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Domain assignment for M3Y0Y2 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  M3Y0Y2
Domain Number 1 Region: 565-1037
Classification Level Classification E-value
Superfamily Ras GEF 2.48e-135
Family Ras GEF 0.000000000000385
Further Details:      
 
Domain Number 2 Region: 7-177
Classification Level Classification E-value
Superfamily Histone-fold 3.07e-51
Family TBP-associated factors, TAFs 0.000000255
Further Details:      
 
Domain Number 3 Region: 204-393
Classification Level Classification E-value
Superfamily DBL homology domain (DH-domain) 1.7e-40
Family DBL homology domain (DH-domain) 0.000000195
Further Details:      
 
Domain Number 4 Region: 416-571
Classification Level Classification E-value
Superfamily PH domain-like 2.26e-37
Family Pleckstrin-homology domain (PH domain) 0.00000138
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score

Protein sequence

External link(s) M3Y0Y2
Sequence length 1281
Comment (tr|M3Y0Y2|M3Y0Y2_MUSPF) SOS Ras/Rho guanine nucleotide exchange factor 2 {ECO:0000313|Ensembl:ENSMPUP00000004983} KW=Complete proteome; Reference proteome OX=9669 OS=Mustela putorius furo (European domestic ferret) (Mustela furo). GN=SOS2 OC=Mustelinae; Mustela.
Sequence
MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPTLSANEESLSYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYQVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPTSSGELNYYDLIRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDI
DRIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPKFNEHFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEDQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG
YSSAEYRLKEKFVMRKIQICDKDDTCEYKNAFELVSKDENSIIFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPDVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA
IEKGEQPVSADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAILSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRILD
DAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKMSFSRIAETDLESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDHDASNSKGNTKSDDDPPAIPPRQPPPPKPPPLGHLHRDPDWFRD
VSTCPNSPNTPPSTPSPRVPRRCYMLSSSHNNLAHPQAPPVPPRQNSSPHLPKLPPKTYK
RELSHPPSYRLPLLENAETPQ
Download sequence
Identical sequences M3Y0Y2
ENSMPUP00000004983 ENSMPUP00000004983

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