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Domain assignment for P00742 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  P00742
Domain Number 1 Region: 145-174,227-467
Classification Level Classification E-value
Superfamily Trypsin-like serine proteases 1.79e-81
Family Eukaryotic proteases 0.00000000601
Further Details:      
 
Domain Number 2 Region: 40-103
Classification Level Classification E-value
Superfamily GLA-domain 4.37e-26
Family GLA-domain 0.0000618
Further Details:      
 
Domain Number 3 Region: 93-124
Classification Level Classification E-value
Superfamily EGF/Laminin 0.0000167
Family EGF-type module 0.001
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) P00742
Sequence length 488
Comment (sp|P00742|FA10_HUMAN) Activated factor Xa heavy chain KW=Complete proteome; Reference proteome OX=9606 OS=Homo sapiens (Human). GN=F10; OC=Catarrhini; Hominidae; Homo.
Sequence
MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEE
TCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKN
CELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERR
KRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQE
CKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGE
AVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGI
VSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSG
GPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPE
VITSSPLK
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Identical sequences H2Q7T9 P00742 Q5JVE7
gi|4503625|ref|NP_000495.1| ENSP00000386320 ENSPTRP00000010286 ENSP00000364709 NP_000495.1.87134 NP_000495.1.92137 XP_003832150.1.60992 XP_016781085.1.37143 XP_509746.2.37143 ENSP00000364709 9598.ENSPTRP00000010286 9606.ENSP00000364709 ENSPTRP00000010286

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