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Domain assignment for M3Y2L2 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  M3Y2L2
Domain Number 1 Region: 370-558
Classification Level Classification E-value
Superfamily Regulator of G-protein signaling, RGS 5.38e-66
Family Regulator of G-protein signaling, RGS 0.00000793
Further Details:      
 
Domain Number 2 Region: 768-997
Classification Level Classification E-value
Superfamily DBL homology domain (DH-domain) 6.02e-63
Family DBL homology domain (DH-domain) 0.000000000968
Further Details:      
 
Domain Number 3 Region: 1001-1131
Classification Level Classification E-value
Superfamily PH domain-like 4.92e-39
Family Pleckstrin-homology domain (PH domain) 0.00000125
Further Details:      
 
Domain Number 4 Region: 69-149
Classification Level Classification E-value
Superfamily PDZ domain-like 7.49e-22
Family PDZ domain 0.01
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) M3Y2L2
Sequence length 1544
Comment (tr|M3Y2L2|M3Y2L2_MUSPF) Rho guanine nucleotide exchange factor 12 {ECO:0000313|Ensembl:ENSMPUP00000005563} KW=Complete proteome; Reference proteome OX=9669 OS=Mustela putorius furo (European domestic ferret) (Mustela furo). GN=ARHGEF12 OC=Mustelinae; Mustela.
Sequence
MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERSASHDFDPTDSSSKKTKSSSEE
SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT
LVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEPSVVGHMSPIMTSPHSPG
ASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQ
EAKKHIPQLQEQLSKATGSAQDGAVVTSSRPLGDPLPVSEAEADPGDGLGRIDYSSGDAS
RPSSDSADSPKSSLKERICLEENPEKSEAIQDPDTQSLIGSPSPRVAPHIIGAEDDDFGT
EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKQTNSKETRR
VFLEFHQFFLDRSAHLKVSVPDEISVDLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHL
EDFRQKRSMGLTLAESELTKLDAEREKDRVTLEKERACAEQIVAKIEEVLMTAQAVEEDK
SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDREGEEKGKRRGFPSI
LGPPRRPSRHDNSAIGRAMELQKQRHPKHLSTPSSVSPEPPDPAKLRQSGLAGEGTDVGY
LPANSMSSVAAGATLAQEGGGKENDTGSKQAGETAASGDCVDSTPRTPNTVFDFPPPPLD
QVQEEEWEVERVTEHGTPKPFRKFDSIAFGESQSEDEQFENDLETDPPNWQQLVSREVLL
GLKPSEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDIL
QLHIGLNEQMKAVRKRNETSVIDQIGEDLLIWFSGPGEDKLKHAAATFCSNQPFALEMIK
SRQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTELPMEREK
VKKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSNLKLSEYPNVEELRNLDLTKRK
MIHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPV
IKLNTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSA
KPIPLPQSSPCEGDNDEETAPKLKVEHHSISVPGLQSPDRDLGLESPLISSKPQSHSLGT
SGKSEVDDLFVAERQLVKEQQEDGTLQEAGASYQTPGPDPHLPASDERWALDALRNLGLL
KQLLVQQLGLTEKSSQEDWPHFPRYRTASSGVQTDSGAQNSENSKAYPPGEGHMPFRTGT
GDAAPCYSPRTSAESSTPRDSVVLAFQDSQASNILVMDHMLRTPEMPPAEPEGSLDESGE
HFFDAREAHSDDNPSEGDGAVKKEEDVNLRISGNYLILDGYDAVQESSTDEGLASSLPLP
PTTGTPSTDSARPQQHSPQHTHSDGAASPFSPEFLVQQRWGAMEDSCFEIQSPPSCADSQ
SQIMEYIRKIEADLEHLKKVEESYSTLCQRLAGSALTDKHSDKS
Download sequence
Identical sequences M3Y2L2
ENSMPUP00000005563 XP_004750127.1.14098 ENSMPUP00000005563

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