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Domain assignment for H2UD66 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  H2UD66
Domain Number 1 Region: 191-391
Classification Level Classification E-value
Superfamily DBL homology domain (DH-domain) 4.84e-52
Family DBL homology domain (DH-domain) 0.000000141
Further Details:      
 
Domain Number 2 Region: 2-234
Classification Level Classification E-value
Superfamily Calponin-homology domain, CH-domain 2.49e-39
Family Calponin-homology domain, CH-domain 0.0034
Further Details:      
 
Domain Number 3 Region: 378-544
Classification Level Classification E-value
Superfamily PH domain-like 1.08e-28
Family Pleckstrin-homology domain (PH domain) 0.0092
Further Details:      
 
Domain Number 4 Region: 643-755
Classification Level Classification E-value
Superfamily SH2 domain 8.58e-24
Family SH2 domain 0.00065
Further Details:      
 
Domain Number 5 Region: 785-852
Classification Level Classification E-value
Superfamily SH3-domain 2.23e-21
Family SH3-domain 0.0008
Further Details:      
 
Domain Number 6 Region: 594-672
Classification Level Classification E-value
Superfamily SH3-domain 0.00000000287
Family SH3-domain 0.00047
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) H2UD66
Sequence length 854
Comment (tr|H2UD66|H2UD66_TAKRU) Vav guanine nucleotide exchange factor 1 {ECO:0000313|Ensembl:ENSTRUP00000034885} KW=Complete proteome; Reference proteome OX=31033 OS=Takifugu rubripes (Japanese pufferfish) (Fugu rubripes). GN=VAV1 OC=Takifugu.
Sequence
MELWRQCAAWLIECRVLPDNHRVTWENAQVCDLAQALRDGVLLCQLLNNLLPQAVNLREI
NLRPQMSQFLCLKNIRTFLGVCLAKFYLKKSDLFEAFDLFDVRDFGKVIDTLSILSHSHV
ATQRGLQSFPIEGSNLDEEIYSGLSDYIDETLDEDDDLYDFVEDEEDKGDEIYEDLMKIE
EPPERQKCGVDKRECCLQEIRQTEEKYSETLESVMQHFRKPLERFLQPQDIESIFSNIED
LAKIHRSLLGEVRASILNYGARNLYQVFLDYKERLLLYGSYCSQVEMATKHLDKLSSQRE
DIRMKLEECSNRANSGRFSLRDLLMVPMQRVLKYHLLLQELVKHTTDAKDKENLRLALDA
MRDLAQCVNEVKRDNEIIRQITTFQLSIENMTHSLALYGRPKIDGELKICTPEKKSKHDR
FAFLFDKAMFVCKKKSGETFELKEIIELQSYQIRDEPSGEKDNKKPEQWSHVFLLLDVYG
GTGYDLYFKTRELKKKWLEQFEMALSNLCPENSTANRHDFQMHCFEGTASCKACSMLLRG
IFFQGYRCTRCKMAAHKECLGRVDVCGRNSESIGTIKKHSTVNILMLFATQRSSGYVNPG
FPKMEVCQDYYGLPPPPVGFGQPLHLSKGDIVELTRADADLSWWEGRNLGVGHIGWFPCQ
RVQPYVPRPTPDLSDFPWFAGNLDRAAAKNLLTPRSDGTFLVRQKDGGEFAISIKFNMDI
RHIKITTNDGLFRINDKKAFRGLLELIQFYRQNSLKEYFKEVDTALCTPFKQSEKSNSTN
STSTTPNTTPRGSVKGLSVARARYDYSARDRSELSLQEGDTIKIISKKGHSGWWKGEVYG
RVGLFPANYVDEDF
Download sequence
Identical sequences H2UD66
ENSTRUP00000034885 31033.ENSTRUP00000034885 ENSTRUP00000034885

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