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Domain assignment for O14543 from Uniprot 2018_03 genome

Domain architecture

Domain assignment details

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Strong hits

Sequence:  O14543
Domain Number 1 Region: 32-129
Classification Level Classification E-value
Superfamily SH2 domain 3.5e-23
Family SH2 domain 0.00027
Further Details:      
Domain Number 2 Region: 176-223
Classification Level Classification E-value
Superfamily SOCS box-like 0.000000000536
Family SOCS box-like 0.0032
Further Details:      

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score

Protein sequence

External link(s) O14543
Sequence length 225
Comment (sp|O14543|SOCS3_HUMAN) STAT-induced STAT inhibitor 3 KW=Complete proteome; Reference proteome OX=9606 OS=Homo sapiens (Human). GN=SOCS3; OC=Catarrhini; Hominidae; Homo.
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Identical sequences A0A096N6K0 A0A0D9SCG7 A0A2I2YFI0 A0A2K5HIR1 A0A2K5KJY7 A0A2K5UBZ8 A0A2K6AQN1 F6UUY8 H2NUW5 H2QDZ6 O14543 Q6FI39
ENSP00000330341 ENSPANP00000008102 gi|45439352|ref|NP_003946.3| NP_003946.3.87134 NP_003946.3.92137 XP_001157032.1.37143 XP_002827937.1.23681 XP_003818320.1.60992 XP_004040931.1.27298 XP_005585187.1.63531 XP_008011284.1.81039 XP_011718359.1.29376 XP_011810920.1.43180 XP_011897648.1.92194 ENSPPYP00000009756 ENSPTRP00000016513 ENSGGOP00000015901 ENSP00000330341 ENSP00000330341 ENSGGOP00000015901 ENSPPYP00000009756 9598.ENSPTRP00000016513 9600.ENSPPYP00000009756 9606.ENSP00000330341 GO.35335 HR3017 ENSPTRP00000016513

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