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Domain assignment for M3XWS2 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  M3XWS2
Domain Number 1 Region: 759-986
Classification Level Classification E-value
Superfamily DBL homology domain (DH-domain) 2.36e-60
Family DBL homology domain (DH-domain) 0.00000000132
Further Details:      
 
Domain Number 2 Region: 354-531
Classification Level Classification E-value
Superfamily Regulator of G-protein signaling, RGS 2.09e-54
Family Regulator of G-protein signaling, RGS 0.00000005
Further Details:      
 
Domain Number 3 Region: 990-1124
Classification Level Classification E-value
Superfamily PH domain-like 3.56e-42
Family Pleckstrin-homology domain (PH domain) 0.000000368
Further Details:      
 
Domain Number 4 Region: 39-125
Classification Level Classification E-value
Superfamily PDZ domain-like 4.73e-21
Family PDZ domain 0.029
Further Details:      
 
Weak hits

Sequence:  M3XWS2
Domain Number - Region: 153-163
Classification Level Classification E-value
Superfamily Formin homology 2 domain (FH2 domain) 0.00471
Family Formin homology 2 domain (FH2 domain) 0.13
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score

Protein sequence

External link(s) M3XWS2
Sequence length 1536
Comment (tr|M3XWS2|M3XWS2_MUSPF) Rho guanine nucleotide exchange factor 11 {ECO:0000313|Ensembl:ENSMPUP00000003522} KW=Complete proteome; Reference proteome OX=9669 OS=Mustela putorius furo (European domestic ferret) (Mustela furo). GN=ARHGEF11 OC=Mustelinae; Mustela.
Sequence
MSVRLPQSIDSPTAAWLSSLSLGDPAPERRSPSHRRQPSDASETAGLVQRCVIIQKDQHG
FGFTVSGDRIVLVQSVRPGGAAMRAGVQEGDRIIKVNGTMVTNSSHLEVVKLIKSGAYVA
LTLLGSSPSPVGVSGLQQDPAPTGAPRATPVVPPPPPPPPLPPPQRITGPRPLQDPEFQK
HAAQILRSMLRQEERELQRICEVYSRNPASPLEEQIEGARRRVTQLQLKIQQEMGSGGVD
APLPCGDASQRASEGQLSLDSQEGDSGLDSGTERFPSLNEALLSRNSALSDPGLDSPRTS
PVVMARLAQHHRRQASDTPVPGASDQGTDQSPKPLIIGPEEDYDPGYFNNESDSVFQDLE
KLKARPAHLAVFLRYIFSQADPSPLLFYLCTEVYQQTHPKDSRTLGKDIWNIFLEKNAPL
RVKVPEALQAEIDLRLRTGEDARIALREAQEAAMPEIQEQIQDYRAKRTLGLGSLYGEND
LLGLDGDPVRERQVAEKQLAALADILSKYEEDRSAPMDFALNAYMSHAGLRLREARPSSA
AEKAQAAPDKDKWLPFFPKTKKSSNSKKDKDALEDKRRNPILKYIGKPKSSSQSTFHIPL
SPVEVKPGNVRNIIQHFENNQPYDAPEPGTQRLSTGSFPEDLLESDSSRSEIRLGRSESL
KGREEMKRSRKAENVPRSRSDVDMDAAAEAARLHQSASSSASSLSTRSLENPTPPFTPKM
GRRSIESPSLGFCTDALLPHLLEDDLGQLSDLEPEPDAQNWQHTVGKDVVAGLSQREIDR
QEVINELFVTEASHLRTLRVLDLIFYQRMKKENLMPREELARLFPNLPELIEIHNSWCEA
MRKLREEGPIVKDIGDLMLARFDGPAREELQQVAAQFCSCQTAALGLIKAKQRKESRFQL
FMQEAESHPQCRRLQLRDLIISEMQRLTKYPLLLESVLKHTEGGTPEYEKLCRARDQCRE
ILKYVNEAVKQTENRHRLEGYQKRLDTTSLERASNPLAAEFKSLDLTARRMVHEGPLSWR
ISKDKSLDLHVLLLEDLLVLLQRQDEKLLLKCHSKTAAGSSDSKQTFSPVLKLNAVLVRS
VATDKRAFFVICTSELGPPQIYELVALTSSDKNTWMELLEEAVRNATRRPGGAPALAHPP
PPGTQAPAQQSPTPSRVQLDGSEVFHSEPEELPGAGPGPQQRARGTHPVLPEDSEREGSL
EEELGALPHPSTSADGEHRGGRTRDPILLPLPGPLFTEGLADSALEDVESLRHLILESLL
QGQRPEDDLTPTPSLGSSTCHPADPGSPGHGLLGVEEPEQGDAALRSLEQLPPRARNSGI
WESPELDRNPEEEAPSAEATGRYQVVRKAGGGTDAAEVAGSKARLPESGRSGPEPPDVEG
GAEAAGNCFYVSMLAGPPDSSTEPSQPDSLPAWQPWGSRGGRRRPSHSAPSLALRDVGSI
FHTIEQLTVKLNRLKDVELAHRELLRSLAGESGGTTPVGSFHTEAAGWTDSSLSPPARET
LASDSRDSHQPGPCSEDGSDTALEDGTALTASSPGL
Download sequence
Identical sequences M3XWS2
ENSMPUP00000003522 XP_004778518.1.14098 ENSMPUP00000003522

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