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Domain assignment for P26012 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  P26012
Domain Number 1 Region: 143-386
Classification Level Classification E-value
Superfamily vWA-like 4e-77
Family Integrin A (or I) domain 0.000000549
Further Details:      
 
Domain Number 2 Region: 387-473
Classification Level Classification E-value
Superfamily Integrin domains 1.52e-20
Family Integrin domains 0.0013
Further Details:      
 
Domain Number 3 Region: 44-102
Classification Level Classification E-value
Superfamily Plexin repeat 0.00000000000157
Family Plexin repeat 0.00072
Further Details:      
 
Domain Number 4 Region: 591-630
Classification Level Classification E-value
Superfamily EGF/Laminin 0.0000000276
Family Integrin beta EGF-like domains 0.0056
Further Details:      
 
Domain Number 5 Region: 547-585
Classification Level Classification E-value
Superfamily EGF/Laminin 0.000000586
Family Integrin beta EGF-like domains 0.051
Further Details:      
 
Weak hits

Sequence:  P26012
Domain Number - Region: 510-547
Classification Level Classification E-value
Superfamily EGF/Laminin 0.00206
Family Integrin beta EGF-like domains 0.02
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score

Protein sequence

External link(s) P26012
Sequence length 769
Comment (sp|P26012|ITB8_HUMAN) Integrin beta-8 KW=Complete proteome; Reference proteome OX=9606 OS=Homo sapiens (Human). GN=ITGB8; OC=Catarrhini; Hominidae; Homo.
Sequence
MCGSALAFFTAAFVCLQNDRRGPASFLWAAWVFSLVLGLGQGEDNRCASSNAASCARCLA
LGPECGWCVQEDFISGGSRSERCDIVSNLISKGCSVDSIEYPSVHVIIPTENEINTQVTP
GEVSIQLRPGAEANFMLKVHPLKKYPVDLYYLVDVSASMHNNIEKLNSVGNDLSRKMAFF
SRDFRLGFGSYVDKTVSPYISIHPERIHNQCSDYNLDCMPPHGYIHVLSLTENITEFEKA
VHRQKISGNIDTPEGGFDAMLQAAVCESHIGWRKEAKRLLLVMTDQTSHLALDSKLAGIV
VPNDGNCHLKNNVYVKSTTMEHPSLGQLSEKLIDNNINVIFAVQGKQFHWYKDLLPLLPG
TIAGEIESKAANLNNLVVEAYQKLISEVKVQVENQVQGIYFNITAICPDGSRKPGMEGCR
NVTSNDEVLFNVTVTMKKCDVTGGKNYAIIKPIGFNETAKIHIHRNCSCQCEDNRGPKGK
CVDETFLDSKCFQCDENKCHFDEDQFSSESCKSHKDQPVCSGRGVCVCGKCSCHKIKLGK
VYGKYCEKDDFSCPYHHGNLCAGHGECEAGRCQCFSGWEGDRCQCPSAAAQHCVNSKGQV
CSGRGTCVCGRCECTDPRSIGRFCEHCPTCYTACKENWNCMQCLHPHNLSQAILDQCKTS
CALMEQQHYVDQTSECFSSPSYLRIFFIIFIVTFLIGLLKVLIIRQVILQWNSNKIKSSS
DYRVSASKKDKLILQSVCTRAVTYRREKPEEIKMDISKLNAHETFRCNF
Download sequence
Identical sequences P26012
ENSP00000222573 ENSP00000222573 NP_002205.1.87134 NP_002205.1.92137 XP_016867667.1.92137 XP_016867668.1.92137 gi|4504779|ref|NP_002205.1| 9606.ENSP00000222573 ENSP00000222573

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