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Domain assignment for M3Y379 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  M3Y379
Domain Number 1 Region: 829-1064
Classification Level Classification E-value
Superfamily DBL homology domain (DH-domain) 6.67e-57
Family DBL homology domain (DH-domain) 0.000033
Further Details:      
 
Domain Number 2 Region: 1061-1190
Classification Level Classification E-value
Superfamily PH domain-like 7.67e-35
Family Pleckstrin-homology domain (PH domain) 0.001
Further Details:      
 
Domain Number 3 Region: 648-700
Classification Level Classification E-value
Superfamily Cysteine-rich domain 0.000000000000404
Family Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) 0.011
Further Details:      
 
Weak hits

Sequence:  M3Y379
Domain Number - Region: 136-220
Classification Level Classification E-value
Superfamily Ankyrin repeat 0.00068
Family Ankyrin repeat 0.011
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score

Protein sequence

External link(s) M3Y379
Sequence length 1703
Comment (tr|M3Y379|M3Y379_MUSPF) Rho guanine nucleotide exchange factor 28 {ECO:0000313|Ensembl:ENSMPUP00000005780} KW=Complete proteome; Reference proteome OX=9669 OS=Mustela putorius furo (European domestic ferret) (Mustela furo). GN=ARHGEF28 OC=Mustelinae; Mustela.
Sequence
MELSCGEVPLYGQKTVYAKFGKNVYLPKDAEFYFIYSGSHQRHIVIAERAEDNVLQSSIP
GHGLQETVTVSVCLCSEGYSPVTMGSGSVTYVDTMACRLARLLVTQADRLTADSHQTLLT
PFALTVGALPALDEEFVLALTHLELPLEWTVLGISSLEVSLCRESLLHLAMRWGLPKLSH
FLLCLPGGVQALSLPNEEGATPLDLALQAGHSKLVEDITNFQGRRTLGFSRVQLSEQAFL
QYLHSSETLTLTLNHTAEHLLEADIKLFRKYYWDRAFLLKTLEDQEARPEERGDKPSSAA
ETEEEIKNLATSRSSPEKENVKHMENLVVQPNEHGDRDRLDLDHSSDVFKKSKHPPTFFG
VGRLSEVLNGGDEVYANCMVIDQVGDLDINYVNIEGIMTEVCPESMGSTLGPQNCKHILD
AENSHGKCPLNENKEVTSNTEAQQSPSPSSSYASKYNLSFGHRGFEKEQSHLKKRSSSLD
ALDADSEGEGRSEPARICYTPVSQSSSRTGIPSGDELDSFETTTEPDFSISRTESLSLSS
NLPLKESLLSGVRSRSYSCSSPKISLGKTRLVRDFTVCSSSEEQRAYSLPEPPREKRIQE
EEWDKYIIPAKSESEKYKVSRTFSFLMNRMTSPRNKSKTKSKDAKDKEKLSRHQFVPGTF
SGVLQCSVCDKTLLGKESFQCSNCNTNVHKGCKDAAPPCTKKFQEKYNKNKPQTILGNSS
FRDIPQPGLSLHPSSSMPIGLPTRRKEASAQAHPLSRSVPGTTLESFRRSGPSLESESDG
NTWRSRSHSDELLQSMGSSPSTESFLMEDVVDSSLWSDLSSDAQELEAESWSLVVDPSFC
SKQEKDVIKRQDVIFELMQTEMHHIQTLLIMSEIFRKGMKEELQLDHSTVDKIFPCLDEL
LEIHRHFFYSMKERRQESCAGDDRNFIINRIGDILVQQFSEENANQMKKIYGEFCSHHKE
AVSLFKELQQNKKFQNFIKLRNSNLLARRRGIPECILLVTQRITKYPVLVERILQYTKER
SEEHKDLCKALGLIKDMIAAVDLKVSEYEKNQKWLEILNKIENKTYTKLKNGHVFRKQAL
ISKERTLLHDGLVYWKTATGRFKDILALLLTDVLLFLQEKDQKYIFAAVDQKPSVISLQK
LIAREVANEERGMFLISASSAGPEMYEIHTNSKEERNNWMRRIQQAVESCPEEEGGRTSE
SDEERRKAEARVAKIQQCQEILSNQDQQICTCLEEKLHIYAELGELSGLEDVHLEPHLLI
KPDPGEPPQAASLLAAALKEAESLQVAVKATQAGDACQSSEEGSGESSLTDTRSTPEEPG
SSPASLVTEGTGGRGCWDVDPGTQGLGTDLAVSDAGEKVEYRSFPVSSQSEIIQAIQNLT
RLLYSLQAALTIQDSHIQVHRLLLQQQESLSPGPSFRGSPFQDQEKYRNLEKQREELANI
HKLQSQFQQDQRRWHRQCDQQQREQEAKASRLQERERECRSQEELLLRTRGELDQQLQEY
QQNLERLREGQRLVERERERMRAQQSLLCGWKHGRQSSLPAAFSPGSIEVMELNRSESLC
HENSFFVNEALVQMSLNPYNQSTLSGVHQDATYPQNIANSDLVRTSENQVDLQLDISQPL
DVNHELWTATGSCHQIPPLHPSSKDSCKNDLDNSQTEFPTPHDSNPPGSQLQTFMAEAKL
NLQTLTRQDGETGDGAEENIVYL
Download sequence
Identical sequences M3Y379
ENSMPUP00000005780 ENSMPUP00000005780 XP_012919131.1.14098 XP_012919132.1.14098 XP_012919133.1.14098 XP_012919134.1.14098

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