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Domain assignment for H0X540 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  H0X540
Domain Number 1 Region: 216-452
Classification Level Classification E-value
Superfamily DBL homology domain (DH-domain) 4.32e-57
Family DBL homology domain (DH-domain) 0.0000401
Further Details:      
 
Domain Number 2 Region: 452-570
Classification Level Classification E-value
Superfamily PH domain-like 5.87e-31
Family Pleckstrin-homology domain (PH domain) 0.00083
Further Details:      
 
Domain Number 3 Region: 27-91
Classification Level Classification E-value
Superfamily Cysteine-rich domain 0.0000000000000658
Family Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) 0.012
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score

Protein sequence

External link(s) H0X540
Sequence length 987
Comment (tr|H0X540|H0X540_OTOGA) Rho/Rac guanine nucleotide exchange factor 2 {ECO:0000313|Ensembl:ENSOGAP00000010368} KW=Complete proteome; Reference proteome OX=30611 OS=Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby). GN=ARHGEF2 OC=Lorisiformes; Galagidae; Otolemur.
Sequence
MSRIESLTRARIDRSKEPASKTREKEKMREAKDARYTNGHLFTTISVSGMTMCYACNKSI
TAKEALICPTCNVTIHNRCKDTLANCTKVKQKQQKAALLKNNTALQSVSLRSKTTIRERP
SSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLNM
RNRALSVESLIDEGAEVIYNELMSEFEMDEKDFTADSWSLAVDGSFLQQHKKEVMKQQDV
IYELIQTELHHVRTLKIMTRLFRAGMLEELQLEPGVVQGLFPCVDELSDIHMRFLSQLLE
RRRQALSPGSTRNFVIHRLGDLLISQFSGPSAEQMRKTYSEFCSRHTKALKLYKELYARD
KRFQQFIRKVTRSAVLKRHGVQECILLVTQRITKYPVLIGRILQYCHGSEEEHQDLTAAL
GLVKELLSNVDQDVHELEKGARLQEIYNRMDPRAQTPVPGKGPFGREELLRRKLIHDGCL
LWKTATGRFKDVLMLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMF
LISAAPPEMYEVHTASRDDRSTWIRVIQRSVCVCPSREDFPLIETEDEAYLRRIKMELRQ
KDQALVELLQEKVGLFAEMTHFQAEEDGNSGMSLPTLPRGLFRSESLESPRGERLLQDAI
REVESLKDLLVGPGVELLLMPREPALPLELDSGGNTSPGVTANGEARTFNGSIELCRADS
DSSQKDRNGNQLRSPQEEALQRLVNLYGLLHGLQAAVAQQDTLMEARFPEGPERREKLSR
ANSRDGEAGRSGAVPTAPEKQATELALLQRQHALLQEELRRCRRLGEERATEAGSLEARL
RESEQARAVLEREAEEARRQLAALGQTEPLPAEAPWARRPVDPRRRSLPAGDALYLSFNP
PQPSRGPDRLDLPVTIRSSQRPFEDRERQDLGSPEERLQDSSDPDTGSEEEGSSRPSPPH
SPRDFTRMQDIPEETESRDGEPIPSES
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Identical sequences H0X540
ENSOGAP00000010368 ENSOGAP00000010368

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