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Domain assignment for G3TXL4 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  G3TXL4
Domain Number 1 Region: 42-231
Classification Level Classification E-value
Superfamily Regulator of G-protein signaling, RGS 5.89e-65
Family Regulator of G-protein signaling, RGS 0.0000000225
Further Details:      
 
Domain Number 2 Region: 454-682
Classification Level Classification E-value
Superfamily DBL homology domain (DH-domain) 1.57e-61
Family DBL homology domain (DH-domain) 0.000000548
Further Details:      
 
Domain Number 3 Region: 683-817
Classification Level Classification E-value
Superfamily PH domain-like 6.47e-39
Family Pleckstrin-homology domain (PH domain) 0.0000212
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) G3TXL4
Sequence length 977
Comment (tr|G3TXL4|G3TXL4_LOXAF) Rho guanine nucleotide exchange factor 1 {ECO:0000313|Ensembl:ENSLAFP00000020322} KW=Complete proteome; Reference proteome OX=9785 OS=Loxodonta africana (African elephant). GN=ARHGEF1 OC=Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
Sequence
EEMARGAAPGPPRPGLVPISIIGAEDEDFENELETNAEEQNSQFQSLEQVKRRPVHLIAL
LQHVALQFEPAPLLCCLHADMLSTLGPKEFKKAFIDFYHSFLDKTAVLRVSVPANVAFEL
DRTRPDLISEDIQRRFVQEVVQSQQAAISRQLEDFRSKRLMGMTPWEQELAHLEAWAGRD
RTTYEARERLTAERLLTHLEEMQPTISTDEEKSAAVVNAISVYMRHLGVRTKSGDKKSGR
NFFRKKRPNLNRRPDEPPKTKKGLSSILDAARWNRGEPQVPDFRHLKIEAEADKQGSTER
KGGLAVPSRDRNVGVPGQDTLGVSLHPLSGDSPDREPGVDPPLELGDLPLQGPTNLEPPA
APESTEEGADTERCAGLSGRLGRSESLRVSDRRRPSRGSLGAKGRGGGRSRSDVDMDPSS
ATAVLGPARRATPEPGDEGEPGRLGLELEPEEPPGWRELVPPDTLHSLPKSQVKRQEVIS
ELLVTEAAHVRMLRVLHDLFYQPMAEGGFFPQDELQNIFPSLDELIEVHSLFLDSLMKRR
QDSGYLIEEIGDVLLARFDGAEGTWFQKISSRFCSRQSFALEQLKAKQRKDPRFCAFVQD
AESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQNTEEPAERKKVERAAECCREILHHV
NQAVRDMEDLLRLKDYQRRLDLSHLRQSSDPMLSEFKNLDITKKKLVHEGPLTWRVTKDK
AVEVHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTMLRPVLRLTSAMTREVATDH
KAFYVIFTWDQEAQIYELVAQTVSERKNWCALITETAGSLKVPAPASRPKPPRTSPSSTR
EPLLSSSENSNGGREMPPPDGRMERILSDLLPFCRPGPEGQLAATALQKVLSLKQLLLPV
KEDSGAGPPREGDGVPGGGPLSLSQTQKVQEKLLSLEETVKRLEEMEEEFCRLRLLLSQL
GTLLPSLAAPEDSALTG
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Identical sequences G3TXL4
ENSLAFP00000020322 ENSLAFP00000020322

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