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Domain assignment for I3IUK0 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  I3IUK0
Domain Number 1 Region: 169-374
Classification Level Classification E-value
Superfamily DBL homology domain (DH-domain) 9.29e-52
Family DBL homology domain (DH-domain) 0.0000000527
Further Details:      
 
Domain Number 2 Region: 2-232
Classification Level Classification E-value
Superfamily Calponin-homology domain, CH-domain 3.8e-39
Family Calponin-homology domain, CH-domain 0.0034
Further Details:      
 
Domain Number 3 Region: 379-542
Classification Level Classification E-value
Superfamily PH domain-like 2.89e-30
Family Pleckstrin-homology domain (PH domain) 0.005
Further Details:      
 
Domain Number 4 Region: 632-758
Classification Level Classification E-value
Superfamily SH2 domain 2.63e-24
Family SH2 domain 0.00061
Further Details:      
 
Domain Number 5 Region: 779-838
Classification Level Classification E-value
Superfamily SH3-domain 3.68e-21
Family SH3-domain 0.00071
Further Details:      
 
Domain Number 6 Region: 582-661
Classification Level Classification E-value
Superfamily SH3-domain 0.0000000000975
Family SH3-domain 0.00013
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) I3IUK0
Sequence length 844
Comment (tr|I3IUK0|I3IUK0_ORENI) Vav guanine nucleotide exchange factor 1 {ECO:0000313|Ensembl:ENSONIP00000000290} KW=Complete proteome; Reference proteome OX=8128 OS=Oreochromis niloticus (Nile tilapia) (Tilapia nilotica). GN=VAV1 OC=Pseudocrenilabrinae; Oreochromini; Oreochromis.
Sequence
MELWRQCAMWLIDCRVLPENHRVTLEGAQVCDLAQALRDGVLLCQLLNNLLPQAVNLREI
NLRPQMSQFLCLKNIRTFLGVCQDKFHLKKNELFEAFDLFDVRDFGKVIDTLSTLSHSSI
AVHRGFQPFPLEGCTLDEEIYSGLSDQIDDTVDEDDDLYDFVEDEENEGDEIYEDLMRAD
EPPETQQKTGVDKRECCLQEIRQTEEKYSETLQSILQHFMKPLQRFLQPQDIESIFINIQ
DLAKTHSELLEEVQNSILNNGARNLFQVFVNYKERLLLYGRYCSQVEAATKHLDKLSNAR
EDIRMKLEECSKRANSGRFSLRDLLMVPMQRVLKYHLLLQELVKHTTDSTEKENLRTALD
AMRDLAQSVNEVKRDNEIIKQITTFQLSIENMTQSLALYGRPKIDGELKICSSEKRSKQD
RYAFLFDKAVFICKKKSGETFELKEIIELQSYQIRDETTGEKDNKKWSYLFLLLDCYGRS
GYDLFFKTRELKKKWLEQFEMALSNMSPENSTANNHDFQMYCFEETTSCKACSMLLRGIF
FQGYRCTRCKMAAHKECLGRVPACGRNSDHSVSAKKNKAQRSSGHSSIGYPKMEVNQEYY
GMPPPPVGFGQALNLSRGDVIELTRADAELPWWEGRNLTSGLMGWFPCQKVQPYLSRPTQ
DLSGFNWFAGNMDRTAAKNLLMSRSDGTFLVRQKDGGEYAISIKFNMDIRHIKITSSEGL
YRINDKKAFKGLIEMIQYYQQTSLKEYFKDLDTTLCIPFKQPEQSNLSDNMPNSTPGGSM
RNFGVARARYDFSARDRSELSLREGDTIKILSKKGHSGWWKGEVYGRVGFFPANYVEEDY
SDYC
Download sequence
Identical sequences I3IUK0
ENSONIP00000000290 XP_005462714.1.78416

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