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Domain assignment for D2IE12_9PICO from UniProt viral sequences

Domain architecture


Domain assignment details

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Strong hits

Sequence:  D2IE12_9PICO
Domain Number 1 Region: 1715-2175
Classification Level Classification E-value
Superfamily DNA/RNA polymerases 9.89e-113
Family RNA-dependent RNA-polymerase 0.0000177
Further Details:      
 
Domain Number 2 Region: 33-278
Classification Level Classification E-value
Superfamily Positive stranded ssRNA viruses 1.14e-50
Family Picornaviridae-like VP (VP1, VP2, VP3 and VP4) 0.0041
Further Details:      
 
Domain Number 3 Region: 283-539
Classification Level Classification E-value
Superfamily Positive stranded ssRNA viruses 2.9e-50
Family Picornaviridae-like VP (VP1, VP2, VP3 and VP4) 0.0043
Further Details:      
 
Domain Number 4 Region: 556-757
Classification Level Classification E-value
Superfamily Positive stranded ssRNA viruses 1.47e-28
Family Picornaviridae-like VP (VP1, VP2, VP3 and VP4) 0.038
Further Details:      
 
Domain Number 5 Region: 1514-1700
Classification Level Classification E-value
Superfamily Trypsin-like serine proteases 1.18e-27
Family Viral cysteine protease of trypsin fold 0.022
Further Details:      
 
Domain Number 6 Region: 1150-1305
Classification Level Classification E-value
Superfamily P-loop containing nucleoside triphosphate hydrolases 0.00000000621
Family RecA protein-like (ATPase-domain) 0.086
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score

Protein sequence

External link(s) D2IE12_9PICO
Sequence length 2179
Comment AC=D2IE12; DE=SubName: Full=Polyprotein; OS=Human parechovirus 1. OC=Viruses; ssRNA positive-strand viruses, no DNA stage; Picornavirales; OC=Picornaviridae; Parechovirus.
Sequence
METIKNIADMATGVVSSVDSTINVVNEKVENVGNEIGGNLLTKVADDASNVLGPNCYATT
AEPENKDVVQATTTVNTTNLTQHPSAPTMPFTPDFSNVDTFHSMAYDITTGEKNPSKLVR
LETHEWTPTWARGYQITHVELPKVFWDKNSKPAYGQSRYFAAVRCGFHFQVQVNVNQGTA
GSALVVYEPKPVVTYDSKLEFGAFTNLPHVLMNLAETTQADLCIPYVADTNYVKTDSSDL
GQLKVYVWTPLSIPSGSATQVDVTILGSLLQLDFQNPRVFGQDVGIYDNSPTRKQNLKKI
LTMSTKYKWTRQKIDIAEGPGSMNMANVLSTTAAQSVALVGERAFYDPRTAGSKSRFDDL
VKISQLFSVMSDSTTPSANHGIDAKGYFKWSSTTAPQSVVHRNIVYLKLFPNLNVFVNSY
SYFRGSMVLRLSVYASTFNRGRLRMGFFPNATEDSTSEIDNAIYTICDLGSDNSFEITIP
YSFSTWMRKTDGHPIGLFQIEVLNRLTYNSSSPNEVYCIVQGKMGQDARFFCPTGSVVTF
QNSWGSQMDLTDPLCLEESAEECKQTISPNELGLTSAQDDGPLGDNKPNYFLNFKSMNVD
IFTVSHTKVDNLFGRAWFFQEHTFTNEGQWRVSLEFPKQGHGSLSLLFAYFTGELNIHVL
FLAEKGFLRVAHTYDTSENRVNFLSSNGVITIPAGEQMTLSAPYYSNKPLRTVRDSNSLG
YLMCKPFLTGTTTGKIEVYLSLRCPNFFFPLPAPKVTTSRALRGDLANFSDQSPYGQQPQ
NQIMKLAYLDRGFYKHYGIIVDGYVYQLDSDDIFKTALTGKARFTKTKLTSDWIVEEECE
LDYFRVKYLESSVNSEHIFSVDSNCETIAKDIFGTHTLSQHQAIGLVGTILLTAGLMSTI
KTPVNATTIKEFFNHAVDGDEQGLSLLVQKCTTFFSSAATEILDNDLVKFIVKILVRILC
YMVLYCHKPNILTTACLSTLLIMDVTSSSVLSPSCKALMQCLMDGDVKKLAEVVAESMSN
TDDDEIKEQICDTVKYTKTILSNQGPFKGFNEVSTAFRHIDWWIHTLLKIKDMVLSVFKP
SLESKAIQWLERNKEHVCGILDYASDIIVESKDQSKVKTQDFYQRYSDCLAKFKPIMAIC
FRSCHNSISNTVYRLFQELARIPNRISTNNDLIRIEPIGIWIQGEPGQGKSFLTHTLSRQ
LQKSCKLNGVFTNPTASEFMDGYDNQDIHLIDDLGQTRKEKDIEMLCNCISSVPFIVPMA
HLEEKGKFYTSKLVIATTNKSDFSSTVLQDSGALKRRFPYIMHIRAAKAYSKAGKLNVSQ
AMATMSTGECWEVSKNGRDWETLKLKDLVDKITADYTERVKNYNAWKQQLENQTLDDLDD
AVSYIKHNFPDAVPYIDEYLNIEMSTLIEQMEAFIEPKPSVFKCFANKIGSKISKASREV
VDWFSDKIKSMLSFVERNKAWLTVVSAVTSAISILLLVTKIFKKEDSKDERAYNPTLPVA
KSKGTFPISQREFKNEAPYDGQLEHIISQMAYITGSTTGHLTHCAGYQHDEIILHGHSIK
YLEQEEELTLHYKNKVFPVESPSVTQVTLGGKPMDLAILKCKLPFRFKKNSKYYTNKIGT
ESMLIWMTEQGIITKEVQRVHHSGGIKTREGTESTKTISYTVKSCKGMCGGLLISKVEGN
FKILGMHIAGNGEMGVAIPFNFLKNDMSDQGIVTEVTPIQPMYINTKSQIHKSPVYGAVE
VKMGPAVLSKSDTRLEEPIDCLIKKSASKYRVNKFQVNNELWQGVKACVKSKFREIFGVN
GIVDMKTAILGTTHVNSMDLSTSAGYSFVKSGYKKKDLICLEPFSVSPMLEKLVQEKFHN
LLKGNQITTIFNTCLKDELRKLDKIAAGKTRCIEACEVDYCIVYRMIMMEIYDKIYQTPC
YYSGLAVGINPYKDWHFMINALNDYNYEMDYSQYDGSLSSMLLWEAVEVLAYCHDTPDLV
MQLHKPVIDSDHIVFNERWLIHGGMPSGSPCTTVLNSLCNLMMCIYTANLISPGIDCLPI
VYGDDVILSLDKEIEPEKLQSIMAESFGVEVTGSRKDEPPTLKPIMEVEFLKRKPGYFPE
STFIVGKLDTENMIQHLMWMKNFSTFKQQLQSYLMELCLHGKDTYLHYIKILDPYLKEWN
ITVDDYEVVIAKLMPMVFD
Download sequence
Identical sequences D2IE12
D2IE12_9PICO

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