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Domain assignment for Q9HC29 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  Q9HC29
Domain Number 1 Region: 761-1030
Classification Level Classification E-value
Superfamily RNI-like 2.75e-59
Family 28-residue LRR 0.0052
Further Details:      
 
Domain Number 2 Region: 34-111
Classification Level Classification E-value
Superfamily DEATH domain 0.00000000000000287
Family Caspase recruitment domain, CARD 0.0052
Further Details:      
 
Domain Number 3 Region: 132-214
Classification Level Classification E-value
Superfamily DEATH domain 0.000000000000753
Family Caspase recruitment domain, CARD 0.0061
Further Details:      
 
Domain Number 4 Region: 294-475
Classification Level Classification E-value
Superfamily P-loop containing nucleoside triphosphate hydrolases 0.000000065
Family G proteins 0.077
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) Q9HC29
Sequence length 1040
Comment (sp|Q9HC29|NOD2_HUMAN) Inflammatory bowel disease protein 1 KW=Complete proteome; Reference proteome OX=9606 OS=Homo sapiens (Human). GN=NOD2; OC=Catarrhini; Hominidae; Homo.
Sequence
MGEEGGSASHDEEERASVLLGHSPGCEMCSQEAFQAQRSQLVELLVSGSLEGFESVLDWL
LSWEVLSWEDYEGFHLLGQPLSHLARRLLDTVWNKGTWACQKLIAAAQEAQADSQSPKLH
GCWDPHSLHPARDLQSHRPAIVRRLHSHVENMLDLAWERGFVSQYECDEIRLPIFTPSQR
ARRLLDLATVKANGLAAFLLQHVQELPVPLALPLEAATCKKYMAKLRTTVSAQSRFLSTY
DGAETLCLEDIYTENVLEVWADVGMAGPPQKSPATLGLEELFSTPGHLNDDADTVLVVGE
AGSGKSTLLQRLHLLWAAGQDFQEFLFVFPFSCRQLQCMAKPLSVRTLLFEHCCWPDVGQ
EDIFQLLLDHPDRVLLTFDGFDEFKFRFTDRERHCSPTDPTSVQTLLFNLLQGNLLKNAR
KVVTSRPAAVSAFLRKYIRTEFNLKGFSEQGIELYLRKRHHEPGVADRLIRLLQETSALH
GLCHLPVFSWMVSKCHQELLLQEGGSPKTTTDMYLLILQHFLLHATPPDSASQGLGPSLL
RGRLPTLLHLGRLALWGLGMCCYVFSAQQLQAAQVSPDDISLGFLVRAKGVVPGSTAPLE
FLHITFQCFFAAFYLALSADVPPALLRHLFNCGRPGNSPMARLLPTMCIQASEGKDSSVA
ALLQKAEPHNLQITAAFLAGLLSREHWGLLAECQTSEKALLRRQACARWCLARSLRKHFH
SIPPAAPGEAKSVHAMPGFIWLIRSLYEMQEERLARKAARGLNVGHLKLTFCSVGPTECA
ALAFVLQHLRRPVALQLDYNSVGDIGVEQLLPCLGVCKALYLRDNNISDRGICKLIECAL
HCEQLQKLALFNNKLTDGCAHSMAKLLACRQNFLALRLGNNYITAAGAQVLAEGLRGNTS
LQFLGFWGNRVGDEGAQALAEALGDHQSLRWLSLVGNNIGSVGAQALALMLAKNVMLEEL
CLEENHLQDEGVCSLAEGLKKNSSLKILKLSNNCITYLGAEALLQALERNDTILEVWLRG
NTFSLEEVDKLGCRDTRLLL
Download sequence
Identical sequences Q9HC29
ENSP00000300589 NP_071445.1.87134 NP_071445.1.92137 gi|11545912|ref|NP_071445.1| ENSP00000300589 9606.ENSP00000300589 ENSP00000300589 NYSGRC-11545912

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