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Domain assignment for D2IE16_9PICO from UniProt viral sequences

Domain architecture


Domain assignment details

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Strong hits

Sequence:  D2IE16_9PICO
Domain Number 1 Region: 1715-2174
Classification Level Classification E-value
Superfamily DNA/RNA polymerases 3.21e-112
Family RNA-dependent RNA-polymerase 0.0000166
Further Details:      
 
Domain Number 2 Region: 282-539
Classification Level Classification E-value
Superfamily Positive stranded ssRNA viruses 7.29e-51
Family Picornaviridae-like VP (VP1, VP2, VP3 and VP4) 0.0044
Further Details:      
 
Domain Number 3 Region: 33-278
Classification Level Classification E-value
Superfamily Positive stranded ssRNA viruses 1.68e-50
Family Picornaviridae-like VP (VP1, VP2, VP3 and VP4) 0.0035
Further Details:      
 
Domain Number 4 Region: 556-756
Classification Level Classification E-value
Superfamily Positive stranded ssRNA viruses 4.84e-29
Family Picornaviridae-like VP (VP1, VP2, VP3 and VP4) 0.038
Further Details:      
 
Domain Number 5 Region: 1514-1700
Classification Level Classification E-value
Superfamily Trypsin-like serine proteases 1.03e-27
Family Viral cysteine protease of trypsin fold 0.016
Further Details:      
 
Domain Number 6 Region: 1149-1305
Classification Level Classification E-value
Superfamily P-loop containing nucleoside triphosphate hydrolases 0.00000000172
Family RecA protein-like (ATPase-domain) 0.079
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) D2IE16_9PICO
Sequence length 2179
Comment AC=D2IE16; DE=SubName: Full=Polyprotein; OS=Human parechovirus 1. OC=Viruses; ssRNA positive-strand viruses, no DNA stage; Picornavirales; OC=Picornaviridae; Parechovirus.
Sequence
METIKNIADMATGVVSSVDSTINAVNEKVENVGNEIGGNLLTKVADDASNVLGPNCYATT
AEPENKDVVQATTTVNTTNLTQHPSAPTMPFTPDFSNVDTFHSMAYDITTGEKNPSKLVR
LETHEWTPTWARGHQITHVELPKVFWDKNSKPAYGQSRYFAAVRCGFHFQVQVNVNQGTA
GSALVVYEPKPVVTYDTKLEFGAFTNLPHVLMNLAETTQADLCIPYVADTNYVKTDSSDL
GQLKVYVWTPLSIPSGSATQVDVTILGSLLQLDFQNPRVFGQDVGIYDNAPTRKQNLKKI
LTMSTKYKWTRQKIDIAEGPGSMNMANVLSTTAAQSIALVGERAFYDPRTAGSKSRFDDL
VKISQLFSVMSDSTTPSANHGIDAKGYFKWSSTTAPQSVVHRNIVYLKQFPNLNVFVNSY
SYFRGSIVLRLSVYASTFNRGRLRMGFFPNATEDSTSEIDNAIYTICDLGSDNSFEITIP
YSFSTWMRKTDGHPIGLFQIEVLNRLTYNSSSPNEVYCIVQGKMGQDARFFCPTGSVVTF
QNSWGSQMDLTDPLCLEESAEECKQTISPNELGLTSAQDDGPLGDNKPNYFLNFKSMNVD
IFTVSHTKVDNLFGRAWFYQEHTFTNEGQWRVNLEFPKQGHGSLSLLFAYFTGELNIHVL
FLAEKGFLRVAHTYDTSENRVNFLSSNGVITIPAGEQMTLSAPYYSNKPLRTVRDNNSLG
YLMCKPFLTGTTTGKIEVYLSLRCPNFFFPLPAPKVTTGRALRGDLANFSDQSLYDQQSQ
SQVMKLAYLDRGFYKHYGIIVGDSVYQLDSDDIFKTALTGKAKFTKTKLTPDWVIEEECE
LDYFRVKYLESSVNSEHIFSVDHNCETIAKDIFGTHTLSQHQAVGLIGTILLTAGLMSTI
KTPVNATTIKEFFNHAVEGDEQGLSLLVQKCTTFFSSAATEILDNDLVKFIVKILVRILC
YMVLYCHKPNILTTACLSTLLIMDVTSSSVLSPSCKALMQCLMDGDVKKLAEVVAESMSN
TDDEEIKEQICDTVKYTKSILSNQGPFKGFNEVSTAFRHIDWWIHTLLKIKDMVLSVFKP
SMESKAIQWLERNKEHVCAVLDYASDIIVESKDQTKMKSQEFYQKYTDCLSKFKPIMAIC
FRSCHNSISNTVYRLFQELARIPSRISTQNDLIRVEPIGVWIQGEPGQGKSFLTHTLSRQ
LQKSCKLNGVYTNPTASEFMDGYDNQDIHLIDDLGQTRKEKDIEMLCNCISSVPFIVPMA
HLEEKGKFYTSKLVIATTNKSDFSSTVLQDSGALKRRFPYIMHIRAAKAYSKAGKLNVSQ
AMSTMATGECWEVSKNGRDWETLRLKDLVHKITEDYQERQKNYDCWKQQLENQTLDDLDD
AVSYIKHNFPDAVPYIDEYLNIEMSTLIEQMEAFIEPRPSVFKCFATKVANQTKKATKEV
VEWFSSKIKSMLSFVEKNKAWLTVVSAVTSAISILLLVTKIFKKEDSKDERAYNPTLPVT
KPKGTFPVTQREFKNEAPYDGQLEHIISQMAYITGSTTGHLTHCAGYQHDEIILHGHSIK
YLEQEEELTLHYKNKVFPVECPSVTQVTLGGKPMDLAILKCKLPFRFKKNSKYYTNKIGT
ENMLIWMTEQGIITKEVQRVHHSGGIKTREGTESTKTISYTVKSCKGMCGGLLISKVEGN
FKILGMHIAGNGEMGVAIPFNFLKNDMSDQGIVTEVTPIQPMYINTKTQIHKSPVYGAVE
VKMGPAVLSKSDPRLEEPVECLIKKSAAKYRVNKFHVNNELWQGVKACVKSKFREIFGIN
GIVDMKTAILGTSHVNSMDLSTSAGYSFVKAGYKKKDLICLEPFSISPMLEKLVQEKFHN
LLKGNQITTIFNTCLKDELRKLDKISAGKTRCIEACEVDYCIVYRMIMMEIYDKIYQTPC
YYSGLAVGINPYKDWHFMINALNDYNYEMDYSQYDGSLSSMLLWEAVEVLAYCHDSPDLV
IQLHRPVIDSDHVVFNERWLIHGGMPSGSPCTTVLNSLCNLMMCIYTTNLISPGIDCLPI
VYGDDVILSLDKEIDPEKLQSIMADSFGAEVTGSRKDEPPSLKPRLEVEFLKRKPGYFPE
STFIVGKLDTENMIQHLMWMKNFSTFKQQLQSYLMELCLHGKDTYLHYIKILDPYLKEWN
IIVDDYDVVITKLMPMVFD
Download sequence
Identical sequences D2IE16
D2IE16_9PICO

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