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Domain assignment for Q8N2E2 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  Q8N2E2
Domain Number 1 Region: 1182-1228
Classification Level Classification E-value
Superfamily EGF/Laminin 0.00000155
Family EGF-type module 0.015
Further Details:      
 
Domain Number 2 Region: 1361-1394
Classification Level Classification E-value
Superfamily EGF/Laminin 0.0000328
Family EGF-type module 0.021
Further Details:      
 
Weak hits

Sequence:  Q8N2E2
Domain Number - Region: 1490-1521
Classification Level Classification E-value
Superfamily EGF/Laminin 0.000984
Family EGF-type module 0.025
Further Details:      
 
Domain Number - Region: 1522-1554
Classification Level Classification E-value
Superfamily EGF/Laminin 0.000984
Family EGF-type module 0.041
Further Details:      
 
Domain Number - Region: 1426-1456
Classification Level Classification E-value
Superfamily EGF/Laminin 0.0019
Family EGF-type module 0.025
Further Details:      
 
Domain Number - Region: 1554-1585
Classification Level Classification E-value
Superfamily EGF/Laminin 0.00437
Family EGF-type module 0.024
Further Details:      
 
Domain Number - Region: 1458-1484
Classification Level Classification E-value
Superfamily EGF/Laminin 0.00802
Family EGF-type module 0.02
Further Details:      
 
Domain Number - Region: 1394-1425
Classification Level Classification E-value
Superfamily EGF/Laminin 0.0113
Family EGF-type module 0.029
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) Q8N2E2
Sequence length 1590
Comment (sp|Q8N2E2|VWDE_HUMAN) von Willebrand factor D and EGF domain-containing protein KW=Complete proteome; Reference proteome OX=9606 OS=Homo sapiens (Human). GN=VWDE; OC=Catarrhini; Hominidae; Homo.
Sequence
MPGGACVLVIALMFLAWGEAQECSPGGHQFLRSPYRSVRFDSWHLQQSAVQDLICDHSLS
PGWYRFLILDRPAEMPTKCVEMNHCGTQAPIWLSLRDSETLPSPGEIKQLTACATWQFLF
STTKDCCLFQIPVSVRNCGNFSVYLLQPTQGCMGYCAEAISDARLHPCGSDETETGGDCV
RQLAASLPPPPAGRPEVLVELIESRLFCRCSFDVPATKNSVGFHIAWSRLSSQEVKEELT
QETTVQAFSLLELDGINLRLGDRIFCSASVFFLENPHVQSVAIESQEFFAGFKLQPELST
ISEDGKEYYLRIESTVPIICSEFSELDQECKISLKLKTIGQGREHLGLNLALSSCHVDLL
QTSSCANGTCSHTFVYYTAVTDFSRDGDRVSNIVVQPIVNEDFLWNNYIPDSIQIKVKDV
PTAYCYTFTDPHIITFDGRVYDNFKTGTFVLYKSMSRDFEVHVRQWDCRSLHYPVSCNCG
FVAQEGGDIVTFDMCNGQLRESQPYLFIKSQDVTRNIKISESYLGRKVTIWFSSGAFIRA
DLGEWGMSLTIRAPSVDYRNTLGLCGTFDENPENDFHDKNGMQIDQNFNNYVAFINEWRI
LPGKSMSDTLPVSMTSPGKPSYCSCSLDTAAYPSSEDLDSVSRSEIALGCKDLNHVSLSS
LIPELDVTSEYINSDTLVREINKHTSPEEYNLNLFLQEKKHINLTKLGLNVQKHPGNEKE
DSLQYLANKKYTQGRGSHSQEMRYNRQNRWKRQNFHEFPPLFAFPSLSQTDLEELTYFFP
EDHAEDVQQEFFPSWPTPSGLTEYSTLTLCQETLANSSIGRLCLAFLGKRLDSVIEMCVK
DVLLKDDLSWAEAGVALLENECEKRIVEEGKYNTEEYGTSIEDILSVLKCPNLCSGNGQC
MEWGCACSPSFSSYDCSDSYDKAPEITELGNAGFCDVQKYNCMMVRVFGKGFKELPSIKC
EVTKLQYNSSEWMPGEPIYTQTVFHNSRAVDCQLPTDVQQFDTMDLVGGKPTGKWQLKVS
NDGYKFSNPKITVIYDGACQVCGLYKNDSCTIKENVCIIDGLCYVEGDKNPTSPCLICRP
KISRFTWSFLENNQPPVIQALQDKLQTFYGENFEYQFVAFDPEGSDIHFTLDSGPEGASV
SSAGLFMWKTDLLTTQQITVRLNDDCDAETRVTIEVTVKSCDCLNGGSCVSDRNFSPGSG
VYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFHSYSCDCPPELKVETQFVNQFTTQ
TVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYPCGKSRECVAPNICKCKPGY
IGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTC
PYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTALCDPVCLNGGSCNKPN
TCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRFQKSICDPTCMNGGKC
VGPSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSICHCPSSWEGVRCQIPICNPKCLY
GGRCIFPNVCSCRTEYSGVKCEKKIQIRRH
Download sequence
Identical sequences Q8N2E2
9606.ENSP00000401687 ENSP00000275358 gi|209571555|ref|NP_001129396.1| ENSP00000275358 ENSP00000275358 NP_001129396.1.87134 NP_001129396.1.92137

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