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Domain assignment for W5PZS2 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  W5PZS2
Domain Number 1 Region: 258-466
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 1.39e-54
Family Reprolysin-like 0.00079
Further Details:      
 
Domain Number 2 Region: 559-613
Classification Level Classification E-value
Superfamily TSP-1 type 1 repeat 0.000000000000196
Family TSP-1 type 1 repeat 0.0007
Further Details:      
 
Domain Number 3 Region: 866-922
Classification Level Classification E-value
Superfamily TSP-1 type 1 repeat 0.0000000772
Family TSP-1 type 1 repeat 0.0068
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) W5PZS2
Sequence length 922
Comment (tr|W5PZS2|W5PZS2_SHEEP) ADAM metallopeptidase with thrombospondin type 1 motif 5 {ECO:0000313|Ensembl:ENSOARP00000015958} KW=Complete proteome; Reference proteome OX=9940 OS=Ovis aries (Sheep). GN=ADAMTS5 OC=Pecora; Bovidae; Caprinae; Ovis.
Sequence
MLLGWASLMLCALRLPPVAAGPAAAPAQDKAGQPRAAAVAAAAQPRGWRGEEAQEPAEPP
GHPHPLAPQRGSRGLVQNIDQLYSGGGKVGYLVYAGGRRFLLDLERDDSVGAAGLVPAGG
GPNATRRHRGHCFYRGTVDGSSRSLAVFDLCGGLDGFFAVKRARYTWQPLLRGPWAEAED
DARVYGDGSPRILHVYTREGFSFEALPPRTSCETHASPPGARERPPAPRRQDGRWALAPQ
QLPGQSAPCRRRLHLPGPRQVELLLVADASMARMYGRGLQHYLLTLASIANKLYSHASIE
NHIRLVVVKVVVLGDKDKSLEVSKNAATTLKNFCKWQHQHNQLGDDHEEHYDAAILFTRE
DLCGHHSCDTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGHLLGLSHDDSKFCEE
NFGSTEDKRLMSSILTSIDASKPWSKCTSATITEFLDDGHGNCLLDLPRKQIPGPEELPG
QTYDASQQCNLTFGPEYSVCPGMDVCARLWCAVVRQGQMVCLTKKLPAVEGTPCGKGRIC
LQGKCVDKTKKKYYSTSSHGNWGSWGSWGQCSRSCGGGVQFAYRHCNNPAPRNHGRYCTG
KRAVYRSCSVTPCPANDKSFRHEQCEAKNGYQSDAKGVKTFVEWVPKYAGVLPGDVCKLT
CRAKGTGYYVVFSPKVTDGTECRPYSNSVCVRGKCVRTGCDGIIGSKLQYDKCGVCGGDN
SSCTKVVGTFNKKSKGYTDVVRIPEGATHIKVRQFKAKDQTRFTAYLALKKKNGEYLING
KYMISTSETIIDINGTVMNYSGWSHRDDFLHGMGYSATKEILIVQILATDPTKALDVRYS
FFVPKKSAPKANSVTSQGSNKVGSPTPQLQWVTGPWLACSRTCDTGWHTRTVQCQDGNRK
LAKGCLLSQRPSAFKQCLLKKC
Download sequence
Identical sequences W5PZS2
ENSOARP00000015958

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