|Ensembl:ENSLAFP00000011346} KW=Complete proteome; Reference proteome OX=9785 OS=Loxodonta africana (African elephant). GN=ARHGEF25 OC=Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
Sequence
MKPPDRPASGRTDRILGVMGGMLRACALPGQEGPPKRSPLGPGGTEPESDRTEGDQREER
EREAPDWALQPESYSIAGSEGSISASAASGLAAPSGPSSGLSSGPCSPGPPGPISGLRRW
LDHSKHCLSVETEMDGGQAGPYENWMLEPALATGEELPGLTLLTTLLESPRDKTQPAEEE
TASQASESEEEQKKAALERSMYVLSELVETEKMYVEDLGQIVEGYMATMAAQGVPENLRG
RDRIVFGNIQQIYEWHRDYFLQELQKCLEDPDWLAQLFIKHERRLHMYVVYCQNKPKSEH
VVSEFGDSYFEELRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYSRAGMDTEELER
AVEVMCFVPKRCNDMMTLGRLRGFEGKLTAQGKLLGQDTFWVTEPEAGGLLSSRGRERRV
FLFEQIIIFSEALGGGVRGGTQPGYVYKSSIKVSCLGLEGNLQGDSCRFALTSRGPEGGI
QRYVLQATDPAVSQAWIKQVAQILESQRDFLNALQSPIEYQRRESQTNSLGRPGGPGVGS
LGRPRPGDRAQVSTYTPINGSLPSLLLLPKGEVARAPLPLDTQTPSDIPQAPRDSPPVPP
ILNTPPCQARLAKLDEDEL
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Identical sequences G3TBI9
XP_003405207.1.64505 ENSLAFP00000011346 ENSLAFP00000011346

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