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Domain assignment for M3XZH2 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  M3XZH2
Domain Number 1 Region: 166-368
Classification Level Classification E-value
Superfamily DBL homology domain (DH-domain) 6.15e-56
Family DBL homology domain (DH-domain) 0.00021
Further Details:      
 
Domain Number 2 Region: 351-484
Classification Level Classification E-value
Superfamily PH domain-like 8.56e-30
Family Pleckstrin-homology domain (PH domain) 0.0028
Further Details:      
 
Domain Number 3 Region: 462-502,541-599
Classification Level Classification E-value
Superfamily FYVE/PHD zinc finger 5.28e-21
Family FYVE, a phosphatidylinositol-3-phosphate binding domain 0.0042
Further Details:      
 
Domain Number 4 Region: 630-727
Classification Level Classification E-value
Superfamily PH domain-like 2.77e-16
Family Pleckstrin-homology domain (PH domain) 0.0000595
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) M3XZH2
Sequence length 736
Comment (tr|M3XZH2|M3XZH2_MUSPF) FYVE, RhoGEF and PH domain containing 3 {ECO:0000313|Ensembl:ENSMPUP00000004473} KW=Complete proteome; Reference proteome OX=9669 OS=Mustela putorius furo (European domestic ferret) (Mustela furo). GN=FGD3 OC=Mustelinae; Mustela.
Sequence
MESGGGASTAQPPIAALGELNSGPGCSSPELSRADPGKLQALPLGPRAHGKDSDPGSPGS
PAAAGDGPPDTGPSGELDGGAKLPNRDSGIDSPSCSVANEQFPCGEGSEAGQGPTVLGPQ
LDGAPEGKALQEVADSDVGEGSGEEPDPENSPPGDLADPAKCSEPPKLLHIAQELLHTEE
TYVRRLYLLDQVFCTQLTEAGIPSEVTTGIFSNISSIYRFHGHFLLPELQTRITQEWDTN
PRLGDILQKLAPFLKMYGEYVKNFDRAMELVSAWTQRSPVFKDVVHRIQKQEVCGNLTLQ
HHMLEPVQRVPRYQLLLKDYLKRLPGDAPDRKDAERSLELISTAANHSNAAIRKMEKMHK
LLEVYERLGGEEDIVNPANELIKEGPIQKLSAKNGTAQDRHLFLFNSMILYCVPKLRLMG
QKFSVREKMDISGLQVQDIVKPNAAPTFIITGRRRCLELQTRTEEEKKEWIQVIEATIER
HKQNSQTFKAFSGSFGQEEDPSLPPDSPVVGSSSEGPAVAASGGGGTAGPEPRRGSGKTR
RDKEKQGCRSCGETFNSITKRKHRCKLCGAVICGKCSEFKAENGRQSRVCRECFLTQQAV
PESPSPEAVPEEPKHGTENPVSVDPQPSMLCSSLQVSDSGVVWSEVWATIPASEPLELVL
HLQRDSQDGGPPRTIPLAGCTVSVLDPVERPDSRHVWRLQQAQQTLYLSTPSADLRQQWL
EALSAAARGDPGLVAL
Download sequence
Identical sequences M3XZH2
ENSMPUP00000004473 XP_004766190.1.14098 XP_004766191.1.14098 XP_004766192.1.14098 ENSMPUP00000004473

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